KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZNF236
Full Name:
Zinc finger protein 236
Alias:
Regulated by glucose; ZN236; ZNF236A; ZNF236B
Type:
Mass (Da):
203660
Number AA:
1845
UniProt ID:
Q9UL36
International Prot ID:
IPI00007777
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y29
L
N
A
E
N
T
N
Y
A
Y
Q
V
P
N
F
Site 2
Y31
A
E
N
T
N
Y
A
Y
Q
V
P
N
F
H
K
Site 3
S45
K
C
E
I
C
L
L
S
F
P
K
E
S
Q
F
Site 4
S50
L
L
S
F
P
K
E
S
Q
F
Q
R
H
M
R
Site 5
T87
N
L
T
L
H
K
C
T
H
S
G
E
D
P
T
Site 6
S89
T
L
H
K
C
T
H
S
G
E
D
P
T
C
P
Site 7
T94
T
H
S
G
E
D
P
T
C
P
V
C
N
K
K
Site 8
S103
P
V
C
N
K
K
F
S
R
V
A
S
L
K
A
Site 9
S124
K
E
E
N
L
I
C
S
E
C
G
D
E
F
T
Site 10
T131
S
E
C
G
D
E
F
T
L
Q
S
Q
L
A
V
Site 11
S134
G
D
E
F
T
L
Q
S
Q
L
A
V
H
M
E
Site 12
S165
C
K
K
E
F
E
T
S
S
E
L
K
E
H
M
Site 13
S166
K
K
E
F
E
T
S
S
E
L
K
E
H
M
K
Site 14
T174
E
L
K
E
H
M
K
T
H
Y
K
I
R
V
S
Site 15
Y176
K
E
H
M
K
T
H
Y
K
I
R
V
S
S
T
Site 16
S181
T
H
Y
K
I
R
V
S
S
T
R
S
Y
N
R
Site 17
S182
H
Y
K
I
R
V
S
S
T
R
S
Y
N
R
N
Site 18
S185
I
R
V
S
S
T
R
S
Y
N
R
N
I
D
R
Site 19
Y186
R
V
S
S
T
R
S
Y
N
R
N
I
D
R
S
Site 20
Y197
I
D
R
S
G
F
T
Y
S
C
P
H
C
G
K
Site 21
T205
S
C
P
H
C
G
K
T
F
Q
K
P
S
Q
L
Site 22
S210
G
K
T
F
Q
K
P
S
Q
L
T
R
H
I
R
Site 23
T220
T
R
H
I
R
I
H
T
G
E
R
P
F
K
C
Site 24
S228
G
E
R
P
F
K
C
S
E
C
G
K
A
F
N
Site 25
S263
A
F
C
P
A
A
F
S
Q
K
G
N
L
Q
S
Site 26
S270
S
Q
K
G
N
L
Q
S
H
V
Q
R
V
H
S
Site 27
S277
S
H
V
Q
R
V
H
S
E
V
K
N
G
P
T
Site 28
Y285
E
V
K
N
G
P
T
Y
N
C
T
E
C
S
C
Site 29
S296
E
C
S
C
V
F
K
S
L
G
S
L
N
T
H
Site 30
T302
K
S
L
G
S
L
N
T
H
I
S
K
M
H
M
Site 31
S315
H
M
G
G
P
Q
N
S
T
S
S
T
E
T
A
Site 32
S317
G
G
P
Q
N
S
T
S
S
T
E
T
A
H
V
Site 33
T319
P
Q
N
S
T
S
S
T
E
T
A
H
V
L
T
Site 34
T321
N
S
T
S
S
T
E
T
A
H
V
L
T
A
T
Site 35
T343
Q
Q
T
E
A
Q
A
T
S
A
S
S
Q
P
S
Site 36
S344
Q
T
E
A
Q
A
T
S
A
S
S
Q
P
S
S
Site 37
S346
E
A
Q
A
T
S
A
S
S
Q
P
S
S
Q
A
Site 38
S347
A
Q
A
T
S
A
S
S
Q
P
S
S
Q
A
V
Site 39
S350
T
S
A
S
S
Q
P
S
S
Q
A
V
S
D
V
Site 40
S351
S
A
S
S
Q
P
S
S
Q
A
V
S
D
V
I
Site 41
S355
Q
P
S
S
Q
A
V
S
D
V
I
Q
Q
L
L
Site 42
S365
I
Q
Q
L
L
E
L
S
E
P
A
P
V
E
S
Site 43
S372
S
E
P
A
P
V
E
S
G
Q
S
P
Q
P
G
Site 44
S375
A
P
V
E
S
G
Q
S
P
Q
P
G
Q
Q
L
Site 45
S383
P
Q
P
G
Q
Q
L
S
I
T
V
G
I
N
Q
Site 46
T385
P
G
Q
Q
L
S
I
T
V
G
I
N
Q
D
I
Site 47
S400
L
Q
Q
A
L
E
N
S
G
L
S
S
I
P
A
Site 48
S404
L
E
N
S
G
L
S
S
I
P
A
A
A
H
P
Site 49
S414
A
A
A
H
P
N
D
S
C
H
A
K
T
S
A
Site 50
S431
A
Q
N
P
D
V
S
S
V
S
N
E
Q
T
D
Site 51
T437
S
S
V
S
N
E
Q
T
D
P
T
D
A
E
Q
Site 52
T440
S
N
E
Q
T
D
P
T
D
A
E
Q
E
K
E
Site 53
S450
E
Q
E
K
E
Q
E
S
P
E
K
L
D
K
K
Site 54
S466
K
K
M
I
K
K
K
S
P
F
L
P
G
S
I
Site 55
S472
K
S
P
F
L
P
G
S
I
R
E
E
N
G
V
Site 56
S495
A
K
E
F
R
K
P
S
D
L
V
R
H
I
R
Site 57
T505
V
R
H
I
R
I
H
T
H
E
K
P
F
K
C
Site 58
Y542
I
K
A
F
K
C
Q
Y
C
M
K
S
F
S
T
Site 59
S546
K
C
Q
Y
C
M
K
S
F
S
T
S
G
S
L
Site 60
S548
Q
Y
C
M
K
S
F
S
T
S
G
S
L
K
V
Site 61
S552
K
S
F
S
T
S
G
S
L
K
V
H
I
R
L
Site 62
T583
R
T
S
G
H
R
K
T
H
I
A
S
H
F
K
Site 63
T611
A
K
V
R
V
G
K
T
N
V
P
V
P
D
I
Site 64
S643
P
K
N
Q
F
F
Q
S
Y
F
N
N
N
F
V
Site 65
Y644
K
N
Q
F
F
Q
S
Y
F
N
N
N
F
V
N
Site 66
Y657
V
N
E
A
D
R
P
Y
K
C
F
Y
C
H
R
Site 67
Y661
D
R
P
Y
K
C
F
Y
C
H
R
A
Y
K
K
Site 68
T680
K
Q
H
I
R
S
H
T
G
E
K
P
F
K
C
Site 69
S688
G
E
K
P
F
K
C
S
Q
C
G
R
G
F
V
Site 70
T708
K
A
H
I
R
T
H
T
G
L
K
S
F
K
C
Site 71
S727
G
A
F
T
T
G
G
S
L
R
R
H
M
G
I
Site 72
Y741
I
H
N
D
L
R
P
Y
M
C
P
Y
C
Q
K
Site 73
Y745
L
R
P
Y
M
C
P
Y
C
Q
K
T
F
K
T
Site 74
T762
N
C
K
K
H
M
K
T
H
R
Y
E
L
A
Q
Site 75
S779
Q
Q
H
Q
Q
A
A
S
I
D
D
S
T
V
D
Site 76
S783
Q
A
A
S
I
D
D
S
T
V
D
Q
Q
S
M
Site 77
T784
A
A
S
I
D
D
S
T
V
D
Q
Q
S
M
Q
Site 78
S789
D
S
T
V
D
Q
Q
S
M
Q
A
S
T
Q
M
Site 79
S793
D
Q
Q
S
M
Q
A
S
T
Q
M
Q
V
E
I
Site 80
T808
E
S
D
E
L
P
Q
T
A
E
V
V
A
A
N
Site 81
S869
V
D
Q
F
E
E
Q
S
P
A
Q
Q
S
F
E
Site 82
S874
E
Q
S
P
A
Q
Q
S
F
E
P
A
G
L
P
Site 83
T885
A
G
L
P
Q
G
F
T
V
T
D
T
Y
H
Q
Site 84
Y890
G
F
T
V
T
D
T
Y
H
Q
Q
P
Q
F
P
Site 85
S905
P
V
Q
Q
L
Q
D
S
S
T
L
E
S
Q
A
Site 86
S906
V
Q
Q
L
Q
D
S
S
T
L
E
S
Q
A
L
Site 87
T907
Q
Q
L
Q
D
S
S
T
L
E
S
Q
A
L
S
Site 88
S910
Q
D
S
S
T
L
E
S
Q
A
L
S
T
S
F
Site 89
S914
T
L
E
S
Q
A
L
S
T
S
F
H
Q
Q
S
Site 90
S916
E
S
Q
A
L
S
T
S
F
H
Q
Q
S
L
L
Site 91
S921
S
T
S
F
H
Q
Q
S
L
L
Q
A
P
S
S
Site 92
S927
Q
S
L
L
Q
A
P
S
S
D
G
M
N
V
T
Site 93
S928
S
L
L
Q
A
P
S
S
D
G
M
N
V
T
T
Site 94
T934
S
S
D
G
M
N
V
T
T
R
L
I
Q
E
S
Site 95
S941
T
T
R
L
I
Q
E
S
S
Q
E
E
L
D
L
Site 96
S942
T
R
L
I
Q
E
S
S
Q
E
E
L
D
L
Q
Site 97
S953
L
D
L
Q
A
Q
G
S
Q
F
L
E
D
N
E
Site 98
S963
L
E
D
N
E
D
Q
S
R
R
S
Y
R
C
D
Site 99
Y967
E
D
Q
S
R
R
S
Y
R
C
D
Y
C
N
K
Site 100
Y971
R
R
S
Y
R
C
D
Y
C
N
K
G
F
K
K
Site 101
T990
K
Q
H
V
R
S
H
T
G
E
K
P
Y
K
C
Site 102
Y995
S
H
T
G
E
K
P
Y
K
C
K
L
C
G
R
Site 103
S1007
C
G
R
G
F
V
S
S
G
V
L
K
S
H
E
Site 104
S1012
V
S
S
G
V
L
K
S
H
E
K
T
H
T
G
Site 105
T1016
V
L
K
S
H
E
K
T
H
T
G
V
K
A
F
Site 106
T1018
K
S
H
E
K
T
H
T
G
V
K
A
F
S
C
Site 107
T1033
S
V
C
N
A
S
F
T
T
N
G
S
L
T
R
Site 108
S1037
A
S
F
T
T
N
G
S
L
T
R
H
M
A
T
Site 109
Y1051
T
H
M
S
M
K
P
Y
K
C
P
F
C
E
E
Site 110
T1075
K
H
M
K
R
H
Q
T
V
P
S
A
V
S
A
Site 111
S1078
K
R
H
Q
T
V
P
S
A
V
S
A
T
G
E
Site 112
S1100
M
E
E
E
E
E
H
S
D
R
N
A
S
R
K
Site 113
S1105
E
H
S
D
R
N
A
S
R
K
S
R
P
E
V
Site 114
S1108
D
R
N
A
S
R
K
S
R
P
E
V
I
T
F
Site 115
T1114
K
S
R
P
E
V
I
T
F
T
E
E
E
T
A
Site 116
S1131
A
K
I
R
P
Q
E
S
A
T
V
S
E
K
V
Site 117
T1133
I
R
P
Q
E
S
A
T
V
S
E
K
V
L
V
Site 118
S1135
P
Q
E
S
A
T
V
S
E
K
V
L
V
Q
S
Site 119
S1150
A
A
E
K
D
R
I
S
E
L
R
D
K
Q
A
Site 120
Y1171
K
H
A
N
C
C
T
Y
C
P
K
S
F
K
K
Site 121
S1180
P
K
S
F
K
K
P
S
D
L
V
R
H
V
R
Site 122
T1190
V
R
H
V
R
I
H
T
G
E
K
P
Y
K
C
Site 123
Y1195
I
H
T
G
E
K
P
Y
K
C
D
E
C
G
K
Site 124
S1203
K
C
D
E
C
G
K
S
F
T
V
K
S
T
L
Site 125
S1208
G
K
S
F
T
V
K
S
T
L
D
C
H
V
K
Site 126
S1233
H
V
C
S
N
A
F
S
T
K
G
S
L
K
V
Site 127
S1237
N
A
F
S
T
K
G
S
L
K
V
H
M
R
L
Site 128
T1246
K
V
H
M
R
L
H
T
G
A
K
P
F
K
C
Site 129
T1262
H
C
E
L
R
F
R
T
S
G
R
R
K
T
H
Site 130
S1263
C
E
L
R
F
R
T
S
G
R
R
K
T
H
M
Site 131
T1268
R
T
S
G
R
R
K
T
H
M
Q
F
H
Y
K
Site 132
T1286
K
K
A
R
K
P
M
T
R
S
S
S
E
G
L
Site 133
S1288
A
R
K
P
M
T
R
S
S
S
E
G
L
Q
P
Site 134
S1289
R
K
P
M
T
R
S
S
S
E
G
L
Q
P
V
Site 135
S1290
K
P
M
T
R
S
S
S
E
G
L
Q
P
V
N
Site 136
S1301
Q
P
V
N
L
L
N
S
S
S
T
D
P
N
V
Site 137
S1302
P
V
N
L
L
N
S
S
S
T
D
P
N
V
F
Site 138
T1410
N
L
L
A
Q
Q
L
T
G
E
P
G
L
A
P
Site 139
S1420
P
G
L
A
P
Q
N
S
S
L
Q
T
S
D
S
Site 140
S1421
G
L
A
P
Q
N
S
S
L
Q
T
S
D
S
T
Site 141
T1424
P
Q
N
S
S
L
Q
T
S
D
S
T
V
P
A
Site 142
S1425
Q
N
S
S
L
Q
T
S
D
S
T
V
P
A
S
Site 143
S1427
S
S
L
Q
T
S
D
S
T
V
P
A
S
V
V
Site 144
T1453
T
V
T
S
A
N
L
T
I
G
P
L
S
E
Q
Site 145
S1458
N
L
T
I
G
P
L
S
E
Q
D
S
V
L
T
Site 146
S1462
G
P
L
S
E
Q
D
S
V
L
T
T
N
S
S
Site 147
T1465
S
E
Q
D
S
V
L
T
T
N
S
S
G
T
Q
Site 148
T1466
E
Q
D
S
V
L
T
T
N
S
S
G
T
Q
D
Site 149
S1469
S
V
L
T
T
N
S
S
G
T
Q
D
L
T
Q
Site 150
T1475
S
S
G
T
Q
D
L
T
Q
V
M
T
S
Q
G
Site 151
S1480
D
L
T
Q
V
M
T
S
Q
G
L
V
S
P
S
Site 152
S1485
M
T
S
Q
G
L
V
S
P
S
G
G
P
H
E
Site 153
S1487
S
Q
G
L
V
S
P
S
G
G
P
H
E
I
T
Site 154
T1494
S
G
G
P
H
E
I
T
L
T
I
N
N
S
S
Site 155
T1496
G
P
H
E
I
T
L
T
I
N
N
S
S
L
S
Site 156
T1513
L
A
Q
A
A
G
P
T
A
T
S
S
S
G
S
Site 157
S1516
A
A
G
P
T
A
T
S
S
S
G
S
P
Q
E
Site 158
S1517
A
G
P
T
A
T
S
S
S
G
S
P
Q
E
I
Site 159
S1518
G
P
T
A
T
S
S
S
G
S
P
Q
E
I
T
Site 160
S1520
T
A
T
S
S
S
G
S
P
Q
E
I
T
L
T
Site 161
T1525
S
G
S
P
Q
E
I
T
L
T
I
S
E
L
N
Site 162
T1527
S
P
Q
E
I
T
L
T
I
S
E
L
N
T
T
Site 163
S1529
Q
E
I
T
L
T
I
S
E
L
N
T
T
S
G
Site 164
T1533
L
T
I
S
E
L
N
T
T
S
G
S
L
P
S
Site 165
T1534
T
I
S
E
L
N
T
T
S
G
S
L
P
S
T
Site 166
S1535
I
S
E
L
N
T
T
S
G
S
L
P
S
T
T
Site 167
S1537
E
L
N
T
T
S
G
S
L
P
S
T
T
P
T
Site 168
S1540
T
T
S
G
S
L
P
S
T
T
P
T
S
P
S
Site 169
T1541
T
S
G
S
L
P
S
T
T
P
T
S
P
S
A
Site 170
T1542
S
G
S
L
P
S
T
T
P
T
S
P
S
A
I
Site 171
T1544
S
L
P
S
T
T
P
T
S
P
S
A
I
S
T
Site 172
S1545
L
P
S
T
T
P
T
S
P
S
A
I
S
T
Q
Site 173
S1547
S
T
T
P
T
S
P
S
A
I
S
T
Q
N
L
Site 174
S1550
P
T
S
P
S
A
I
S
T
Q
N
L
V
M
S
Site 175
T1551
T
S
P
S
A
I
S
T
Q
N
L
V
M
S
S
Site 176
S1557
S
T
Q
N
L
V
M
S
S
S
G
V
G
G
D
Site 177
S1559
Q
N
L
V
M
S
S
S
G
V
G
G
D
A
S
Site 178
T1586
S
G
G
L
D
T
V
T
L
N
I
T
S
Q
G
Site 179
T1601
Q
Q
F
P
A
L
L
T
D
P
S
L
S
G
Q
Site 180
S1604
P
A
L
L
T
D
P
S
L
S
G
Q
G
G
A
Site 181
S1606
L
L
T
D
P
S
L
S
G
Q
G
G
A
G
S
Site 182
S1620
S
P
Q
V
I
L
V
S
H
T
P
Q
S
A
S
Site 183
S1625
L
V
S
H
T
P
Q
S
A
S
A
A
C
E
E
Site 184
T1699
R
K
A
F
K
R
A
T
H
L
K
E
H
M
Q
Site 185
T1707
H
L
K
E
H
M
Q
T
H
Q
A
G
P
S
L
Site 186
S1713
Q
T
H
Q
A
G
P
S
L
S
S
Q
K
P
R
Site 187
S1716
Q
A
G
P
S
L
S
S
Q
K
P
R
V
F
K
Site 188
T1726
P
R
V
F
K
C
D
T
C
E
K
A
F
A
K
Site 189
S1735
E
K
A
F
A
K
P
S
Q
L
E
R
H
S
R
Site 190
S1741
P
S
Q
L
E
R
H
S
R
I
H
T
G
E
R
Site 191
T1745
E
R
H
S
R
I
H
T
G
E
R
P
F
H
C
Site 192
S1763
E
K
A
F
N
Q
K
S
A
L
Q
V
H
M
K
Site 193
Y1778
K
H
T
G
E
R
P
Y
K
C
A
Y
C
V
M
Site 194
Y1782
E
R
P
Y
K
C
A
Y
C
V
M
G
F
T
Q
Site 195
S1802
L
H
M
K
R
A
H
S
Y
A
G
A
L
Q
E
Site 196
S1822
E
Q
D
G
E
E
L
S
R
T
L
H
L
E
E
Site 197
T1824
D
G
E
E
L
S
R
T
L
H
L
E
E
V
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation