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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TCFL5
Full Name:
Alias:
Type:
Mass (Da):
52697
Number AA:
500
UniProt ID:
Q9UL49
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T55
E
M
T
E
V
E
Y
T
Q
L
Q
H
I
L
C
Site 2
S135
E
L
R
M
M
L
L
S
E
A
G
A
A
E
K
Site 3
S144
A
G
A
A
E
K
T
S
G
G
G
D
G
A
R
Site 4
S193
R
L
E
D
R
F
N
S
I
P
A
E
P
P
P
Site 5
T219
G
A
L
N
N
L
V
T
L
I
R
H
P
S
E
Site 6
S266
L
F
T
T
N
A
C
S
T
S
G
N
S
N
L
Site 7
S268
T
T
N
A
C
S
T
S
G
N
S
N
L
S
Q
Site 8
S274
T
S
G
N
S
N
L
S
Q
T
Q
S
S
S
N
Site 9
T276
G
N
S
N
L
S
Q
T
Q
S
S
S
N
S
C
Site 10
S278
S
N
L
S
Q
T
Q
S
S
S
N
S
C
S
V
Site 11
S279
N
L
S
Q
T
Q
S
S
S
N
S
C
S
V
L
Site 12
S280
L
S
Q
T
Q
S
S
S
N
S
C
S
V
L
E
Site 13
S282
Q
T
Q
S
S
S
N
S
C
S
V
L
E
A
A
Site 14
S284
Q
S
S
S
N
S
C
S
V
L
E
A
A
K
H
Site 15
S301
I
G
L
P
R
A
F
S
F
C
Y
Q
Q
E
I
Site 16
Y304
P
R
A
F
S
F
C
Y
Q
Q
E
I
E
S
T
Site 17
T311
Y
Q
Q
E
I
E
S
T
K
Q
T
L
G
S
R
Site 18
T314
E
I
E
S
T
K
Q
T
L
G
S
R
N
K
V
Site 19
S345
Q
A
L
K
R
N
R
S
R
M
R
Q
L
D
T
Site 20
T352
S
R
M
R
Q
L
D
T
N
V
E
R
R
A
L
Site 21
S378
A
T
Q
G
A
W
Q
S
S
E
S
S
Q
A
N
Site 22
S379
T
Q
G
A
W
Q
S
S
E
S
S
Q
A
N
L
Site 23
S382
A
W
Q
S
S
E
S
S
Q
A
N
L
G
E
Q
Site 24
S392
N
L
G
E
Q
A
Q
S
G
P
Q
G
G
R
S
Site 25
S399
S
G
P
Q
G
G
R
S
Q
R
R
E
R
H
N
Site 26
S457
I
Q
E
R
H
G
D
S
L
K
K
E
F
E
S
Site 27
S464
S
L
K
K
E
F
E
S
V
F
C
G
K
T
G
Site 28
T470
E
S
V
F
C
G
K
T
G
R
R
L
K
L
T
Site 29
T477
T
G
R
R
L
K
L
T
R
P
D
S
L
V
T
Site 30
S481
L
K
L
T
R
P
D
S
L
V
T
C
P
A
Q
Site 31
S490
V
T
C
P
A
Q
G
S
L
Q
S
S
P
S
M
Site 32
S494
A
Q
G
S
L
Q
S
S
P
S
M
E
I
K
_
Site 33
S496
G
S
L
Q
S
S
P
S
M
E
I
K
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation