KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FAM184B
Full Name:
Alias:
Type:
Mass (Da):
121044
Number AA:
1060
UniProt ID:
Q9ULE4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
S
A
L
N
S
K
I
N
P
P
G
T
Site 2
T14
S
K
I
N
P
P
G
T
C
Q
G
S
K
A
D
Site 3
S18
P
P
G
T
C
Q
G
S
K
A
D
G
G
A
G
Site 4
S62
R
Q
D
E
A
E
A
S
M
E
A
L
R
E
A
Site 5
T115
L
E
L
Q
K
R
L
T
E
E
A
L
A
E
S
Site 6
S124
E
A
L
A
E
S
A
S
C
R
L
E
T
K
E
Site 7
T129
S
A
S
C
R
L
E
T
K
E
R
E
L
R
V
Site 8
T146
E
H
A
E
R
V
L
T
L
S
R
E
M
L
E
Site 9
S148
A
E
R
V
L
T
L
S
R
E
M
L
E
L
K
Site 10
Y158
M
L
E
L
K
A
D
Y
E
R
R
L
Q
H
L
Site 11
T166
E
R
R
L
Q
H
L
T
S
H
E
A
T
P
Q
Site 12
S167
R
R
L
Q
H
L
T
S
H
E
A
T
P
Q
G
Site 13
T171
H
L
T
S
H
E
A
T
P
Q
G
R
L
P
Q
Site 14
S180
Q
G
R
L
P
Q
E
S
P
E
T
K
S
E
P
Site 15
T183
L
P
Q
E
S
P
E
T
K
S
E
P
G
Q
G
Site 16
S185
Q
E
S
P
E
T
K
S
E
P
G
Q
G
P
E
Site 17
Y214
N
Q
Q
L
S
K
D
Y
A
R
K
A
E
E
L
Site 18
T224
K
A
E
E
L
Q
A
T
Y
E
R
E
N
E
A
Site 19
S239
I
R
Q
A
M
Q
Q
S
V
S
Q
A
L
W
Q
Site 20
S284
E
H
R
G
R
K
I
S
D
L
K
K
Y
A
Q
Site 21
Y289
K
I
S
D
L
K
K
Y
A
Q
K
L
K
E
R
Site 22
S312
K
E
A
R
Q
E
N
S
E
L
K
G
T
A
K
Site 23
T317
E
N
S
E
L
K
G
T
A
K
K
L
G
E
K
Site 24
T340
M
L
Q
E
C
R
G
T
Q
Q
T
D
A
M
K
Site 25
T343
E
C
R
G
T
Q
Q
T
D
A
M
K
T
E
L
Site 26
T348
Q
Q
T
D
A
M
K
T
E
L
V
S
E
N
K
Site 27
T387
C
P
C
M
K
G
G
T
D
M
Q
T
K
K
E
Site 28
T391
K
G
G
T
D
M
Q
T
K
K
E
A
S
A
E
Site 29
T440
E
D
L
V
K
K
H
T
V
E
I
K
S
V
R
Site 30
S445
K
H
T
V
E
I
K
S
V
R
S
S
V
E
A
Site 31
S449
E
I
K
S
V
R
S
S
V
E
A
E
R
K
K
Site 32
S472
L
E
E
V
R
K
K
S
E
K
E
I
K
Q
L
Site 33
T512
Q
Q
N
K
T
R
P
T
G
A
E
E
S
P
Q
Site 34
S517
R
P
T
G
A
E
E
S
P
Q
E
L
G
R
Q
Site 35
T531
Q
H
C
S
I
L
E
T
Q
D
P
C
L
K
L
Site 36
T541
P
C
L
K
L
D
E
T
S
P
R
G
E
E
Y
Site 37
S542
C
L
K
L
D
E
T
S
P
R
G
E
E
Y
Q
Site 38
S560
A
A
E
E
G
T
S
S
D
E
E
E
R
T
K
Site 39
T566
S
S
D
E
E
E
R
T
K
V
L
L
K
E
G
Site 40
S574
K
V
L
L
K
E
G
S
D
P
Q
P
P
L
G
Site 41
S589
S
L
L
K
E
K
T
S
K
I
Q
R
L
E
E
Site 42
S600
R
L
E
E
D
W
Q
S
Q
K
A
K
L
Q
A
Site 43
S610
A
K
L
Q
A
Q
V
S
Q
M
Q
Q
A
L
E
Site 44
S621
Q
A
L
E
Q
C
T
S
N
Y
R
E
D
L
Q
Site 45
S634
L
Q
A
L
K
Q
L
S
D
L
E
R
E
K
L
Site 46
T648
L
Q
R
E
L
Q
E
T
T
Q
Q
N
H
A
M
Site 47
S662
M
K
A
Q
L
E
A
S
H
Q
R
A
L
R
M
Site 48
T681
R
H
Q
E
L
K
A
T
E
E
R
L
K
K
E
Site 49
S689
E
E
R
L
K
K
E
S
S
H
S
L
Q
I
Q
Site 50
S690
E
R
L
K
K
E
S
S
H
S
L
Q
I
Q
H
Site 51
S692
L
K
K
E
S
S
H
S
L
Q
I
Q
H
Q
T
Site 52
T699
S
L
Q
I
Q
H
Q
T
H
R
L
E
L
Q
A
Site 53
S732
Q
Q
A
L
L
L
E
S
L
R
Q
E
L
S
E
Site 54
S738
E
S
L
R
Q
E
L
S
E
Q
Q
A
A
C
S
Site 55
S768
L
G
R
Q
Q
A
S
S
Q
C
P
G
D
S
K
Site 56
T781
S
K
D
H
I
I
A
T
E
E
R
G
G
P
G
Site 57
S792
G
G
P
G
Q
A
G
S
P
P
G
A
A
G
Q
Site 58
S801
P
G
A
A
G
Q
G
S
G
E
G
C
G
L
W
Site 59
T845
Q
R
R
F
L
E
E
T
Q
Q
A
Q
R
A
R
Site 60
T856
Q
R
A
R
E
V
E
T
L
R
Q
E
H
R
K
Site 61
S893
L
E
A
E
L
K
D
S
G
E
K
P
G
K
G
Site 62
S902
E
K
P
G
K
G
A
S
R
P
E
D
L
Q
L
Site 63
T915
Q
L
I
G
R
L
Q
T
R
L
K
E
R
E
D
Site 64
T928
E
D
I
I
K
Q
L
T
E
E
R
R
F
H
Y
Site 65
Y935
T
E
E
R
R
F
H
Y
A
A
F
P
S
A
M
Site 66
S943
A
A
F
P
S
A
M
S
H
R
N
R
S
F
S
Site 67
S948
A
M
S
H
R
N
R
S
F
S
F
N
P
H
P
Site 68
S950
S
H
R
N
R
S
F
S
F
N
P
H
P
G
Y
Site 69
Y957
S
F
N
P
H
P
G
Y
L
T
P
S
M
K
K
Site 70
T959
N
P
H
P
G
Y
L
T
P
S
M
K
K
K
K
Site 71
S961
H
P
G
Y
L
T
P
S
M
K
K
K
K
V
E
Site 72
S972
K
K
V
E
D
V
P
S
R
V
V
S
V
P
N
Site 73
Y983
S
V
P
N
L
A
S
Y
A
K
N
F
L
S
G
Site 74
S989
S
Y
A
K
N
F
L
S
G
D
L
S
S
R
I
Site 75
S993
N
F
L
S
G
D
L
S
S
R
I
N
A
P
P
Site 76
T1002
R
I
N
A
P
P
I
T
T
S
P
S
L
D
P
Site 77
T1003
I
N
A
P
P
I
T
T
S
P
S
L
D
P
S
Site 78
S1004
N
A
P
P
I
T
T
S
P
S
L
D
P
S
P
Site 79
S1006
P
P
I
T
T
S
P
S
L
D
P
S
P
S
C
Site 80
S1010
T
S
P
S
L
D
P
S
P
S
C
G
R
T
Y
Site 81
S1012
P
S
L
D
P
S
P
S
C
G
R
T
Y
K
P
Site 82
T1016
P
S
P
S
C
G
R
T
Y
K
P
N
Q
S
T
Site 83
Y1017
S
P
S
C
G
R
T
Y
K
P
N
Q
S
T
D
Site 84
T1027
N
Q
S
T
D
A
K
T
A
T
R
T
P
D
G
Site 85
T1029
S
T
D
A
K
T
A
T
R
T
P
D
G
E
T
Site 86
T1031
D
A
K
T
A
T
R
T
P
D
G
E
T
A
Q
Site 87
S1048
E
A
Q
Q
K
Q
G
S
P
H
Q
E
W
F
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation