KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
KIAA1257
Full Name:
Alias:
Type:
Mass (Da):
46740
Number AA:
409
UniProt ID:
Q9ULG3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
E
W
E
E
D
P
A
S
I
E
P
I
S
S
I
Site 2
S19
P
A
S
I
E
P
I
S
S
I
T
S
F
Y
Q
Site 3
S20
A
S
I
E
P
I
S
S
I
T
S
F
Y
Q
S
Site 4
S23
E
P
I
S
S
I
T
S
F
Y
Q
S
T
S
E
Site 5
Y25
I
S
S
I
T
S
F
Y
Q
S
T
S
E
C
D
Site 6
S27
S
I
T
S
F
Y
Q
S
T
S
E
C
D
V
E
Site 7
S29
T
S
F
Y
Q
S
T
S
E
C
D
V
E
E
H
Site 8
S46
A
K
A
R
A
Q
E
S
D
S
D
R
P
C
S
Site 9
S48
A
R
A
Q
E
S
D
S
D
R
P
C
S
S
I
Site 10
S53
S
D
S
D
R
P
C
S
S
I
E
S
S
S
E
Site 11
S54
D
S
D
R
P
C
S
S
I
E
S
S
S
E
P
Site 12
S57
R
P
C
S
S
I
E
S
S
S
E
P
A
S
T
Site 13
S58
P
C
S
S
I
E
S
S
S
E
P
A
S
T
F
Site 14
S59
C
S
S
I
E
S
S
S
E
P
A
S
T
F
S
Site 15
S63
E
S
S
S
E
P
A
S
T
F
S
S
D
V
P
Site 16
T64
S
S
S
E
P
A
S
T
F
S
S
D
V
P
H
Site 17
S67
E
P
A
S
T
F
S
S
D
V
P
H
V
V
P
Site 18
Y93
N
M
G
Q
K
G
K
Y
A
S
L
I
E
K
Y
Site 19
S95
G
Q
K
G
K
Y
A
S
L
I
E
K
Y
K
K
Site 20
Y100
Y
A
S
L
I
E
K
Y
K
K
H
P
K
T
D
Site 21
T106
K
Y
K
K
H
P
K
T
D
S
S
V
T
K
M
Site 22
S108
K
K
H
P
K
T
D
S
S
V
T
K
M
R
R
Site 23
S109
K
H
P
K
T
D
S
S
V
T
K
M
R
R
F
Site 24
Y121
R
R
F
Y
H
I
E
Y
F
L
L
P
D
D
E
Site 25
T152
F
L
E
S
G
V
K
T
V
K
P
W
H
E
G
Site 26
T173
W
E
Q
T
F
N
I
T
V
T
K
E
L
L
K
Site 27
T194
I
T
L
R
L
W
N
T
K
D
K
M
S
R
K
Site 28
Y204
K
M
S
R
K
V
R
Y
Y
R
L
K
T
A
G
Site 29
Y205
M
S
R
K
V
R
Y
Y
R
L
K
T
A
G
F
Site 30
T209
V
R
Y
Y
R
L
K
T
A
G
F
T
D
D
V
Site 31
S235
V
L
N
Q
R
K
L
S
E
Q
G
I
E
N
T
Site 32
S249
T
N
I
V
R
E
E
S
N
Q
E
H
P
P
G
Site 33
S267
K
T
E
K
H
P
K
S
L
Q
G
S
H
Q
A
Site 34
S271
H
P
K
S
L
Q
G
S
H
Q
A
E
P
E
T
Site 35
T278
S
H
Q
A
E
P
E
T
S
S
K
N
S
E
E
Site 36
S279
H
Q
A
E
P
E
T
S
S
K
N
S
E
E
Y
Site 37
S283
P
E
T
S
S
K
N
S
E
E
Y
E
K
S
L
Site 38
S289
N
S
E
E
Y
E
K
S
L
K
M
D
D
S
S
Site 39
S295
K
S
L
K
M
D
D
S
S
T
I
Q
W
S
V
Site 40
S296
S
L
K
M
D
D
S
S
T
I
Q
W
S
V
S
Site 41
T297
L
K
M
D
D
S
S
T
I
Q
W
S
V
S
R
Site 42
S301
D
S
S
T
I
Q
W
S
V
S
R
T
P
T
I
Site 43
S303
S
T
I
Q
W
S
V
S
R
T
P
T
I
S
L
Site 44
S324
E
I
K
E
L
I
E
S
E
S
L
S
S
L
T
Site 45
S326
K
E
L
I
E
S
E
S
L
S
S
L
T
N
I
Site 46
S329
I
E
S
E
S
L
S
S
L
T
N
I
L
D
R
Site 47
S339
N
I
L
D
R
Q
R
S
Q
I
K
G
K
D
S
Site 48
S346
S
Q
I
K
G
K
D
S
E
G
R
R
K
I
Q
Site 49
T368
A
E
E
E
A
D
P
T
L
T
G
P
R
K
Q
Site 50
T370
E
E
A
D
P
T
L
T
G
P
R
K
Q
S
A
Site 51
S376
L
T
G
P
R
K
Q
S
A
F
S
I
Q
L
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation