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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HEG1
Full Name:
Protein HEG homolog 1 precursor
Alias:
HEG; HEG 1; KIAA1237
Type:
Uncharacterized protein
Mass (Da):
147461
Number AA:
1381
UniProt ID:
Q9ULI3
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
S
P
R
A
S
R
W
P
P
P
L
L
Site 2
T67
P
E
R
E
P
P
P
T
P
P
R
E
R
R
G
Site 3
T356
S
L
G
P
V
S
K
T
E
G
F
P
K
D
S
Site 4
S800
S
K
S
P
S
L
V
S
L
P
T
E
S
T
K
Site 5
T803
P
S
L
V
S
L
P
T
E
S
T
K
A
V
T
Site 6
S813
T
K
A
V
T
T
N
S
P
L
P
P
S
L
T
Site 7
T875
T
G
P
I
A
V
Q
T
T
A
G
K
Q
L
S
Site 8
T876
G
P
I
A
V
Q
T
T
A
G
K
Q
L
S
L
Site 9
S1281
R
K
N
K
N
D
I
S
K
L
I
F
K
S
G
Site 10
S1287
I
S
K
L
I
F
K
S
G
D
F
Q
M
S
P
Site 11
S1293
K
S
G
D
F
Q
M
S
P
Y
A
E
Y
P
K
Site 12
Y1295
G
D
F
Q
M
S
P
Y
A
E
Y
P
K
N
P
Site 13
Y1298
Q
M
S
P
Y
A
E
Y
P
K
N
P
R
S
Q
Site 14
S1304
E
Y
P
K
N
P
R
S
Q
E
W
G
R
E
A
Site 15
T1320
E
M
H
E
N
G
S
T
K
N
L
L
Q
M
T
Site 16
Y1330
L
L
Q
M
T
D
V
Y
Y
S
P
T
S
V
R
Site 17
Y1331
L
Q
M
T
D
V
Y
Y
S
P
T
S
V
R
N
Site 18
S1332
Q
M
T
D
V
Y
Y
S
P
T
S
V
R
N
P
Site 19
S1335
D
V
Y
Y
S
P
T
S
V
R
N
P
E
L
E
Site 20
Y1347
E
L
E
R
N
G
L
Y
P
A
Y
T
G
L
P
Site 21
Y1350
R
N
G
L
Y
P
A
Y
T
G
L
P
G
S
R
Site 22
T1351
N
G
L
Y
P
A
Y
T
G
L
P
G
S
R
H
Site 23
S1356
A
Y
T
G
L
P
G
S
R
H
S
C
I
F
P
Site 24
S1359
G
L
P
G
S
R
H
S
C
I
F
P
G
Q
Y
Site 25
Y1366
S
C
I
F
P
G
Q
Y
N
P
S
F
I
S
D
Site 26
S1369
F
P
G
Q
Y
N
P
S
F
I
S
D
E
S
R
Site 27
S1372
Q
Y
N
P
S
F
I
S
D
E
S
R
R
R
D
Site 28
S1375
P
S
F
I
S
D
E
S
R
R
R
D
Y
F
_
Site 29
Y1380
D
E
S
R
R
R
D
Y
F
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation