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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RAI17
Full Name:
Zinc finger MIZ domain-containing protein 1
Alias:
PIAS-like hZimp10; PIAS-like Zimp10; Retinoic acid induced 17; Retinoic acid-induced 17; ZIMP10; Zinc finger-containing, Miz1, PIAS-like protein on chromosome 10; ZMIZ1
Type:
Nuclear speck, Cytoplasm, Nucleus protein
Mass (Da):
115483
Number AA:
1067
UniProt ID:
Q9ULJ6
International Prot ID:
IPI00176571
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0016607
Uniprot
OncoNet
Molecular Function:
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T89
A
A
N
R
D
K
F
T
P
K
S
A
A
L
L
Site 2
S92
R
D
K
F
T
P
K
S
A
A
L
L
S
S
W
Site 3
S97
P
K
S
A
A
L
L
S
S
W
C
E
E
L
G
Site 4
S98
K
S
A
A
L
L
S
S
W
C
E
E
L
G
R
Site 5
S114
L
L
L
R
H
Q
K
S
R
Q
S
D
P
P
G
Site 6
S117
R
H
Q
K
S
R
Q
S
D
P
P
G
K
L
P
Site 7
S130
L
P
M
Q
P
P
L
S
S
M
S
S
M
K
P
Site 8
S131
P
M
Q
P
P
L
S
S
M
S
S
M
K
P
T
Site 9
S133
Q
P
P
L
S
S
M
S
S
M
K
P
T
L
S
Site 10
S134
P
P
L
S
S
M
S
S
M
K
P
T
L
S
H
Site 11
T138
S
M
S
S
M
K
P
T
L
S
H
S
D
G
S
Site 12
S140
S
S
M
K
P
T
L
S
H
S
D
G
S
F
P
Site 13
S142
M
K
P
T
L
S
H
S
D
G
S
F
P
Y
D
Site 14
S145
T
L
S
H
S
D
G
S
F
P
Y
D
S
V
P
Site 15
Y148
H
S
D
G
S
F
P
Y
D
S
V
P
W
Q
Q
Site 16
T157
S
V
P
W
Q
Q
N
T
N
Q
P
P
G
S
L
Site 17
S163
N
T
N
Q
P
P
G
S
L
S
V
V
T
T
V
Site 18
S165
N
Q
P
P
G
S
L
S
V
V
T
T
V
W
G
Site 19
S177
V
W
G
V
T
N
T
S
Q
S
Q
V
L
G
N
Site 20
S179
G
V
T
N
T
S
Q
S
Q
V
L
G
N
P
M
Site 21
S202
P
G
G
N
P
M
A
S
G
M
T
T
S
N
P
Site 22
T206
P
M
A
S
G
M
T
T
S
N
P
G
L
N
S
Site 23
S207
M
A
S
G
M
T
T
S
N
P
G
L
N
S
P
Site 24
S213
T
S
N
P
G
L
N
S
P
Q
F
A
G
Q
Q
Site 25
S224
A
G
Q
Q
Q
Q
F
S
A
K
A
G
P
A
Q
Site 26
Y233
K
A
G
P
A
Q
P
Y
I
Q
Q
S
M
Y
G
Site 27
Y239
P
Y
I
Q
Q
S
M
Y
G
R
P
N
Y
P
G
Site 28
Y244
S
M
Y
G
R
P
N
Y
P
G
S
G
G
F
G
Site 29
S247
G
R
P
N
Y
P
G
S
G
G
F
G
A
S
Y
Site 30
S253
G
S
G
G
F
G
A
S
Y
P
G
G
P
N
A
Site 31
Y254
S
G
G
F
G
A
S
Y
P
G
G
P
N
A
P
Site 32
T270
G
M
G
I
P
P
H
T
R
P
P
A
D
F
T
Site 33
Y317
Q
N
K
D
I
N
Q
Y
G
P
M
G
P
T
Q
Site 34
Y326
P
M
G
P
T
Q
A
Y
N
S
Q
F
M
N
Q
Site 35
S328
G
P
T
Q
A
Y
N
S
Q
F
M
N
Q
P
G
Site 36
S341
P
G
P
R
G
P
A
S
M
G
G
S
M
N
P
Site 37
S345
G
P
A
S
M
G
G
S
M
N
P
A
S
M
A
Site 38
S350
G
G
S
M
N
P
A
S
M
A
A
G
M
T
P
Site 39
S361
G
M
T
P
S
G
M
S
G
P
P
M
G
M
N
Site 40
S376
Q
P
R
P
P
G
I
S
P
F
G
T
H
G
Q
Site 41
T380
P
G
I
S
P
F
G
T
H
G
Q
R
M
P
Q
Site 42
T389
G
Q
R
M
P
Q
Q
T
Y
P
G
P
R
P
Q
Site 43
Y390
Q
R
M
P
Q
Q
T
Y
P
G
P
R
P
Q
S
Site 44
S397
Y
P
G
P
R
P
Q
S
L
P
I
Q
N
I
K
Site 45
Y407
I
Q
N
I
K
R
P
Y
P
G
E
P
N
Y
G
Site 46
Y413
P
Y
P
G
E
P
N
Y
G
N
Q
Q
Y
G
P
Site 47
Y418
P
N
Y
G
N
Q
Q
Y
G
P
N
S
Q
F
P
Site 48
S422
N
Q
Q
Y
G
P
N
S
Q
F
P
T
Q
P
G
Site 49
T426
G
P
N
S
Q
F
P
T
Q
P
G
Q
Y
P
A
Site 50
Y431
F
P
T
Q
P
G
Q
Y
P
A
P
N
P
P
R
Site 51
T441
P
N
P
P
R
P
L
T
S
P
N
Y
P
G
Q
Site 52
S442
N
P
P
R
P
L
T
S
P
N
Y
P
G
Q
R
Site 53
Y445
R
P
L
T
S
P
N
Y
P
G
Q
R
M
P
S
Site 54
S452
Y
P
G
Q
R
M
P
S
Q
P
S
S
G
Q
Y
Site 55
S456
R
M
P
S
Q
P
S
S
G
Q
Y
P
P
P
T
Site 56
Y459
S
Q
P
S
S
G
Q
Y
P
P
P
T
V
N
M
Site 57
T463
S
G
Q
Y
P
P
P
T
V
N
M
G
Q
Y
Y
Site 58
Y469
P
T
V
N
M
G
Q
Y
Y
K
P
E
Q
F
N
Site 59
T481
Q
F
N
G
Q
N
N
T
F
S
G
S
S
Y
S
Site 60
S483
N
G
Q
N
N
T
F
S
G
S
S
Y
S
N
Y
Site 61
S485
Q
N
N
T
F
S
G
S
S
Y
S
N
Y
S
Q
Site 62
S486
N
N
T
F
S
G
S
S
Y
S
N
Y
S
Q
G
Site 63
Y487
N
T
F
S
G
S
S
Y
S
N
Y
S
Q
G
N
Site 64
S488
T
F
S
G
S
S
Y
S
N
Y
S
Q
G
N
V
Site 65
Y490
S
G
S
S
Y
S
N
Y
S
Q
G
N
V
N
R
Site 66
S491
G
S
S
Y
S
N
Y
S
Q
G
N
V
N
R
P
Site 67
Y507
R
P
V
P
V
A
N
Y
P
H
S
P
V
P
G
Site 68
S510
P
V
A
N
Y
P
H
S
P
V
P
G
N
P
T
Site 69
T517
S
P
V
P
G
N
P
T
P
P
M
T
P
G
S
Site 70
T521
G
N
P
T
P
P
M
T
P
G
S
S
I
P
P
Site 71
S524
T
P
P
M
T
P
G
S
S
I
P
P
Y
L
S
Site 72
S525
P
P
M
T
P
G
S
S
I
P
P
Y
L
S
P
Site 73
Y529
P
G
S
S
I
P
P
Y
L
S
P
S
Q
D
V
Site 74
S531
S
S
I
P
P
Y
L
S
P
S
Q
D
V
K
P
Site 75
S533
I
P
P
Y
L
S
P
S
Q
D
V
K
P
P
F
Site 76
S549
P
D
I
K
P
N
M
S
A
L
P
P
P
P
A
Site 77
T565
H
N
D
E
L
R
L
T
F
P
V
R
D
G
V
Site 78
T599
L
R
P
T
V
H
Q
T
L
M
W
R
S
D
L
Site 79
T638
S
V
N
A
T
P
L
T
I
E
R
G
D
N
K
Site 80
T646
I
E
R
G
D
N
K
T
S
H
K
P
L
H
L
Site 81
S686
L
Q
L
V
H
R
P
S
V
R
S
V
L
Q
G
Site 82
S689
V
H
R
P
S
V
R
S
V
L
Q
G
L
L
K
Site 83
T707
L
P
A
E
H
C
I
T
K
I
K
R
N
F
S
Site 84
S714
T
K
I
K
R
N
F
S
S
V
A
A
S
S
G
Site 85
S715
K
I
K
R
N
F
S
S
V
A
A
S
S
G
N
Site 86
S719
N
F
S
S
V
A
A
S
S
G
N
T
T
L
N
Site 87
S720
F
S
S
V
A
A
S
S
G
N
T
T
L
N
G
Site 88
T724
A
A
S
S
G
N
T
T
L
N
G
E
D
G
V
Site 89
Y798
E
G
L
E
V
D
Q
Y
M
W
G
I
L
N
A
Site 90
T819
E
E
V
T
I
D
P
T
C
S
W
R
P
V
P
Site 91
S829
W
R
P
V
P
I
K
S
D
L
H
I
K
D
D
Site 92
S842
D
D
P
D
G
I
P
S
K
R
F
K
T
M
S
Site 93
T847
I
P
S
K
R
F
K
T
M
S
P
S
Q
M
I
Site 94
S849
S
K
R
F
K
T
M
S
P
S
Q
M
I
M
P
Site 95
S870
A
A
L
G
P
G
P
S
P
Y
P
L
P
P
P
Site 96
Y872
L
G
P
G
P
S
P
Y
P
L
P
P
P
P
G
Site 97
S883
P
P
P
G
G
T
N
S
N
D
Y
S
S
Q
G
Site 98
Y886
G
G
T
N
S
N
D
Y
S
S
Q
G
N
N
Y
Site 99
S887
G
T
N
S
N
D
Y
S
S
Q
G
N
N
Y
Q
Site 100
S888
T
N
S
N
D
Y
S
S
Q
G
N
N
Y
Q
G
Site 101
Y893
Y
S
S
Q
G
N
N
Y
Q
G
H
G
N
F
D
Site 102
S922
M
H
G
P
P
Q
L
S
H
P
P
D
M
P
N
Site 103
S939
A
A
L
E
K
P
L
S
H
P
M
Q
E
T
M
Site 104
S952
T
M
P
H
A
G
S
S
D
Q
P
H
P
S
I
Site 105
S958
S
S
D
Q
P
H
P
S
I
Q
Q
G
L
H
V
Site 106
S969
G
L
H
V
P
H
P
S
S
Q
S
G
P
P
L
Site 107
S970
L
H
V
P
H
P
S
S
Q
S
G
P
P
L
H
Site 108
S972
V
P
H
P
S
S
Q
S
G
P
P
L
H
H
S
Site 109
S979
S
G
P
P
L
H
H
S
G
A
P
P
P
P
P
Site 110
S987
G
A
P
P
P
P
P
S
Q
P
P
R
Q
P
P
Site 111
S999
Q
P
P
Q
A
A
P
S
S
H
P
H
S
D
L
Site 112
S1000
P
P
Q
A
A
P
S
S
H
P
H
S
D
L
T
Site 113
S1004
A
P
S
S
H
P
H
S
D
L
T
F
N
P
S
Site 114
T1007
S
H
P
H
S
D
L
T
F
N
P
S
S
A
L
Site 115
S1011
S
D
L
T
F
N
P
S
S
A
L
E
G
Q
A
Site 116
S1012
D
L
T
F
N
P
S
S
A
L
E
G
Q
A
G
Site 117
S1024
Q
A
G
A
Q
G
A
S
D
M
P
E
P
S
L
Site 118
S1030
A
S
D
M
P
E
P
S
L
D
L
L
P
E
L
Site 119
T1038
L
D
L
L
P
E
L
T
N
P
D
E
L
L
S
Site 120
S1045
T
N
P
D
E
L
L
S
Y
L
D
P
P
D
L
Site 121
Y1046
N
P
D
E
L
L
S
Y
L
D
P
P
D
L
P
Site 122
S1054
L
D
P
P
D
L
P
S
N
S
N
D
D
L
L
Site 123
S1056
P
P
D
L
P
S
N
S
N
D
D
L
L
S
L
Site 124
S1062
N
S
N
D
D
L
L
S
L
F
E
N
N
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation