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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
VANGL2
Full Name:
Vang-like protein 2
Alias:
KIAA1215; Loop-tail protein 1; Loop-tail-associated protein; LPP1; LTAP; MGC119403; MGC119404; STB1; STBM; STBM1; Strabismus; Strabismus 1; Van gogh; Van Gogh-like protein 2; Vang, van gogh-like 2; VANG2; Vang-like 2
Type:
Adaptor/scaffold
Mass (Da):
59714
Number AA:
521
UniProt ID:
Q9ULK5
International Prot ID:
IPI00029449
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0045176
GO:0001736
GO:0001947
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
D
T
E
S
Q
Y
S
G
Y
S
Y
Site 2
S8
M
D
T
E
S
Q
Y
S
G
Y
S
Y
K
S
G
Site 3
Y10
T
E
S
Q
Y
S
G
Y
S
Y
K
S
G
H
S
Site 4
S11
E
S
Q
Y
S
G
Y
S
Y
K
S
G
H
S
R
Site 5
Y12
S
Q
Y
S
G
Y
S
Y
K
S
G
H
S
R
S
Site 6
S14
Y
S
G
Y
S
Y
K
S
G
H
S
R
S
S
R
Site 7
S17
Y
S
Y
K
S
G
H
S
R
S
S
R
K
H
R
Site 8
S19
Y
K
S
G
H
S
R
S
S
R
K
H
R
D
R
Site 9
S20
K
S
G
H
S
R
S
S
R
K
H
R
D
R
R
Site 10
S32
D
R
R
D
R
H
R
S
K
S
R
D
G
G
R
Site 11
S34
R
D
R
H
R
S
K
S
R
D
G
G
R
G
D
Site 12
S43
D
G
G
R
G
D
K
S
V
T
I
Q
A
P
G
Site 13
S58
E
P
L
L
D
N
E
S
T
R
G
D
E
R
D
Site 14
T73
D
N
W
G
E
T
T
T
V
V
T
G
T
S
E
Site 15
S82
V
T
G
T
S
E
H
S
I
S
H
D
D
L
T
Site 16
S84
G
T
S
E
H
S
I
S
H
D
D
L
T
R
I
Site 17
T89
S
I
S
H
D
D
L
T
R
I
A
K
D
M
E
Site 18
S98
I
A
K
D
M
E
D
S
V
P
L
D
C
S
R
Site 19
S211
I
L
D
A
R
E
R
S
Y
Q
G
V
V
Q
F
Site 20
Y212
L
D
A
R
E
R
S
Y
Q
G
V
V
Q
F
A
Site 21
T247
R
Q
L
Q
P
Q
F
T
L
K
V
V
R
S
T
Site 22
S253
F
T
L
K
V
V
R
S
T
D
G
A
S
R
F
Site 23
T254
T
L
K
V
V
R
S
T
D
G
A
S
R
F
Y
Site 24
Y261
T
D
G
A
S
R
F
Y
N
V
G
H
L
S
I
Site 25
Y286
Y
Y
H
D
F
P
V
Y
N
P
A
L
L
N
L
Site 26
Y308
K
V
S
G
F
K
V
Y
S
L
G
E
E
N
S
Site 27
S309
V
S
G
F
K
V
Y
S
L
G
E
E
N
S
T
Site 28
S315
Y
S
L
G
E
E
N
S
T
N
N
S
T
G
Q
Site 29
T316
S
L
G
E
E
N
S
T
N
N
S
T
G
Q
S
Site 30
S319
E
E
N
S
T
N
N
S
T
G
Q
S
R
A
V
Site 31
S323
T
N
N
S
T
G
Q
S
R
A
V
I
A
A
A
Site 32
S337
A
A
R
R
R
D
N
S
H
N
E
Y
Y
Y
E
Site 33
Y341
R
D
N
S
H
N
E
Y
Y
Y
E
E
A
E
H
Site 34
Y342
D
N
S
H
N
E
Y
Y
Y
E
E
A
E
H
E
Site 35
Y343
N
S
H
N
E
Y
Y
Y
E
E
A
E
H
E
R
Site 36
T368
V
A
V
E
E
A
F
T
H
I
K
R
L
Q
E
Site 37
Y405
M
A
R
A
M
Q
K
Y
L
R
T
T
K
Q
Q
Site 38
T409
M
Q
K
Y
L
R
T
T
K
Q
Q
P
Y
H
T
Site 39
Y414
R
T
T
K
Q
Q
P
Y
H
T
M
E
S
I
L
Site 40
T433
F
C
I
T
H
D
M
T
P
K
A
F
L
E
R
Site 41
T461
R
W
L
A
K
Q
W
T
L
V
S
E
E
P
V
Site 42
S464
A
K
Q
W
T
L
V
S
E
E
P
V
T
N
G
Site 43
T469
L
V
S
E
E
P
V
T
N
G
L
K
D
G
I
Site 44
S486
L
L
K
R
Q
D
F
S
L
V
V
S
T
K
K
Site 45
S508
E
E
F
V
D
P
K
S
H
K
F
V
M
R
L
Site 46
S517
K
F
V
M
R
L
Q
S
E
T
S
V
_
_
_
Site 47
T519
V
M
R
L
Q
S
E
T
S
V
_
_
_
_
_
Site 48
S520
M
R
L
Q
S
E
T
S
V
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation