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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PNMAL2
Full Name:
Alias:
Type:
Mass (Da):
68844
Number AA:
637
UniProt ID:
Q9ULN7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
L
L
Q
D
W
C
R
S
L
D
V
D
A
H
R
Site 2
T48
P
T
L
L
P
L
G
T
F
R
L
R
H
M
K
Site 3
T116
L
L
L
D
D
G
P
T
Q
A
A
E
A
G
T
Site 4
T123
T
Q
A
A
E
A
G
T
P
G
E
A
P
T
P
Site 5
T129
G
T
P
G
E
A
P
T
P
P
A
S
E
T
Q
Site 6
S133
E
A
P
T
P
P
A
S
E
T
Q
A
Q
D
S
Site 7
S140
S
E
T
Q
A
Q
D
S
G
E
V
T
G
Q
A
Site 8
T144
A
Q
D
S
G
E
V
T
G
Q
A
G
S
L
L
Site 9
S149
E
V
T
G
Q
A
G
S
L
L
G
A
A
R
N
Site 10
T168
R
R
G
R
R
N
R
T
R
R
N
R
L
T
Q
Site 11
T174
R
T
R
R
N
R
L
T
Q
K
G
K
K
R
S
Site 12
S181
T
Q
K
G
K
K
R
S
R
G
G
R
P
S
A
Site 13
S187
R
S
R
G
G
R
P
S
A
P
A
R
S
E
A
Site 14
S192
R
P
S
A
P
A
R
S
E
A
E
D
S
S
D
Site 15
S197
A
R
S
E
A
E
D
S
S
D
E
S
L
G
I
Site 16
S198
R
S
E
A
E
D
S
S
D
E
S
L
G
I
V
Site 17
S201
A
E
D
S
S
D
E
S
L
G
I
V
I
E
E
Site 18
S215
E
I
D
Q
G
D
L
S
G
E
E
D
Q
S
A
Site 19
S221
L
S
G
E
E
D
Q
S
A
L
Y
A
T
L
Q
Site 20
S243
R
Q
W
A
P
C
N
S
E
G
E
E
D
G
P
Site 21
T258
R
E
F
L
A
L
V
T
V
T
D
K
S
K
K
Site 22
S263
L
V
T
V
T
D
K
S
K
K
E
E
A
E
K
Site 23
S277
K
E
P
A
G
A
E
S
I
R
L
N
T
K
E
Site 24
T282
A
E
S
I
R
L
N
T
K
E
D
K
N
G
V
Site 25
T301
A
L
L
A
V
R
D
T
P
D
E
E
P
V
D
Site 26
S309
P
D
E
E
P
V
D
S
D
T
S
E
S
D
S
Site 27
T311
E
E
P
V
D
S
D
T
S
E
S
D
S
Q
E
Site 28
S312
E
P
V
D
S
D
T
S
E
S
D
S
Q
E
S
Site 29
S314
V
D
S
D
T
S
E
S
D
S
Q
E
S
G
D
Site 30
S316
S
D
T
S
E
S
D
S
Q
E
S
G
D
Q
E
Site 31
S342
I
V
A
Y
T
D
P
S
D
P
W
A
R
E
E
Site 32
S359
K
I
A
S
V
I
E
S
L
G
W
S
D
E
K
Site 33
S363
V
I
E
S
L
G
W
S
D
E
K
D
K
R
D
Site 34
S377
D
P
L
R
Q
V
L
S
V
M
S
K
D
T
N
Site 35
S416
G
D
L
R
E
C
I
S
T
L
A
Q
P
D
L
Site 36
T417
D
L
R
E
C
I
S
T
L
A
Q
P
D
L
P
Site 37
S439
R
G
L
F
G
G
W
S
E
H
R
E
D
E
G
Site 38
Y477
N
A
W
E
G
G
K
Y
K
Y
P
K
G
K
L
Site 39
Y479
W
E
G
G
K
Y
K
Y
P
K
G
K
L
G
E
Site 40
S499
A
A
R
E
N
M
G
S
N
E
G
S
E
E
A
Site 41
S503
N
M
G
S
N
E
G
S
E
E
A
S
D
E
Q
Site 42
S507
N
E
G
S
E
E
A
S
D
E
Q
S
E
E
E
Site 43
S511
E
E
A
S
D
E
Q
S
E
E
E
S
E
D
T
Site 44
S515
D
E
Q
S
E
E
E
S
E
D
T
E
S
E
A
Site 45
T518
S
E
E
E
S
E
D
T
E
S
E
A
S
E
P
Site 46
S520
E
E
S
E
D
T
E
S
E
A
S
E
P
E
D
Site 47
S523
E
D
T
E
S
E
A
S
E
P
E
D
R
A
S
Site 48
S530
S
E
P
E
D
R
A
S
R
K
P
R
A
K
R
Site 49
T540
P
R
A
K
R
A
R
T
A
P
R
G
L
T
P
Site 50
T546
R
T
A
P
R
G
L
T
P
A
G
A
P
P
T
Site 51
S555
A
G
A
P
P
T
A
S
G
A
R
K
T
R
A
Site 52
T560
T
A
S
G
A
R
K
T
R
A
G
G
R
G
R
Site 53
T574
R
G
R
G
R
G
V
T
P
E
K
K
A
G
S
Site 54
S584
K
K
A
G
S
R
G
S
A
Q
D
D
A
A
G
Site 55
S592
A
Q
D
D
A
A
G
S
R
K
K
K
G
S
A
Site 56
S598
G
S
R
K
K
K
G
S
A
G
S
G
A
H
A
Site 57
S618
K
G
Q
A
P
T
G
S
K
A
A
R
G
K
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation