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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ISY1
Full Name:
Pre-mRNA-splicing factor ISY1 homolog
Alias:
FSAP33; Functional spliceosome-associated protein 33; ISY1 splicing factor; KIAA1160; Pre-mRNA-splicing factor ISY1
Type:
Unknown function
Mass (Da):
37567
Number AA:
331
UniProt ID:
Q9ULR0
International Prot ID:
IPI00744858
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005681
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0008380
GO:0006397
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
R
N
A
E
K
A
M
T
A
L
A
R
F
R
Q
Site 2
S34
E
R
R
P
F
L
A
S
E
C
T
E
L
P
K
Site 3
T37
P
F
L
A
S
E
C
T
E
L
P
K
A
E
K
Site 4
Y99
K
E
L
G
G
P
D
Y
G
K
V
G
P
K
M
Site 5
Y120
E
V
P
G
N
R
G
Y
K
Y
F
G
A
A
K
Site 6
Y122
P
G
N
R
G
Y
K
Y
F
G
A
A
K
D
L
Site 7
T147
P
L
P
P
P
R
K
T
R
A
E
L
M
K
A
Site 8
Y159
M
K
A
I
D
F
E
Y
Y
G
Y
L
D
E
D
Site 9
Y162
I
D
F
E
Y
Y
G
Y
L
D
E
D
D
G
V
Site 10
Y215
E
E
E
E
I
N
I
Y
A
V
T
E
E
E
S
Site 11
S222
Y
A
V
T
E
E
E
S
D
E
E
G
S
Q
E
Site 12
S227
E
E
S
D
E
E
G
S
Q
E
K
G
G
D
D
Site 13
S235
Q
E
K
G
G
D
D
S
Q
Q
K
F
I
A
H
Site 14
S247
I
A
H
V
P
V
P
S
Q
Q
E
I
E
E
A
Site 15
Y267
K
M
E
L
L
Q
K
Y
A
S
E
T
L
Q
A
Site 16
S269
E
L
L
Q
K
Y
A
S
E
T
L
Q
A
Q
S
Site 17
S287
R
R
L
L
G
C
R
S
G
T
R
P
A
R
S
Site 18
T289
L
L
G
C
R
S
G
T
R
P
A
R
S
G
S
Site 19
S294
S
G
T
R
P
A
R
S
G
S
A
P
S
P
R
Site 20
S296
T
R
P
A
R
S
G
S
A
P
S
P
R
A
T
Site 21
S299
A
R
S
G
S
A
P
S
P
R
A
T
T
A
V
Site 22
T303
S
A
P
S
P
R
A
T
T
A
V
P
M
G
P
Site 23
T304
A
P
S
P
R
A
T
T
A
V
P
M
G
P
S
Site 24
S311
T
A
V
P
M
G
P
S
L
P
T
T
S
P
R
Site 25
T314
P
M
G
P
S
L
P
T
T
S
P
R
G
A
P
Site 26
T315
M
G
P
S
L
P
T
T
S
P
R
G
A
P
S
Site 27
S316
G
P
S
L
P
T
T
S
P
R
G
A
P
S
C
Site 28
S322
T
S
P
R
G
A
P
S
C
R
C
L
T
G
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation