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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TMCC3
Full Name:
Transmembrane and coiled-coil domains protein 3
Alias:
Transmembrane and coiled-coil domain family 3; Transmembrane and coiled-coil domains 3
Type:
Uncharacterized protein
Mass (Da):
53768
Number AA:
477
UniProt ID:
Q9ULS5
International Prot ID:
IPI00240059
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
P
G
S
D
T
A
L
T
V
D
R
T
Y
S
D
Site 2
T13
T
A
L
T
V
D
R
T
Y
S
D
P
G
R
H
Site 3
Y14
A
L
T
V
D
R
T
Y
S
D
P
G
R
H
H
Site 4
S15
L
T
V
D
R
T
Y
S
D
P
G
R
H
H
R
Site 5
S25
G
R
H
H
R
C
K
S
R
V
E
R
H
D
M
Site 6
T34
V
E
R
H
D
M
N
T
L
S
L
P
L
N
I
Site 7
S36
R
H
D
M
N
T
L
S
L
P
L
N
I
R
R
Site 8
S46
L
N
I
R
R
G
G
S
D
T
N
L
N
F
D
Site 9
T48
I
R
R
G
G
S
D
T
N
L
N
F
D
V
P
Site 10
Y96
R
D
G
N
V
A
E
Y
L
K
L
V
N
N
A
Site 11
S122
F
E
K
K
N
Q
K
S
A
H
S
I
A
Q
L
Site 12
Y136
L
Q
K
K
L
E
Q
Y
H
R
K
L
R
E
I
Site 13
S149
E
I
E
Q
N
G
A
S
R
S
S
K
D
I
S
Site 14
S151
E
Q
N
G
A
S
R
S
S
K
D
I
S
K
D
Site 15
S152
Q
N
G
A
S
R
S
S
K
D
I
S
K
D
H
Site 16
S156
S
R
S
S
K
D
I
S
K
D
H
L
K
D
I
Site 17
S183
T
A
P
H
C
M
E
S
S
K
S
G
M
P
G
Site 18
S184
A
P
H
C
M
E
S
S
K
S
G
M
P
G
V
Site 19
S186
H
C
M
E
S
S
K
S
G
M
P
G
V
S
L
Site 20
S216
L
I
R
N
K
F
G
S
A
D
N
I
A
H
L
Site 21
S226
N
I
A
H
L
K
N
S
L
E
E
F
R
Q
E
Site 22
S235
E
E
F
R
Q
E
A
S
A
R
A
Y
G
G
S
Site 23
Y239
Q
E
A
S
A
R
A
Y
G
G
S
A
T
I
V
Site 24
S242
S
A
R
A
Y
G
G
S
A
T
I
V
N
K
P
Site 25
T244
R
A
Y
G
G
S
A
T
I
V
N
K
P
K
Y
Site 26
Y251
T
I
V
N
K
P
K
Y
G
S
D
D
E
C
S
Site 27
S253
V
N
K
P
K
Y
G
S
D
D
E
C
S
S
G
Site 28
S258
Y
G
S
D
D
E
C
S
S
G
T
S
G
S
A
Site 29
S259
G
S
D
D
E
C
S
S
G
T
S
G
S
A
D
Site 30
S262
D
E
C
S
S
G
T
S
G
S
A
D
S
N
G
Site 31
S264
C
S
S
G
T
S
G
S
A
D
S
N
G
N
Q
Site 32
S267
G
T
S
G
S
A
D
S
N
G
N
Q
S
F
G
Site 33
S272
A
D
S
N
G
N
Q
S
F
G
A
G
G
A
S
Site 34
S279
S
F
G
A
G
G
A
S
T
L
D
S
Q
G
K
Site 35
T280
F
G
A
G
G
A
S
T
L
D
S
Q
G
K
L
Site 36
T300
E
L
R
E
I
K
D
T
Q
A
Q
L
A
E
D
Site 37
Y319
K
V
Q
F
K
R
E
Y
G
F
I
S
Q
T
L
Site 38
S323
K
R
E
Y
G
F
I
S
Q
T
L
Q
E
E
R
Site 39
T325
E
Y
G
F
I
S
Q
T
L
Q
E
E
R
Y
R
Site 40
Y333
L
Q
E
E
R
Y
R
Y
E
R
L
E
D
Q
L
Site 41
T344
E
D
Q
L
H
D
L
T
D
L
H
Q
H
E
T
Site 42
Y367
S
I
E
E
K
V
A
Y
Q
A
Y
E
R
S
R
Site 43
Y370
E
K
V
A
Y
Q
A
Y
E
R
S
R
D
I
Q
Site 44
S382
D
I
Q
E
A
L
E
S
C
Q
T
R
I
S
K
Site 45
T385
E
A
L
E
S
C
Q
T
R
I
S
K
L
E
L
Site 46
S388
E
S
C
Q
T
R
I
S
K
L
E
L
H
Q
Q
Site 47
S437
S
T
I
A
K
F
V
S
P
M
M
K
S
R
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation