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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TTC7A
Full Name:
ISOFORM 2 OF TETRATRICOPEPTIDE REPEAT PROTEIN 7A.
Alias:
KIAA1140; Tetratricopeptide repeat domain 7A; Tetratricopeptide repeat protein 7A; TPR repeat protein 7; TTC7
Type:
Mass (Da):
96185
Number AA:
858
UniProt ID:
Q9ULT0
International Prot ID:
IPI00397195
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
A
A
K
G
A
H
G
S
Y
L
K
V
E
S
E
Site 2
Y10
A
K
G
A
H
G
S
Y
L
K
V
E
S
E
L
Site 3
T38
E
L
V
R
Q
L
Q
T
L
S
M
P
G
G
G
Site 4
S40
V
R
Q
L
Q
T
L
S
M
P
G
G
G
G
N
Site 5
S51
G
G
G
N
R
R
G
S
P
S
A
A
F
T
F
Site 6
S53
G
N
R
R
G
S
P
S
A
A
F
T
F
P
D
Site 7
T57
G
S
P
S
A
A
F
T
F
P
D
T
D
D
F
Site 8
S100
E
K
N
E
P
K
M
S
E
A
K
N
Y
L
S
Site 9
Y105
K
M
S
E
A
K
N
Y
L
S
S
I
L
N
H
Site 10
S116
I
L
N
H
G
R
L
S
P
Q
Y
M
C
E
A
Site 11
Y132
L
I
L
G
K
L
H
Y
V
E
G
S
Y
R
D
Site 12
S136
K
L
H
Y
V
E
G
S
Y
R
D
A
I
S
M
Site 13
S142
G
S
Y
R
D
A
I
S
M
Y
A
R
A
G
I
Site 14
Y144
Y
R
D
A
I
S
M
Y
A
R
A
G
I
D
D
Site 15
S153
R
A
G
I
D
D
M
S
M
E
N
K
P
L
Y
Site 16
Y160
S
M
E
N
K
P
L
Y
Q
M
R
L
L
S
E
Site 17
S182
S
L
E
R
L
P
N
S
I
A
S
R
F
R
L
Site 18
T190
I
A
S
R
F
R
L
T
E
R
E
E
E
V
I
Site 19
T198
E
R
E
E
E
V
I
T
C
F
E
R
A
S
W
Site 20
T217
F
L
Q
E
L
E
K
T
T
N
N
S
T
S
R
Site 21
S221
L
E
K
T
T
N
N
S
T
S
R
H
L
K
G
Site 22
Y234
K
G
C
H
P
L
D
Y
E
L
T
Y
F
L
E
Site 23
Y248
E
A
A
L
Q
S
A
Y
V
K
N
L
K
K
G
Site 24
T270
E
L
R
E
V
L
R
T
V
E
T
K
A
T
Q
Site 25
T276
R
T
V
E
T
K
A
T
Q
N
F
K
V
M
A
Site 26
S296
G
V
L
L
H
S
L
S
E
E
C
Y
W
S
P
Site 27
Y300
H
S
L
S
E
E
C
Y
W
S
P
L
S
H
P
Site 28
S302
L
S
E
E
C
Y
W
S
P
L
S
H
P
L
P
Site 29
S318
F
M
G
K
E
E
S
S
F
A
T
Q
A
L
R
Site 30
T321
K
E
E
S
S
F
A
T
Q
A
L
R
K
P
H
Site 31
Y330
A
L
R
K
P
H
L
Y
E
G
D
N
L
Y
C
Site 32
Y336
L
Y
E
G
D
N
L
Y
C
P
K
D
N
I
E
Site 33
S363
A
T
R
D
V
V
L
S
R
V
P
E
Q
E
E
Site 34
T373
P
E
Q
E
E
D
R
T
V
S
L
Q
N
A
A
Site 35
S375
Q
E
E
D
R
T
V
S
L
Q
N
A
A
A
I
Site 36
T389
I
Y
D
L
L
S
I
T
L
G
R
R
G
Q
Y
Site 37
Y396
T
L
G
R
R
G
Q
Y
V
M
L
S
E
C
L
Site 38
S400
R
G
Q
Y
V
M
L
S
E
C
L
E
R
A
M
Site 39
S446
E
C
V
K
L
R
P
S
D
P
T
V
P
L
M
Site 40
T449
K
L
R
P
S
D
P
T
V
P
L
M
A
A
K
Site 41
T502
L
T
Y
S
L
Q
A
T
D
A
T
L
K
S
K
Site 42
S508
A
T
D
A
T
L
K
S
K
Q
D
E
L
H
R
Site 43
T520
L
H
R
K
A
L
Q
T
L
E
R
A
Q
Q
L
Site 44
S530
R
A
Q
Q
L
A
P
S
D
P
Q
V
I
L
Y
Site 45
S577
H
L
L
A
L
L
F
S
A
Q
K
H
H
Q
H
Site 46
Y634
L
R
L
W
Q
T
L
Y
S
F
S
Q
L
G
G
Site 47
S635
R
L
W
Q
T
L
Y
S
F
S
Q
L
G
G
L
Site 48
S637
W
Q
T
L
Y
S
F
S
Q
L
G
G
L
E
K
Site 49
S647
G
G
L
E
K
D
G
S
F
G
E
G
L
T
M
Site 50
T653
G
S
F
G
E
G
L
T
M
K
K
Q
S
G
M
Site 51
T663
K
Q
S
G
M
H
L
T
L
P
D
A
H
D
A
Site 52
S672
P
D
A
H
D
A
D
S
G
S
R
R
A
S
S
Site 53
S674
A
H
D
A
D
S
G
S
R
R
A
S
S
I
A
Site 54
S678
D
S
G
S
R
R
A
S
S
I
A
A
S
R
L
Site 55
S679
S
G
S
R
R
A
S
S
I
A
A
S
R
L
E
Site 56
S683
R
A
S
S
I
A
A
S
R
L
E
E
A
M
S
Site 57
S690
S
R
L
E
E
A
M
S
E
L
T
M
P
S
S
Site 58
T693
E
E
A
M
S
E
L
T
M
P
S
S
V
L
K
Site 59
S697
S
E
L
T
M
P
S
S
V
L
K
Q
G
P
M
Site 60
S746
G
L
F
P
T
S
H
S
V
L
Y
M
R
G
R
Site 61
Y749
P
T
S
H
S
V
L
Y
M
R
G
R
L
A
E
Site 62
T773
Q
L
Y
K
E
A
L
T
V
N
P
D
G
V
R
Site 63
S790
H
S
L
G
L
M
L
S
R
L
G
H
K
S
L
Site 64
S796
L
S
R
L
G
H
K
S
L
A
Q
K
V
L
R
Site 65
T811
D
A
V
E
R
Q
S
T
C
H
E
A
W
Q
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation