KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
PADI3
Full Name:
Alias:
Peptidylarginine deiminase III;Protein-arginine deiminase type III
Type:
Mass (Da):
74743
Number AA:
664
UniProt ID:
Q9ULW8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
L
Q
R
I
V
R
V
S
L
E
H
P
T
S
A
Site 2
Y51
G
T
P
G
V
D
I
Y
I
S
P
N
M
E
R
Site 3
S53
P
G
V
D
I
Y
I
S
P
N
M
E
R
G
R
Site 4
T65
R
G
R
E
R
A
D
T
R
R
W
R
F
D
A
Site 5
S82
E
I
I
V
V
M
N
S
P
S
N
D
L
N
D
Site 6
S90
P
S
N
D
L
N
D
S
H
V
Q
I
S
Y
H
Site 7
S95
N
D
S
H
V
Q
I
S
Y
H
S
S
H
E
P
Site 8
Y96
D
S
H
V
Q
I
S
Y
H
S
S
H
E
P
L
Site 9
S99
V
Q
I
S
Y
H
S
S
H
E
P
L
P
L
A
Site 10
S181
L
Q
D
L
E
D
M
S
V
M
V
L
R
T
Q
Site 11
S204
H
K
L
V
L
H
T
S
S
Y
D
A
K
R
A
Site 12
S205
K
L
V
L
H
T
S
S
Y
D
A
K
R
A
Q
Site 13
Y226
P
E
D
V
C
E
A
Y
R
H
V
L
G
Q
D
Site 14
S236
V
L
G
Q
D
K
V
S
Y
E
V
P
R
L
H
Site 15
Y237
L
G
Q
D
K
V
S
Y
E
V
P
R
L
H
G
Site 16
S275
H
V
T
L
L
D
D
S
N
E
D
F
S
A
S
Site 17
S280
D
D
S
N
E
D
F
S
A
S
P
I
F
T
D
Site 18
S282
S
N
E
D
F
S
A
S
P
I
F
T
D
T
V
Site 19
Y309
T
L
P
P
L
E
V
Y
V
C
R
V
R
N
N
Site 20
T335
R
K
A
G
C
K
L
T
I
C
P
Q
A
E
N
Site 21
Y356
Q
D
E
M
E
L
G
Y
V
Q
A
P
H
K
T
Site 22
T363
Y
V
Q
A
P
H
K
T
L
P
V
V
F
D
S
Site 23
S370
T
L
P
V
V
F
D
S
P
R
N
G
E
L
Q
Site 24
Y381
G
E
L
Q
D
F
P
Y
K
R
I
L
G
P
D
Site 25
Y391
I
L
G
P
D
F
G
Y
V
T
R
E
P
R
D
Site 26
T393
G
P
D
F
G
Y
V
T
R
E
P
R
D
R
S
Site 27
S400
T
R
E
P
R
D
R
S
V
S
G
L
D
S
F
Site 28
S402
E
P
R
D
R
S
V
S
G
L
D
S
F
G
N
Site 29
S406
R
S
V
S
G
L
D
S
F
G
N
L
E
V
S
Site 30
S437
I
G
G
N
L
P
G
S
S
G
R
R
V
T
Q
Site 31
S438
G
G
N
L
P
G
S
S
G
R
R
V
T
Q
V
Site 32
T443
G
S
S
G
R
R
V
T
Q
V
V
R
D
F
L
Site 33
S476
G
H
V
D
E
F
L
S
F
V
P
A
P
D
G
Site 34
T525
V
D
D
E
Q
V
K
T
I
S
I
N
Q
V
L
Site 35
S527
D
E
Q
V
K
T
I
S
I
N
Q
V
L
S
N
Site 36
S533
I
S
I
N
Q
V
L
S
N
K
D
L
I
N
Y
Site 37
Y540
S
N
K
D
L
I
N
Y
N
K
F
V
Q
S
C
Site 38
T575
D
I
P
Q
L
F
K
T
E
R
K
K
A
T
A
Site 39
Y637
F
I
D
D
F
T
P
Y
H
M
L
H
G
E
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation