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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HAP95
Full Name:
A-kinase anchor protein 8-like
Alias:
A kinase (PRKA) anchor protein 8-like; AKAP8L; A-kinase anchor protein-like protein 8; AKP8L; AP8L; HA95; Helicase A-binding protein 95; Homologous to AKAP95 protein; HRIHFB2018; NAKAP95; Neighbor of A kinase anchoring protein 95; Neighbor of A-kinase anchoring protein 95; Neighbor of A-kinase-anchoring protein 95
Type:
Adapter/scaffold protein
Mass (Da):
71640
Number AA:
646
UniProt ID:
Q9ULX6
International Prot ID:
IPI00297455
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005694
GO:0005737
GO:0016363
Uniprot
OncoNet
Molecular Function:
GO:0017151
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
G
F
V
Q
G
S
E
T
T
L
Q
S
T
Y
S
Site 2
S16
G
S
E
T
T
L
Q
S
T
Y
S
D
T
S
A
Site 3
T17
S
E
T
T
L
Q
S
T
Y
S
D
T
S
A
Q
Site 4
S19
T
T
L
Q
S
T
Y
S
D
T
S
A
Q
P
T
Site 5
S22
Q
S
T
Y
S
D
T
S
A
Q
P
T
C
D
Y
Site 6
T26
S
D
T
S
A
Q
P
T
C
D
Y
G
Y
G
T
Site 7
Y29
S
A
Q
P
T
C
D
Y
G
Y
G
T
W
N
S
Site 8
Y31
Q
P
T
C
D
Y
G
Y
G
T
W
N
S
G
T
Site 9
Y42
N
S
G
T
N
R
G
Y
E
G
Y
G
Y
G
Y
Site 10
Y45
T
N
R
G
Y
E
G
Y
G
Y
G
Y
G
Y
G
Site 11
Y47
R
G
Y
E
G
Y
G
Y
G
Y
G
Y
G
Q
D
Site 12
Y51
G
Y
G
Y
G
Y
G
Y
G
Q
D
N
T
T
N
Site 13
Y59
G
Q
D
N
T
T
N
Y
G
Y
G
M
A
T
S
Site 14
Y61
D
N
T
T
N
Y
G
Y
G
M
A
T
S
H
S
Site 15
S68
Y
G
M
A
T
S
H
S
W
E
M
P
S
S
D
Site 16
S74
H
S
W
E
M
P
S
S
D
T
N
A
N
T
S
Site 17
T80
S
S
D
T
N
A
N
T
S
A
S
G
S
A
S
Site 18
S81
S
D
T
N
A
N
T
S
A
S
G
S
A
S
A
Site 19
S83
T
N
A
N
T
S
A
S
G
S
A
S
A
D
S
Site 20
S85
A
N
T
S
A
S
G
S
A
S
A
D
S
V
L
Site 21
S87
T
S
A
S
G
S
A
S
A
D
S
V
L
S
R
Site 22
S90
S
G
S
A
S
A
D
S
V
L
S
R
I
N
Q
Site 23
Y115
D
M
M
Q
G
G
V
Y
G
S
G
G
E
R
Y
Site 24
Y122
Y
G
S
G
G
E
R
Y
D
S
Y
E
S
C
D
Site 25
S124
S
G
G
E
R
Y
D
S
Y
E
S
C
D
S
R
Site 26
Y125
G
G
E
R
Y
D
S
Y
E
S
C
D
S
R
A
Site 27
S127
E
R
Y
D
S
Y
E
S
C
D
S
R
A
V
L
Site 28
S130
D
S
Y
E
S
C
D
S
R
A
V
L
S
E
R
Site 29
S135
C
D
S
R
A
V
L
S
E
R
D
L
Y
R
S
Site 30
Y140
V
L
S
E
R
D
L
Y
R
S
G
Y
D
Y
S
Site 31
S142
S
E
R
D
L
Y
R
S
G
Y
D
Y
S
E
L
Site 32
Y144
R
D
L
Y
R
S
G
Y
D
Y
S
E
L
D
P
Site 33
Y146
L
Y
R
S
G
Y
D
Y
S
E
L
D
P
E
M
Site 34
S147
Y
R
S
G
Y
D
Y
S
E
L
D
P
E
M
E
Site 35
Y161
E
M
A
Y
E
G
Q
Y
D
A
Y
R
D
Q
F
Site 36
Y164
Y
E
G
Q
Y
D
A
Y
R
D
Q
F
R
M
R
Site 37
T175
F
R
M
R
G
N
D
T
F
G
P
R
A
Q
G
Site 38
S189
G
W
A
R
D
A
R
S
G
R
P
M
A
S
G
Site 39
Y197
G
R
P
M
A
S
G
Y
G
R
M
W
E
D
P
Site 40
S213
G
A
R
G
Q
C
M
S
G
A
S
R
L
P
S
Site 41
S216
G
Q
C
M
S
G
A
S
R
L
P
S
L
F
S
Site 42
S223
S
R
L
P
S
L
F
S
Q
N
I
I
P
E
Y
Site 43
Y230
S
Q
N
I
I
P
E
Y
G
M
F
Q
G
M
R
Site 44
T268
R
T
W
K
T
W
T
T
A
D
F
R
T
K
K
Site 45
S283
K
K
R
K
Q
G
G
S
P
D
E
P
D
S
K
Site 46
S289
G
S
P
D
E
P
D
S
K
A
T
R
T
D
C
Site 47
T292
D
E
P
D
S
K
A
T
R
T
D
C
S
D
N
Site 48
T294
P
D
S
K
A
T
R
T
D
C
S
D
N
S
D
Site 49
S297
K
A
T
R
T
D
C
S
D
N
S
D
S
D
N
Site 50
S300
R
T
D
C
S
D
N
S
D
S
D
N
D
E
G
Site 51
S302
D
C
S
D
N
S
D
S
D
N
D
E
G
T
E
Site 52
T308
D
S
D
N
D
E
G
T
E
G
E
A
T
E
G
Site 53
T313
E
G
T
E
G
E
A
T
E
G
L
E
G
T
E
Site 54
T361
T
Q
D
E
N
G
Q
T
K
R
K
L
Q
A
G
Site 55
S371
K
L
Q
A
G
K
K
S
Q
D
K
Q
K
K
R
Site 56
Y396
F
V
C
S
L
C
K
Y
R
T
F
Y
E
D
E
Site 57
Y400
L
C
K
Y
R
T
F
Y
E
D
E
M
A
S
H
Site 58
S410
E
M
A
S
H
L
D
S
K
F
H
K
E
H
F
Site 59
Y419
F
H
K
E
H
F
K
Y
V
G
T
K
L
P
K
Site 60
Y435
T
A
D
F
L
Q
E
Y
V
T
N
K
T
K
K
Site 61
T449
K
T
E
E
L
R
K
T
V
E
D
L
D
G
L
Site 62
Y461
D
G
L
I
Q
Q
I
Y
R
D
Q
D
L
T
Q
Site 63
T467
I
Y
R
D
Q
D
L
T
Q
E
I
A
M
E
H
Site 64
T504
I
I
Q
K
H
L
K
T
M
D
H
N
R
N
R
Site 65
S518
R
R
L
M
M
E
Q
S
K
K
S
S
L
M
V
Site 66
S522
M
E
Q
S
K
K
S
S
L
M
V
A
R
S
I
Site 67
Y542
I
S
K
K
L
E
R
Y
L
K
G
E
N
P
F
Site 68
T550
L
K
G
E
N
P
F
T
D
S
P
E
E
E
K
Site 69
S552
G
E
N
P
F
T
D
S
P
E
E
E
K
E
Q
Site 70
S579
Q
G
E
A
A
G
I
S
E
G
A
E
G
V
P
Site 71
S601
E
P
A
P
G
A
V
S
P
P
P
P
P
P
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation