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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
STAP1
Full Name:
Signal-transducing adaptor protein 1
Alias:
BCR downstream signaling 1; BCR downstream signaling protein 1; BRDG1; Signal transducing adaptor family member 1; STAP-1; Stem cell adaptor protein 1
Type:
Adaptor/scaffold
Mass (Da):
34291
Number AA:
295
UniProt ID:
Q9ULZ2
International Prot ID:
IPI00015876
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006886
GO:0006944
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T22
F
Q
E
R
L
K
I
T
A
L
P
L
Y
F
E
Site 2
Y27
K
I
T
A
L
P
L
Y
F
E
G
F
L
L
I
Site 3
S37
G
F
L
L
I
K
R
S
G
Y
R
E
Y
E
H
Site 4
Y39
L
L
I
K
R
S
G
Y
R
E
Y
E
H
Y
W
Site 5
Y42
K
R
S
G
Y
R
E
Y
E
H
Y
W
T
E
L
Site 6
Y45
G
Y
R
E
Y
E
H
Y
W
T
E
L
R
G
T
Site 7
T47
R
E
Y
E
H
Y
W
T
E
L
R
G
T
T
L
Site 8
T53
W
T
E
L
R
G
T
T
L
F
F
Y
T
D
K
Site 9
Y57
R
G
T
T
L
F
F
Y
T
D
K
K
S
I
I
Site 10
T58
G
T
T
L
F
F
Y
T
D
K
K
S
I
I
Y
Site 11
Y65
T
D
K
K
S
I
I
Y
V
D
K
L
D
I
V
Site 12
T75
K
L
D
I
V
D
L
T
C
L
T
E
Q
N
S
Site 13
T78
I
V
D
L
T
C
L
T
E
Q
N
S
T
E
K
Site 14
S82
T
C
L
T
E
Q
N
S
T
E
K
N
C
A
K
Site 15
T106
V
Q
L
K
T
E
N
T
E
S
G
E
E
W
R
Site 16
S108
L
K
T
E
N
T
E
S
G
E
E
W
R
G
F
Site 17
T152
E
K
K
R
R
I
E
T
E
Q
S
T
S
V
E
Site 18
S155
R
R
I
E
T
E
Q
S
T
S
V
E
K
E
K
Site 19
S157
I
E
T
E
Q
S
T
S
V
E
K
E
K
E
P
Site 20
T165
V
E
K
E
K
E
P
T
E
D
Y
V
D
V
L
Site 21
Y168
E
K
E
P
T
E
D
Y
V
D
V
L
N
P
M
Site 22
T181
P
M
P
A
C
F
Y
T
V
S
R
K
E
A
T
Site 23
S183
P
A
C
F
Y
T
V
S
R
K
E
A
T
E
M
Site 24
S196
E
M
L
Q
K
N
P
S
L
G
N
M
I
L
R
Site 25
S206
N
M
I
L
R
P
G
S
D
S
R
N
Y
S
I
Site 26
S208
I
L
R
P
G
S
D
S
R
N
Y
S
I
T
I
Site 27
Y211
P
G
S
D
S
R
N
Y
S
I
T
I
R
Q
E
Site 28
S212
G
S
D
S
R
N
Y
S
I
T
I
R
Q
E
I
Site 29
T214
D
S
R
N
Y
S
I
T
I
R
Q
E
I
D
I
Site 30
Y227
D
I
P
R
I
K
H
Y
K
V
M
S
V
G
Q
Site 31
Y255
N
L
F
S
V
I
D
Y
F
V
K
E
T
R
G
Site 32
S270
N
L
R
P
F
I
C
S
T
D
E
N
T
G
Q
Site 33
S280
E
N
T
G
Q
E
P
S
M
E
G
R
S
E
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation