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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
APC10
Full Name:
Anaphase-promoting complex subunit 10
Alias:
ANAPC10; Anaphase promoting complex 10; Anaphase promoting complex subunit 10; Anaphase-promoting complex 10; Cyclosome 10; DKFZP564L0562; DOC1
Type:
Ubiquitin conjugating system
Mass (Da):
21250
Number AA:
185
UniProt ID:
Q9UM13
International Prot ID:
IPI00007088
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005680
GO:0005829
GO:0005654
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004842
PhosphoSite+
KinaseNET
Biological Process:
GO:0000086
GO:0031145
GO:0051301
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T3
_
_
_
_
_
M
T
T
P
N
K
T
P
P
G
Site 2
T7
_
M
T
T
P
N
K
T
P
P
G
A
D
P
K
Site 3
T21
K
Q
L
E
R
T
G
T
V
R
E
I
G
S
Q
Site 4
S27
G
T
V
R
E
I
G
S
Q
A
V
W
S
L
S
Site 5
S32
I
G
S
Q
A
V
W
S
L
S
S
C
K
P
G
Site 6
S34
S
Q
A
V
W
S
L
S
S
C
K
P
G
F
G
Site 7
T52
L
R
D
D
N
L
E
T
Y
W
Q
S
D
G
S
Site 8
Y53
R
D
D
N
L
E
T
Y
W
Q
S
D
G
S
Q
Site 9
T72
N
I
Q
F
R
R
K
T
T
V
K
T
L
C
I
Site 10
T73
I
Q
F
R
R
K
T
T
V
K
T
L
C
I
Y
Site 11
T76
R
R
K
T
T
V
K
T
L
C
I
Y
A
D
Y
Site 12
Y80
T
V
K
T
L
C
I
Y
A
D
Y
K
S
D
E
Site 13
Y83
T
L
C
I
Y
A
D
Y
K
S
D
E
S
Y
T
Site 14
S85
C
I
Y
A
D
Y
K
S
D
E
S
Y
T
P
S
Site 15
S88
A
D
Y
K
S
D
E
S
Y
T
P
S
K
I
S
Site 16
Y89
D
Y
K
S
D
E
S
Y
T
P
S
K
I
S
V
Site 17
T90
Y
K
S
D
E
S
Y
T
P
S
K
I
S
V
R
Site 18
S92
S
D
E
S
Y
T
P
S
K
I
S
V
R
V
G
Site 19
S95
S
Y
T
P
S
K
I
S
V
R
V
G
N
N
F
Site 20
T125
G
W
I
H
V
P
L
T
D
N
H
K
K
P
T
Site 21
T134
N
H
K
K
P
T
R
T
F
M
I
Q
I
A
V
Site 22
Y159
H
M
R
Q
I
K
I
Y
T
P
V
E
E
S
S
Site 23
T160
M
R
Q
I
K
I
Y
T
P
V
E
E
S
S
I
Site 24
S166
Y
T
P
V
E
E
S
S
I
G
K
F
P
R
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation