PhosphoNET

           
Protein Info 
   
Short Name:  NDRG2
Full Name:  Protein NDRG2
Alias:  KIAA1248; NDR2; NDRG family member 2; NDRG2 protein; Protein Syld709613; SYLD; Syld709613 protein
Type:  Tumor suppressor; Apoptosis
Mass (Da):  40798
Number AA:  371
UniProt ID:  Q9UN36
International Prot ID:  IPI00008994
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005794  GO:0005813  GO:0005829 Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:  GO:0030154  GO:0007399   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T10ELQEVQITEEKPLLP
Site 2T20KPLLPGQTPEAAKEA
Site 3S42LDQGQTHSVETPYGS
Site 4T45GQTHSVETPYGSVTF
Site 5Y47THSVETPYGSVTFTV
Site 6S49SVETPYGSVTFTVYG
Site 7T51ETPYGSVTFTVYGTP
Site 8T53PYGSVTFTVYGTPKP
Site 9Y55GSVTFTVYGTPKPKR
Site 10T57VTFTVYGTPKPKRPA
Site 11T67PKRPAILTYHDVGLN
Site 12Y68KRPAILTYHDVGLNY
Site 13Y75YHDVGLNYKSCFQPL
Site 14Y116APVFPLGYQYPSLDQ
Site 15S120PLGYQYPSLDQLADM
Site 16S203MILGHLFSQEELSGN
Site 17S208LFSQEELSGNSELIQ
Site 18Y217NSELIQKYRNIITHA
Site 19Y233NLDNIELYWNSYNNR
Site 20Y237IELYWNSYNNRRDLN
Site 21T281CNSKLDPTQTSFLKM
Site 22T283SKLDPTQTSFLKMAD
Site 23S284KLDPTQTSFLKMADS
Site 24S291SFLKMADSGGQPQLT
Site 25T298SGGQPQLTQPGKLTE
Site 26Y309KLTEAFKYFLQGMGY
Site 27S319QGMGYMASSCMTRLS
Site 28S320GMGYMASSCMTRLSR
Site 29T323YMASSCMTRLSRSRT
Site 30S326SSCMTRLSRSRTASL
Site 31S328CMTRLSRSRTASLTS
Site 32T330TRLSRSRTASLTSAA
Site 33S332 LSRSRTASLTSAASV
Site 34T334RSRTASLTSAASVDG
Site 35S335SRTASLTSAASVDGN
Site 36S338ASLTSAASVDGNRSR
Site 37S344ASVDGNRSRSRTLSQ
Site 38S346VDGNRSRSRTLSQSS
Site 39T348 GNRSRSRTLSQSSES
Site 40S350RSRSRTLSQSSESGT
Site 41S352RSRTLSQSSESGTLS
Site 42S353SRTLSQSSESGTLSS
Site 43S355TLSQSSESGTLSSGP
Site 44T357SQSSESGTLSSGPPG
Site 45S359SSESGTLSSGPPGHT
Site 46S360SESGTLSSGPPGHTM
Site 47T366SSGPPGHTMEVSC__
Site 48S370PGHTMEVSC______
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation