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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NPIP
Full Name:
Alias:
Type:
Mass (Da):
40133
Number AA:
350
UniProt ID:
Q9UND3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T34
A
D
H
R
H
R
G
T
D
F
G
G
S
P
W
Site 2
T60
K
F
A
I
S
L
C
T
S
Y
L
C
V
S
F
Site 3
S61
F
A
I
S
L
C
T
S
Y
L
C
V
S
F
L
Site 4
T70
L
C
V
S
F
L
K
T
I
F
P
S
Q
N
G
Site 5
S74
F
L
K
T
I
F
P
S
Q
N
G
H
D
G
S
Site 6
S81
S
Q
N
G
H
D
G
S
T
D
V
Q
Q
R
A
Site 7
T82
Q
N
G
H
D
G
S
T
D
V
Q
Q
R
A
R
Site 8
S91
V
Q
Q
R
A
R
R
S
N
R
R
R
Q
E
G
Site 9
T108
I
V
L
E
D
I
F
T
L
W
R
Q
V
E
T
Site 10
T115
T
L
W
R
Q
V
E
T
K
V
R
A
K
I
R
Site 11
T127
K
I
R
K
M
K
V
T
T
K
V
N
R
H
D
Site 12
T142
K
I
N
G
K
R
K
T
A
K
E
H
L
R
K
Site 13
S151
K
E
H
L
R
K
L
S
M
K
E
R
E
H
G
Site 14
S165
G
E
K
E
R
Q
V
S
E
A
E
E
N
G
K
Site 15
Y181
D
M
K
E
I
H
T
Y
M
E
M
F
Q
R
A
Site 16
Y198
L
R
R
R
A
E
D
Y
Y
R
C
K
I
T
P
Site 17
Y199
R
R
R
A
E
D
Y
Y
R
C
K
I
T
P
S
Site 18
T204
D
Y
Y
R
C
K
I
T
P
S
A
R
K
P
L
Site 19
S225
A
A
V
E
H
R
H
S
S
G
L
P
Y
W
P
Site 20
S226
A
V
E
H
R
H
S
S
G
L
P
Y
W
P
Y
Site 21
Y230
R
H
S
S
G
L
P
Y
W
P
Y
L
T
A
E
Site 22
Y233
S
G
L
P
Y
W
P
Y
L
T
A
E
T
L
K
Site 23
T251
G
H
Q
P
P
P
P
T
Q
Q
H
S
I
I
D
Site 24
S255
P
P
P
T
Q
Q
H
S
I
I
D
N
S
L
S
Site 25
S260
Q
H
S
I
I
D
N
S
L
S
L
K
T
P
S
Site 26
S262
S
I
I
D
N
S
L
S
L
K
T
P
S
E
C
Site 27
T265
D
N
S
L
S
L
K
T
P
S
E
C
L
L
T
Site 28
S281
L
P
P
S
A
L
P
S
A
D
D
N
L
K
T
Site 29
T288
S
A
D
D
N
L
K
T
P
A
E
C
L
L
Y
Site 30
Y295
T
P
A
E
C
L
L
Y
P
L
P
P
S
A
D
Site 31
S300
L
L
Y
P
L
P
P
S
A
D
D
N
L
K
T
Site 32
T307
S
A
D
D
N
L
K
T
P
P
E
C
L
L
T
Site 33
T314
T
P
P
E
C
L
L
T
P
L
P
P
S
A
P
Site 34
S319
L
L
T
P
L
P
P
S
A
P
P
S
V
D
D
Site 35
S323
L
P
P
S
A
P
P
S
V
D
D
N
L
K
T
Site 36
T330
S
V
D
D
N
L
K
T
P
P
E
C
V
C
S
Site 37
S337
T
P
P
E
C
V
C
S
L
P
F
H
P
Q
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation