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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WDR3
Full Name:
WD REPEAT-CONTAINING PROTEIN 3.
Alias:
FLJ12796; WD repeat domain 3; WDR3 protein; WD-repeat protein 3
Type:
Uncharacterized protein
Mass (Da):
106099
Number AA:
943
UniProt ID:
Q9UNX4
International Prot ID:
IPI00009471
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0030529
GO:0030684
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006364
GO:0006396
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y7
_
M
G
L
T
K
Q
Y
L
R
Y
V
A
S
A
Site 2
Y10
L
T
K
Q
Y
L
R
Y
V
A
S
A
V
F
G
Site 3
S13
Q
Y
L
R
Y
V
A
S
A
V
F
G
V
I
G
Site 4
T30
K
G
N
I
V
F
V
T
L
R
G
E
K
G
R
Site 5
Y38
L
R
G
E
K
G
R
Y
V
A
V
P
A
C
E
Site 6
T69
Q
G
L
K
Q
E
V
T
C
L
C
P
S
P
D
Site 7
S93
D
G
S
I
R
I
F
S
L
L
S
G
E
G
N
Site 8
S96
I
R
I
F
S
L
L
S
G
E
G
N
V
T
F
Site 9
T102
L
S
G
E
G
N
V
T
F
N
G
H
K
A
A
Site 10
S124
Q
L
G
G
R
L
A
S
G
S
K
D
T
D
I
Site 11
S126
G
G
R
L
A
S
G
S
K
D
T
D
I
I
V
Site 12
Y143
V
I
N
E
S
G
L
Y
R
L
K
G
H
K
D
Site 13
T153
K
G
H
K
D
A
I
T
Q
A
L
F
L
R
E
Site 14
T171
L
V
T
S
G
K
D
T
M
V
K
W
W
D
L
Site 15
T208
S
E
E
K
R
L
I
T
G
A
S
D
S
E
L
Site 16
S211
K
R
L
I
T
G
A
S
D
S
E
L
R
V
W
Site 17
Y222
L
R
V
W
D
I
A
Y
L
Q
E
I
E
D
P
Site 18
S240
D
P
K
K
I
K
G
S
S
P
G
I
Q
D
T
Site 19
S241
P
K
K
I
K
G
S
S
P
G
I
Q
D
T
L
Site 20
T247
S
S
P
G
I
Q
D
T
L
E
A
E
D
G
A
Site 21
T257
A
E
D
G
A
F
E
T
D
E
A
P
E
D
R
Site 22
S267
A
P
E
D
R
I
L
S
C
R
K
A
G
S
I
Site 23
S273
L
S
C
R
K
A
G
S
I
M
R
E
G
R
D
Site 24
S310
L
E
L
F
C
I
L
S
K
K
E
I
Q
K
K
Site 25
S333
R
K
K
A
K
L
H
S
S
K
G
E
E
E
D
Site 26
T357
Q
D
E
I
Q
R
V
T
N
I
K
T
S
A
K
Site 27
S367
K
T
S
A
K
I
K
S
F
D
L
I
H
S
P
Site 28
S373
K
S
F
D
L
I
H
S
P
H
G
E
L
K
A
Site 29
S393
N
N
L
V
E
L
Y
S
L
N
P
S
L
P
T
Site 30
S397
E
L
Y
S
L
N
P
S
L
P
T
P
Q
P
V
Site 31
T400
S
L
N
P
S
L
P
T
P
Q
P
V
R
T
S
Site 32
T406
P
T
P
Q
P
V
R
T
S
R
I
T
I
G
G
Site 33
S407
T
P
Q
P
V
R
T
S
R
I
T
I
G
G
H
Site 34
T410
P
V
R
T
S
R
I
T
I
G
G
H
R
S
D
Site 35
S416
I
T
I
G
G
H
R
S
D
V
R
T
L
S
F
Site 36
T420
G
H
R
S
D
V
R
T
L
S
F
S
S
D
N
Site 37
S422
R
S
D
V
R
T
L
S
F
S
S
D
N
I
A
Site 38
Y456
I
R
T
M
T
C
E
Y
A
L
C
S
F
F
V
Site 39
T475
Q
V
V
I
G
T
K
T
G
K
L
Q
L
Y
D
Site 40
Y481
K
T
G
K
L
Q
L
Y
D
L
A
S
G
N
L
Site 41
S501
A
H
D
G
A
L
W
S
M
S
L
S
P
D
Q
Site 42
S503
D
G
A
L
W
S
M
S
L
S
P
D
Q
R
G
Site 43
S505
A
L
W
S
M
S
L
S
P
D
Q
R
G
F
V
Site 44
S519
V
T
G
G
A
D
K
S
V
K
F
W
D
F
E
Site 45
S533
E
L
V
K
D
E
N
S
T
Q
K
R
L
S
V
Site 46
S539
N
S
T
Q
K
R
L
S
V
K
Q
T
R
T
L
Site 47
T543
K
R
L
S
V
K
Q
T
R
T
L
Q
L
D
E
Site 48
T572
A
V
S
L
L
D
C
T
V
K
I
F
Y
V
D
Site 49
T580
V
K
I
F
Y
V
D
T
L
K
F
F
L
S
L
Site 50
S586
D
T
L
K
F
F
L
S
L
Y
G
H
K
L
P
Site 51
Y588
L
K
F
F
L
S
L
Y
G
H
K
L
P
V
I
Site 52
Y638
A
H
D
D
S
V
M
Y
L
Q
F
V
P
K
S
Site 53
T670
D
K
F
E
H
I
Q
T
L
E
G
H
H
Q
E
Site 54
Y689
A
V
S
P
S
G
D
Y
V
V
S
S
S
H
D
Site 55
S692
P
S
G
D
Y
V
V
S
S
S
H
D
K
S
L
Site 56
S693
S
G
D
Y
V
V
S
S
S
H
D
K
S
L
R
Site 57
S694
G
D
Y
V
V
S
S
S
H
D
K
S
L
R
L
Site 58
S698
V
S
S
S
H
D
K
S
L
R
L
W
E
R
T
Site 59
T705
S
L
R
L
W
E
R
T
R
E
P
L
I
L
E
Site 60
Y723
E
M
E
R
E
A
E
Y
E
E
S
V
A
K
E
Site 61
S726
R
E
A
E
Y
E
E
S
V
A
K
E
D
Q
P
Site 62
S743
P
G
E
T
Q
G
D
S
Y
F
T
G
K
K
T
Site 63
Y744
G
E
T
Q
G
D
S
Y
F
T
G
K
K
T
I
Site 64
T753
T
G
K
K
T
I
E
T
V
K
A
A
E
R
I
Site 65
T771
I
E
L
Y
R
E
E
T
A
K
M
K
E
H
K
Site 66
S817
E
I
F
K
G
I
K
S
S
E
L
E
E
S
L
Site 67
S818
I
F
K
G
I
K
S
S
E
L
E
E
S
L
L
Site 68
S823
K
S
S
E
L
E
E
S
L
L
V
L
P
F
S
Site 69
T883
V
I
E
K
L
R
E
T
T
I
S
K
V
S
Q
Site 70
T884
I
E
K
L
R
E
T
T
I
S
K
V
S
Q
V
Site 71
S886
K
L
R
E
T
T
I
S
K
V
S
Q
V
R
D
Site 72
S889
E
T
T
I
S
K
V
S
Q
V
R
D
V
I
G
Site 73
Y904
F
N
M
A
G
L
D
Y
L
K
R
E
C
E
A
Site 74
S913
K
R
E
C
E
A
K
S
E
V
M
F
F
A
D
Site 75
T941
K
R
E
K
L
I
L
T
L
T
_
_
_
_
_
Site 76
T943
E
K
L
I
L
T
L
T
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation