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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KCNJ14
Full Name:
Alias:
Inward rectifier K(+) channel Kir2.4;Potassium channel, inwardly rectifying subfamily J member 14
Type:
Mass (Da):
47846
Number AA:
436
UniProt ID:
Q9UNX9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
A
R
A
L
R
R
L
S
G
A
L
D
S
G
D
Site 2
S16
R
L
S
G
A
L
D
S
G
D
S
R
A
G
D
Site 3
S19
G
A
L
D
S
G
D
S
R
A
G
D
E
E
E
Site 4
S43
W
A
P
A
P
V
Q
S
P
V
G
R
R
R
G
Site 5
Y73
L
G
G
Q
G
A
R
Y
L
S
D
L
F
T
T
Site 6
S147
F
A
L
E
T
Q
T
S
I
G
Y
G
V
R
S
Site 7
S154
S
I
G
Y
G
V
R
S
V
T
E
E
C
P
A
Site 8
T197
K
P
K
K
R
N
E
T
L
V
F
S
E
N
A
Site 9
S225
R
V
G
N
L
R
R
S
H
L
V
E
A
H
V
Site 10
T242
Q
L
L
Q
P
R
V
T
P
E
G
E
Y
I
P
Site 11
S282
V
H
E
I
D
S
A
S
P
L
Y
E
L
G
R
Site 12
Y285
I
D
S
A
S
P
L
Y
E
L
G
R
A
E
L
Site 13
T314
V
E
A
T
A
M
T
T
Q
C
R
S
S
Y
L
Site 14
S319
M
T
T
Q
C
R
S
S
Y
L
P
G
E
L
L
Site 15
Y320
T
T
Q
C
R
S
S
Y
L
P
G
E
L
L
W
Site 16
S340
P
V
L
F
Q
R
G
S
Q
Y
E
V
D
Y
R
Site 17
Y342
L
F
Q
R
G
S
Q
Y
E
V
D
Y
R
H
F
Site 18
Y346
G
S
Q
Y
E
V
D
Y
R
H
F
H
R
T
Y
Site 19
T352
D
Y
R
H
F
H
R
T
Y
E
V
P
G
T
P
Site 20
Y353
Y
R
H
F
H
R
T
Y
E
V
P
G
T
P
V
Site 21
T358
R
T
Y
E
V
P
G
T
P
V
C
S
A
K
E
Site 22
S374
D
E
R
A
E
Q
A
S
H
S
L
K
S
S
F
Site 23
S376
R
A
E
Q
A
S
H
S
L
K
S
S
F
P
G
Site 24
S379
Q
A
S
H
S
L
K
S
S
F
P
G
S
L
T
Site 25
S380
A
S
H
S
L
K
S
S
F
P
G
S
L
T
A
Site 26
T386
S
S
F
P
G
S
L
T
A
F
C
Y
E
N
E
Site 27
S397
Y
E
N
E
L
A
L
S
C
C
Q
E
E
D
E
Site 28
T408
E
E
D
E
D
D
E
T
E
E
G
N
G
V
E
Site 29
S422
E
T
E
D
G
A
A
S
P
R
V
L
T
P
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation