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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FZD1
Full Name:
Frizzled-1 precursor
Alias:
DKFZp564G072; frizzled 1; frizzled, of, 1; frizzled-1; Fz-1; FzE1; Wnt receptor
Type:
Mass (Da):
71160
Number AA:
UniProt ID:
Q9UP38
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0004930
GO:0004926
PhosphoSite+
KinaseNET
Biological Process:
GO:0007186
GO:0016055
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
E
E
E
A
P
K
K
S
R
A
A
G
G
G
A
Site 2
S35
A
R
L
A
E
E
G
S
G
D
A
G
G
R
R
Site 3
Y102
Q
Q
Q
S
G
Q
Q
Y
N
G
E
R
G
I
S
Site 4
Y115
I
S
V
P
D
H
G
Y
C
Q
P
I
S
I
P
Site 5
Y129
P
L
C
T
D
I
A
Y
N
Q
T
I
M
P
N
Site 6
S189
Q
A
L
P
P
C
R
S
L
C
E
R
A
R
Q
Site 7
S233
L
C
V
G
Q
N
T
S
D
K
G
T
P
T
P
Site 8
T237
Q
N
T
S
D
K
G
T
P
T
P
S
L
L
P
Site 9
T239
T
S
D
K
G
T
P
T
P
S
L
L
P
E
F
Site 10
S241
D
K
G
T
P
T
P
S
L
L
P
E
F
W
T
Site 11
T248
S
L
L
P
E
F
W
T
S
N
P
Q
H
G
G
Site 12
S249
L
L
P
E
F
W
T
S
N
P
Q
H
G
G
G
Site 13
S269
F
P
G
G
A
G
A
S
E
R
G
K
F
S
C
Site 14
S275
A
S
E
R
G
K
F
S
C
P
R
A
L
K
V
Site 15
Y285
R
A
L
K
V
P
S
Y
L
N
Y
H
F
L
G
Site 16
Y288
K
V
P
S
Y
L
N
Y
H
F
L
G
E
K
D
Site 17
Y310
T
K
V
Y
G
L
M
Y
F
G
P
E
E
L
R
Site 18
T321
E
E
L
R
F
S
R
T
W
I
G
I
W
S
V
Site 19
S349
L
V
D
M
R
R
F
S
Y
P
E
R
P
I
I
Site 20
Y350
V
D
M
R
R
F
S
Y
P
E
R
P
I
I
F
Site 21
T392
F
A
E
D
G
A
R
T
V
A
Q
G
T
K
K
Site 22
S444
H
E
A
I
E
A
N
S
Q
Y
F
H
L
A
A
Site 23
T518
V
S
L
F
R
I
R
T
I
M
K
H
D
G
T
Site 24
T525
T
I
M
K
H
D
G
T
K
T
E
K
L
E
K
Site 25
S541
M
V
R
I
G
V
F
S
V
L
Y
T
V
P
A
Site 26
S597
A
P
P
H
P
P
M
S
P
D
F
T
V
F
M
Site 27
Y607
F
T
V
F
M
I
K
Y
L
M
T
L
I
V
G
Site 28
S617
T
L
I
V
G
I
T
S
G
F
W
I
W
S
G
Site 29
Y634
L
N
S
W
R
K
F
Y
T
R
L
T
N
S
K
Site 30
T638
R
K
F
Y
T
R
L
T
N
S
K
Q
G
E
T
Site 31
S640
F
Y
T
R
L
T
N
S
K
Q
G
E
T
T
V
Site 32
T646
N
S
K
Q
G
E
T
T
V
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation