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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PLAGL2
Full Name:
Alias:
Pleiomorphic adenoma-like protein 2
Type:
Mass (Da):
54584
Number AA:
496
UniProt ID:
Q9UPG8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S36
P
R
G
R
E
A
E
S
Q
V
K
C
Q
C
E
Site 2
T47
C
Q
C
E
I
S
G
T
P
F
S
N
G
E
K
Site 3
S50
E
I
S
G
T
P
F
S
N
G
E
K
L
R
P
Site 4
S59
G
E
K
L
R
P
H
S
L
P
Q
P
E
Q
R
Site 5
Y68
P
Q
P
E
Q
R
P
Y
S
C
P
Q
L
H
C
Site 6
S69
Q
P
E
Q
R
P
Y
S
C
P
Q
L
H
C
G
Site 7
Y83
G
K
A
F
A
S
K
Y
K
L
Y
R
H
M
A
Site 8
Y86
F
A
S
K
Y
K
L
Y
R
H
M
A
T
H
S
Site 9
T119
H
L
R
N
H
L
Q
T
H
D
P
N
K
E
A
Site 10
Y136
C
S
E
C
G
K
N
Y
N
T
K
L
G
Y
R
Site 11
S152
H
L
A
M
H
A
A
S
S
G
D
L
S
C
K
Site 12
S179
L
E
H
L
K
A
H
S
R
R
V
A
G
G
A
Site 13
Y201
D
H
C
D
R
R
F
Y
T
R
K
D
V
R
R
Site 14
Y223
R
K
D
F
L
C
Q
Y
C
A
Q
R
F
G
R
Site 15
T235
F
G
R
K
D
H
L
T
R
H
V
K
K
S
H
Site 16
S241
L
T
R
H
V
K
K
S
H
S
Q
E
L
L
K
Site 17
S243
R
H
V
K
K
S
H
S
Q
E
L
L
K
I
K
Site 18
T251
Q
E
L
L
K
I
K
T
E
P
V
D
M
L
G
Site 19
T265
G
L
L
S
C
S
S
T
V
S
V
K
E
E
L
Site 20
S267
L
S
C
S
S
T
V
S
V
K
E
E
L
S
P
Site 21
S307
A
H
I
P
T
M
P
S
T
G
V
P
H
S
L
Site 22
S313
P
S
T
G
V
P
H
S
L
V
H
N
T
L
P
Site 23
T318
P
H
S
L
V
H
N
T
L
P
M
G
M
S
Y
Site 24
S324
N
T
L
P
M
G
M
S
Y
P
L
E
S
S
P
Site 25
Y325
T
L
P
M
G
M
S
Y
P
L
E
S
S
P
I
Site 26
S329
G
M
S
Y
P
L
E
S
S
P
I
S
S
P
A
Site 27
S330
M
S
Y
P
L
E
S
S
P
I
S
S
P
A
Q
Site 28
S333
P
L
E
S
S
P
I
S
S
P
A
Q
L
P
P
Site 29
S334
L
E
S
S
P
I
S
S
P
A
Q
L
P
P
K
Site 30
Y342
P
A
Q
L
P
P
K
Y
Q
L
G
S
T
S
Y
Site 31
S346
P
P
K
Y
Q
L
G
S
T
S
Y
L
P
D
K
Site 32
S348
K
Y
Q
L
G
S
T
S
Y
L
P
D
K
L
P
Site 33
Y349
Y
Q
L
G
S
T
S
Y
L
P
D
K
L
P
K
Site 34
S371
A
E
L
P
G
S
L
S
L
S
S
A
E
P
Q
Site 35
S373
L
P
G
S
L
S
L
S
S
A
E
P
Q
P
A
Site 36
S374
P
G
S
L
S
L
S
S
A
E
P
Q
P
A
S
Site 37
S381
S
A
E
P
Q
P
A
S
P
Q
P
A
A
A
A
Site 38
S399
D
E
A
L
L
A
K
S
P
A
N
L
S
E
A
Site 39
S404
A
K
S
P
A
N
L
S
E
A
L
C
A
A
N
Site 40
S460
L
Q
A
Q
P
Q
D
S
P
G
A
G
G
P
L
Site 41
T480
H
S
L
P
P
V
F
T
S
G
L
S
S
T
T
Site 42
T486
F
T
S
G
L
S
S
T
T
L
P
R
F
H
Q
Site 43
T487
T
S
G
L
S
S
T
T
L
P
R
F
H
Q
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation