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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRIM35
Full Name:
Tripartite motif-containing protein 35
Alias:
hemopoeitic lineage switch protein 5; HLS5; KIAA1098; MAIR; TRI35; tripartite motif protein 35; tripartite motif-containing 35
Type:
DNA binding protein, DNA repair
Mass (Da):
56540
Number AA:
493
UniProt ID:
Q9UPQ4
International Prot ID:
IPI00012331
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0006917
GO:0045930
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S4
_
_
_
_
M
E
R
S
P
D
V
S
P
G
P
Site 2
S8
M
E
R
S
P
D
V
S
P
G
P
S
R
S
F
Site 3
S12
P
D
V
S
P
G
P
S
R
S
F
K
E
E
L
Site 4
S14
V
S
P
G
P
S
R
S
F
K
E
E
L
L
C
Site 5
S65
P
V
C
K
D
R
A
S
P
A
D
L
R
T
N
Site 6
T74
A
D
L
R
T
N
H
T
L
N
N
L
V
E
K
Site 7
T93
E
A
E
G
A
R
W
T
S
Y
R
F
S
R
V
Site 8
S94
A
E
G
A
R
W
T
S
Y
R
F
S
R
V
C
Site 9
Y95
E
G
A
R
W
T
S
Y
R
F
S
R
V
C
R
Site 10
S109
R
L
H
R
G
Q
L
S
L
F
C
L
E
D
K
Site 11
T140
R
V
Q
P
V
K
D
T
A
H
D
F
R
A
K
Site 12
Y169
F
W
A
M
R
R
S
Y
E
A
I
A
K
H
N
Site 13
S251
E
M
K
E
D
D
V
S
F
L
M
K
H
K
S
Site 14
S258
S
F
L
M
K
H
K
S
R
K
R
R
L
F
C
Site 15
T266
R
K
R
R
L
F
C
T
M
E
P
E
P
V
Q
Site 16
S305
S
V
E
S
V
P
F
S
F
D
P
N
T
A
A
Site 17
S316
N
T
A
A
G
W
L
S
V
S
D
D
L
T
S
Site 18
T322
L
S
V
S
D
D
L
T
S
V
T
N
H
G
Y
Site 19
S323
S
V
S
D
D
L
T
S
V
T
N
H
G
Y
R
Site 20
S340
V
E
N
P
E
R
F
S
S
A
P
C
L
L
G
Site 21
S341
E
N
P
E
R
F
S
S
A
P
C
L
L
G
S
Site 22
S352
L
L
G
S
R
V
F
S
Q
G
S
H
A
W
E
Site 23
S379
V
V
R
V
R
Q
D
S
G
A
E
G
H
S
H
Site 24
S387
G
A
E
G
H
S
H
S
C
Y
H
D
T
R
S
Site 25
Y389
E
G
H
S
H
S
C
Y
H
D
T
R
S
G
F
Site 26
Y398
D
T
R
S
G
F
W
Y
V
C
R
T
Q
G
V
Site 27
S413
E
G
D
H
C
V
T
S
D
P
A
T
S
P
L
Site 28
S440
E
C
E
E
G
E
L
S
F
Y
D
A
E
R
H
Site 29
Y442
E
E
G
E
L
S
F
Y
D
A
E
R
H
C
H
Site 30
Y451
A
E
R
H
C
H
L
Y
T
F
H
A
R
F
G
Site 31
Y463
R
F
G
E
V
R
P
Y
F
Y
L
G
G
A
R
Site 32
S486
R
I
C
P
L
H
I
S
V
K
E
E
L
D
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation