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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZFR2
Full Name:
Zinc finger RNA-binding protein 2
Alias:
K1086; KIAA1086
Type:
Mass (Da):
101362
Number AA:
939
UniProt ID:
Q9UPR6
International Prot ID:
IPI00238277
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y17
A
Q
G
G
G
P
Q
Y
S
A
Q
P
P
T
L
Site 2
S18
Q
G
G
G
P
Q
Y
S
A
Q
P
P
T
L
P
Site 3
T23
Q
Y
S
A
Q
P
P
T
L
P
L
P
T
V
G
Site 4
S32
P
L
P
T
V
G
A
S
Y
T
A
Q
P
T
P
Site 5
T34
P
T
V
G
A
S
Y
T
A
Q
P
T
P
G
M
Site 6
T38
A
S
Y
T
A
Q
P
T
P
G
M
D
P
A
V
Site 7
Y57
P
P
A
A
P
A
G
Y
G
G
Y
Q
P
H
S
Site 8
Y60
A
P
A
G
Y
G
G
Y
Q
P
H
S
G
Q
D
Site 9
Y70
H
S
G
Q
D
F
A
Y
G
S
R
P
Q
E
P
Site 10
S72
G
Q
D
F
A
Y
G
S
R
P
Q
E
P
V
P
Site 11
T80
R
P
Q
E
P
V
P
T
A
T
T
M
A
T
Y
Site 12
T86
P
T
A
T
T
M
A
T
Y
Q
D
S
Y
S
Y
Site 13
Y87
T
A
T
T
M
A
T
Y
Q
D
S
Y
S
Y
G
Site 14
S90
T
M
A
T
Y
Q
D
S
Y
S
Y
G
Q
S
A
Site 15
Y91
M
A
T
Y
Q
D
S
Y
S
Y
G
Q
S
A
A
Site 16
S92
A
T
Y
Q
D
S
Y
S
Y
G
Q
S
A
A
A
Site 17
S96
D
S
Y
S
Y
G
Q
S
A
A
A
R
S
Y
E
Site 18
S101
G
Q
S
A
A
A
R
S
Y
E
D
R
P
Y
F
Site 19
Y102
Q
S
A
A
A
R
S
Y
E
D
R
P
Y
F
Q
Site 20
Y107
R
S
Y
E
D
R
P
Y
F
Q
S
A
A
L
Q
Site 21
S110
E
D
R
P
Y
F
Q
S
A
A
L
Q
S
G
R
Site 22
S115
F
Q
S
A
A
L
Q
S
G
R
M
T
A
A
D
Site 23
T119
A
L
Q
S
G
R
M
T
A
A
D
S
G
Q
P
Site 24
S123
G
R
M
T
A
A
D
S
G
Q
P
G
T
Q
E
Site 25
S136
Q
E
A
C
G
Q
P
S
P
H
G
S
H
S
H
Site 26
S140
G
Q
P
S
P
H
G
S
H
S
H
A
Q
P
P
Site 27
S142
P
S
P
H
G
S
H
S
H
A
Q
P
P
Q
Q
Site 28
S160
V
E
S
G
Q
P
A
S
T
L
S
S
G
Y
T
Site 29
T161
E
S
G
Q
P
A
S
T
L
S
S
G
Y
T
Y
Site 30
S164
Q
P
A
S
T
L
S
S
G
Y
T
Y
P
T
A
Site 31
Y166
A
S
T
L
S
S
G
Y
T
Y
P
T
A
T
G
Site 32
T167
S
T
L
S
S
G
Y
T
Y
P
T
A
T
G
V
Site 33
Y168
T
L
S
S
G
Y
T
Y
P
T
A
T
G
V
Q
Site 34
S178
A
T
G
V
Q
P
E
S
S
A
S
I
M
T
S
Site 35
S179
T
G
V
Q
P
E
S
S
A
S
I
M
T
S
Y
Site 36
S181
V
Q
P
E
S
S
A
S
I
M
T
S
Y
P
P
Site 37
T184
E
S
S
A
S
I
M
T
S
Y
P
P
P
S
Y
Site 38
S185
S
S
A
S
I
M
T
S
Y
P
P
P
S
Y
N
Site 39
Y186
S
A
S
I
M
T
S
Y
P
P
P
S
Y
N
P
Site 40
S190
M
T
S
Y
P
P
P
S
Y
N
P
T
C
T
A
Site 41
Y191
T
S
Y
P
P
P
S
Y
N
P
T
C
T
A
Y
Site 42
T194
P
P
P
S
Y
N
P
T
C
T
A
Y
T
A
P
Site 43
T196
P
S
Y
N
P
T
C
T
A
Y
T
A
P
S
Y
Site 44
Y198
Y
N
P
T
C
T
A
Y
T
A
P
S
Y
P
N
Site 45
S202
C
T
A
Y
T
A
P
S
Y
P
N
Y
D
A
S
Site 46
Y203
T
A
Y
T
A
P
S
Y
P
N
Y
D
A
S
V
Site 47
Y206
T
A
P
S
Y
P
N
Y
D
A
S
V
Y
S
A
Site 48
S209
S
Y
P
N
Y
D
A
S
V
Y
S
A
A
S
P
Site 49
Y211
P
N
Y
D
A
S
V
Y
S
A
A
S
P
F
Y
Site 50
S212
N
Y
D
A
S
V
Y
S
A
A
S
P
F
Y
P
Site 51
S215
A
S
V
Y
S
A
A
S
P
F
Y
P
P
A
Q
Site 52
Y218
Y
S
A
A
S
P
F
Y
P
P
A
Q
P
P
P
Site 53
S242
Y
C
D
I
C
K
I
S
C
A
G
P
Q
T
Y
Site 54
S244
P
A
P
A
G
S
G
S
S
P
R
A
D
S
K
Site 55
S245
A
P
A
G
S
G
S
S
P
R
A
D
S
K
P
Site 56
S250
G
S
S
P
R
A
D
S
K
P
P
L
P
S
K
Site 57
S256
D
S
K
P
P
L
P
S
K
L
P
R
P
K
A
Site 58
S279
Y
C
D
I
C
K
I
S
C
A
G
P
Q
T
Y
Site 59
T285
I
S
C
A
G
P
Q
T
Y
R
E
H
L
G
G
Site 60
Y286
S
C
A
G
P
Q
T
Y
R
E
H
L
G
G
Q
Site 61
S311
T
G
V
Q
P
N
G
S
P
R
G
V
Q
A
Q
Site 62
Y334
S
C
T
G
A
D
A
Y
A
A
H
I
R
G
S
Site 63
T366
T
L
E
P
A
L
A
T
E
S
P
P
G
A
E
Site 64
S368
E
P
A
L
A
T
E
S
P
P
G
A
E
A
K
Site 65
T377
P
G
A
E
A
K
P
T
S
P
T
G
P
S
V
Site 66
S378
G
A
E
A
K
P
T
S
P
T
G
P
S
V
C
Site 67
S383
P
T
S
P
T
G
P
S
V
C
A
S
S
R
P
Site 68
S387
T
G
P
S
V
C
A
S
S
R
P
A
L
A
K
Site 69
Y454
A
Q
P
V
G
P
E
Y
V
E
E
V
F
S
D
Site 70
S460
E
Y
V
E
E
V
F
S
D
E
G
R
V
L
R
Site 71
Y496
G
R
R
H
R
L
Q
Y
R
K
K
V
N
P
D
Site 72
T508
N
P
D
L
P
I
A
T
E
P
S
S
R
A
R
Site 73
S511
L
P
I
A
T
E
P
S
S
R
A
R
K
V
L
Site 74
S512
P
I
A
T
E
P
S
S
R
A
R
K
V
L
E
Site 75
S573
L
L
M
G
R
P
E
S
P
A
S
A
P
L
Q
Site 76
S576
G
R
P
E
S
P
A
S
A
P
L
Q
P
G
R
Site 77
S587
Q
P
G
R
R
P
A
S
S
D
D
R
H
V
M
Site 78
S588
P
G
R
R
P
A
S
S
D
D
R
H
V
M
C
Site 79
Y601
M
C
K
H
A
T
I
Y
P
T
E
Q
E
L
L
Site 80
S615
L
A
V
Q
R
A
V
S
H
A
E
R
A
L
K
Site 81
T627
A
L
K
L
V
S
D
T
L
A
E
E
D
R
G
Site 82
S644
E
E
E
G
D
K
R
S
S
V
A
P
Q
T
R
Site 83
S645
E
E
G
D
K
R
S
S
V
A
P
Q
T
R
V
Site 84
T650
R
S
S
V
A
P
Q
T
R
V
L
K
G
V
M
Site 85
S687
C
S
E
K
P
T
H
S
L
L
R
R
I
A
Q
Site 86
Y708
Q
M
V
T
E
D
E
Y
E
V
S
S
D
P
E
Site 87
S711
T
E
D
E
Y
E
V
S
S
D
P
E
A
N
I
Site 88
S712
E
D
E
Y
E
V
S
S
D
P
E
A
N
I
V
Site 89
S721
P
E
A
N
I
V
I
S
S
C
E
E
P
R
M
Site 90
S722
E
A
N
I
V
I
S
S
C
E
E
P
R
M
Q
Site 91
T731
E
E
P
R
M
Q
V
T
I
S
V
T
S
P
L
Site 92
S733
P
R
M
Q
V
T
I
S
V
T
S
P
L
M
R
Site 93
S736
Q
V
T
I
S
V
T
S
P
L
M
R
E
D
P
Site 94
S744
P
L
M
R
E
D
P
S
T
D
P
G
V
E
E
Site 95
T745
L
M
R
E
D
P
S
T
D
P
G
V
E
E
P
Site 96
S761
A
D
A
G
D
V
L
S
P
K
K
C
L
E
S
Site 97
S768
S
P
K
K
C
L
E
S
L
A
A
L
R
H
A
Site 98
T804
D
L
C
R
R
V
P
T
W
G
A
L
P
A
W
Site 99
T862
D
P
C
E
R
D
Q
T
D
A
L
E
P
M
T
Site 100
T877
L
Q
E
R
E
D
V
T
A
S
A
Q
H
A
L
Site 101
T892
R
M
L
A
F
R
Q
T
H
K
V
L
G
M
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation