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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRAK1
Full Name:
Trafficking kinesin-binding protein 1
Alias:
106 kDa O-GlcNAc transferase-interacting protein; KIAA1042; OGT(O Glc NAc transferase) interacting protein 106 KDa; OIP106; Trafficking protein, kinesin binding 1
Type:
Mass (Da):
106040
Number AA:
953
UniProt ID:
Q9UPV9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
GO:0005634
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006493
GO:0006605
GO:0006357
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y54
L
E
E
Q
L
P
H
Y
K
L
R
A
D
T
I
Site 2
Y62
K
L
R
A
D
T
I
Y
G
Y
D
H
D
D
W
Site 3
Y64
R
A
D
T
I
Y
G
Y
D
H
D
D
W
L
H
Site 4
T72
D
H
D
D
W
L
H
T
P
L
I
S
P
D
A
Site 5
T84
P
D
A
N
I
D
L
T
T
E
Q
I
E
E
T
Site 6
T91
T
T
E
Q
I
E
E
T
L
K
Y
F
L
L
C
Site 7
Y94
Q
I
E
E
T
L
K
Y
F
L
L
C
A
E
R
Site 8
T106
A
E
R
V
G
Q
M
T
K
T
Y
N
D
I
D
Site 9
T108
R
V
G
Q
M
T
K
T
Y
N
D
I
D
A
V
Site 10
Y109
V
G
Q
M
T
K
T
Y
N
D
I
D
A
V
T
Site 11
T142
S
L
L
K
K
N
K
T
L
T
E
R
N
E
L
Site 12
T144
L
K
K
N
K
T
L
T
E
R
N
E
L
L
E
Site 13
S162
E
H
I
R
E
E
V
S
Q
L
R
H
E
L
S
Site 14
S169
S
Q
L
R
H
E
L
S
M
K
D
E
L
L
Q
Site 15
S180
E
L
L
Q
F
Y
T
S
A
A
E
E
S
E
P
Site 16
S185
Y
T
S
A
A
E
E
S
E
P
E
S
V
C
S
Site 17
S189
A
E
E
S
E
P
E
S
V
C
S
T
P
L
K
Site 18
S192
S
E
P
E
S
V
C
S
T
P
L
K
R
N
E
Site 19
T193
E
P
E
S
V
C
S
T
P
L
K
R
N
E
S
Site 20
S200
T
P
L
K
R
N
E
S
S
S
S
V
Q
N
Y
Site 21
S202
L
K
R
N
E
S
S
S
S
V
Q
N
Y
F
H
Site 22
S203
K
R
N
E
S
S
S
S
V
Q
N
Y
F
H
L
Site 23
Y207
S
S
S
S
V
Q
N
Y
F
H
L
D
S
L
Q
Site 24
S212
Q
N
Y
F
H
L
D
S
L
Q
K
K
L
K
D
Site 25
S229
E
E
N
V
V
L
R
S
E
A
S
Q
L
K
T
Site 26
S232
V
V
L
R
S
E
A
S
Q
L
K
T
E
T
I
Site 27
T236
S
E
A
S
Q
L
K
T
E
T
I
T
Y
E
E
Site 28
Y241
L
K
T
E
T
I
T
Y
E
E
K
E
Q
Q
L
Site 29
S265
D
A
N
V
Q
I
A
S
I
S
E
E
L
A
K
Site 30
T285
A
R
Q
Q
E
E
I
T
H
L
L
S
Q
I
V
Site 31
S289
E
E
I
T
H
L
L
S
Q
I
V
D
L
Q
K
Site 32
T323
K
D
A
Q
R
Q
L
T
A
E
L
R
E
L
E
Site 33
Y333
L
R
E
L
E
D
K
Y
A
E
C
M
E
M
L
Site 34
T354
L
K
N
L
R
N
K
T
M
P
N
T
T
S
R
Site 35
T358
R
N
K
T
M
P
N
T
T
S
R
R
Y
H
S
Site 36
T359
N
K
T
M
P
N
T
T
S
R
R
Y
H
S
L
Site 37
S360
K
T
M
P
N
T
T
S
R
R
Y
H
S
L
G
Site 38
Y363
P
N
T
T
S
R
R
Y
H
S
L
G
L
F
P
Site 39
S365
T
T
S
R
R
Y
H
S
L
G
L
F
P
M
D
Site 40
T381
L
A
A
E
I
E
G
T
M
R
K
E
L
Q
L
Site 41
S393
L
Q
L
E
E
A
E
S
P
D
I
T
H
Q
K
Site 42
T397
E
A
E
S
P
D
I
T
H
Q
K
R
V
F
E
Site 43
T405
H
Q
K
R
V
F
E
T
V
R
N
I
N
Q
V
Site 44
S417
N
Q
V
V
K
Q
R
S
L
T
P
S
P
M
N
Site 45
T419
V
V
K
Q
R
S
L
T
P
S
P
M
N
I
P
Site 46
S421
K
Q
R
S
L
T
P
S
P
M
N
I
P
G
S
Site 47
S428
S
P
M
N
I
P
G
S
N
Q
S
S
A
M
N
Site 48
S431
N
I
P
G
S
N
Q
S
S
A
M
N
S
L
L
Site 49
S432
I
P
G
S
N
Q
S
S
A
M
N
S
L
L
S
Site 50
S436
N
Q
S
S
A
M
N
S
L
L
S
S
C
V
S
Site 51
S439
S
A
M
N
S
L
L
S
S
C
V
S
T
P
R
Site 52
S440
A
M
N
S
L
L
S
S
C
V
S
T
P
R
S
Site 53
S443
S
L
L
S
S
C
V
S
T
P
R
S
S
F
Y
Site 54
S447
S
C
V
S
T
P
R
S
S
F
Y
G
S
D
I
Site 55
S448
C
V
S
T
P
R
S
S
F
Y
G
S
D
I
G
Site 56
Y450
S
T
P
R
S
S
F
Y
G
S
D
I
G
N
V
Site 57
S452
P
R
S
S
F
Y
G
S
D
I
G
N
V
V
L
Site 58
S481
D
L
G
N
D
E
R
S
K
K
P
G
T
P
G
Site 59
T486
E
R
S
K
K
P
G
T
P
G
T
P
G
S
H
Site 60
T489
K
K
P
G
T
P
G
T
P
G
S
H
D
L
E
Site 61
S492
G
T
P
G
T
P
G
S
H
D
L
E
T
A
L
Site 62
T497
P
G
S
H
D
L
E
T
A
L
R
R
L
S
L
Site 63
S503
E
T
A
L
R
R
L
S
L
R
R
E
N
Y
L
Site 64
Y509
L
S
L
R
R
E
N
Y
L
S
E
R
R
F
F
Site 65
S511
L
R
R
E
N
Y
L
S
E
R
R
F
F
E
E
Site 66
S537
K
G
E
L
R
S
G
S
L
T
P
T
E
S
I
Site 67
T539
E
L
R
S
G
S
L
T
P
T
E
S
I
M
S
Site 68
T541
R
S
G
S
L
T
P
T
E
S
I
M
S
L
G
Site 69
S543
G
S
L
T
P
T
E
S
I
M
S
L
G
T
H
Site 70
S546
T
P
T
E
S
I
M
S
L
G
T
H
S
R
F
Site 71
T549
E
S
I
M
S
L
G
T
H
S
R
F
S
E
F
Site 72
S554
L
G
T
H
S
R
F
S
E
F
T
G
F
S
G
Site 73
T557
H
S
R
F
S
E
F
T
G
F
S
G
M
S
F
Site 74
S560
F
S
E
F
T
G
F
S
G
M
S
F
S
S
R
Site 75
S563
F
T
G
F
S
G
M
S
F
S
S
R
S
Y
L
Site 76
S565
G
F
S
G
M
S
F
S
S
R
S
Y
L
P
E
Site 77
S566
F
S
G
M
S
F
S
S
R
S
Y
L
P
E
K
Site 78
S568
G
M
S
F
S
S
R
S
Y
L
P
E
K
L
Q
Site 79
Y569
M
S
F
S
S
R
S
Y
L
P
E
K
L
Q
I
Site 80
T585
K
P
L
E
G
S
A
T
L
H
H
W
Q
Q
L
Site 81
T609
D
P
R
P
G
V
V
T
K
G
F
R
T
L
D
Site 82
Y623
D
V
D
L
D
E
V
Y
C
L
N
D
F
E
E
Site 83
T633
N
D
F
E
E
D
D
T
G
D
H
I
S
L
P
Site 84
S638
D
D
T
G
D
H
I
S
L
P
R
L
A
T
S
Site 85
T644
I
S
L
P
R
L
A
T
S
T
P
V
Q
H
P
Site 86
T646
L
P
R
L
A
T
S
T
P
V
Q
H
P
E
T
Site 87
T653
T
P
V
Q
H
P
E
T
S
A
H
H
P
G
K
Site 88
T665
P
G
K
C
M
S
Q
T
N
S
T
F
T
F
T
Site 89
T670
S
Q
T
N
S
T
F
T
F
T
T
C
R
I
L
Site 90
T672
T
N
S
T
F
T
F
T
T
C
R
I
L
H
P
Site 91
S680
T
C
R
I
L
H
P
S
D
E
L
T
R
V
T
Site 92
T684
L
H
P
S
D
E
L
T
R
V
T
P
S
L
N
Site 93
T687
S
D
E
L
T
R
V
T
P
S
L
N
S
A
P
Site 94
S689
E
L
T
R
V
T
P
S
L
N
S
A
P
T
P
Site 95
T695
P
S
L
N
S
A
P
T
P
A
C
G
S
T
S
Site 96
S700
A
P
T
P
A
C
G
S
T
S
H
L
K
S
T
Site 97
S702
T
P
A
C
G
S
T
S
H
L
K
S
T
P
V
Site 98
S706
G
S
T
S
H
L
K
S
T
P
V
A
T
P
C
Site 99
T707
S
T
S
H
L
K
S
T
P
V
A
T
P
C
T
Site 100
T711
L
K
S
T
P
V
A
T
P
C
T
P
R
R
L
Site 101
T714
T
P
V
A
T
P
C
T
P
R
R
L
S
L
A
Site 102
S719
P
C
T
P
R
R
L
S
L
A
E
S
F
T
N
Site 103
S723
R
R
L
S
L
A
E
S
F
T
N
T
R
E
S
Site 104
T725
L
S
L
A
E
S
F
T
N
T
R
E
S
T
T
Site 105
T727
L
A
E
S
F
T
N
T
R
E
S
T
T
T
M
Site 106
S730
S
F
T
N
T
R
E
S
T
T
T
M
S
T
S
Site 107
T731
F
T
N
T
R
E
S
T
T
T
M
S
T
S
L
Site 108
T733
N
T
R
E
S
T
T
T
M
S
T
S
L
G
L
Site 109
S750
L
L
K
E
R
G
I
S
A
A
V
Y
D
P
Q
Site 110
Y754
R
G
I
S
A
A
V
Y
D
P
Q
S
W
D
R
Site 111
S758
A
A
V
Y
D
P
Q
S
W
D
R
A
G
R
G
Site 112
S766
W
D
R
A
G
R
G
S
L
L
H
S
Y
T
P
Site 113
S770
G
R
G
S
L
L
H
S
Y
T
P
K
M
A
V
Site 114
S780
P
K
M
A
V
I
P
S
T
P
P
N
S
P
M
Site 115
T781
K
M
A
V
I
P
S
T
P
P
N
S
P
M
Q
Site 116
S785
I
P
S
T
P
P
N
S
P
M
Q
T
P
T
S
Site 117
T789
P
P
N
S
P
M
Q
T
P
T
S
S
P
P
S
Site 118
T791
N
S
P
M
Q
T
P
T
S
S
P
P
S
F
E
Site 119
S792
S
P
M
Q
T
P
T
S
S
P
P
S
F
E
F
Site 120
S793
P
M
Q
T
P
T
S
S
P
P
S
F
E
F
K
Site 121
S796
T
P
T
S
S
P
P
S
F
E
F
K
C
T
S
Site 122
T802
P
S
F
E
F
K
C
T
S
P
P
Y
D
N
F
Site 123
S803
S
F
E
F
K
C
T
S
P
P
Y
D
N
F
L
Site 124
Y806
F
K
C
T
S
P
P
Y
D
N
F
L
A
S
K
Site 125
S812
P
Y
D
N
F
L
A
S
K
P
A
S
S
I
L
Site 126
S816
F
L
A
S
K
P
A
S
S
I
L
R
E
V
R
Site 127
S817
L
A
S
K
P
A
S
S
I
L
R
E
V
R
E
Site 128
S829
V
R
E
K
N
V
R
S
S
E
S
Q
T
D
V
Site 129
S830
R
E
K
N
V
R
S
S
E
S
Q
T
D
V
S
Site 130
S832
K
N
V
R
S
S
E
S
Q
T
D
V
S
V
S
Site 131
T834
V
R
S
S
E
S
Q
T
D
V
S
V
S
N
L
Site 132
S837
S
E
S
Q
T
D
V
S
V
S
N
L
N
L
V
Site 133
T865
S
G
R
A
H
V
P
T
L
T
E
E
Q
G
P
Site 134
T867
R
A
H
V
P
T
L
T
E
E
Q
G
P
L
L
Site 135
S912
I
G
G
L
Q
L
N
S
G
I
R
R
N
R
S
Site 136
S919
S
G
I
R
R
N
R
S
F
P
T
M
V
G
S
Site 137
T922
R
R
N
R
S
F
P
T
M
V
G
S
S
M
Q
Site 138
S926
S
F
P
T
M
V
G
S
S
M
Q
M
K
A
P
Site 139
S947
I
L
M
G
A
K
L
S
K
Q
T
S
L
R
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation