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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FOXJ3
Full Name:
Forkhead box protein J3
Alias:
Forkhead box J3; KIAA1041
Type:
DNA binding protein
Mass (Da):
68928
Number AA:
622
UniProt ID:
Q9UPW0
International Prot ID:
IPI00010426
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006350
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
Q
A
C
P
S
V
T
S
L
R
M
T
S
E
L
Site 2
T17
S
V
T
S
L
R
M
T
S
E
L
E
S
S
L
Site 3
S18
V
T
S
L
R
M
T
S
E
L
E
S
S
L
T
Site 4
S22
R
M
T
S
E
L
E
S
S
L
T
S
M
D
W
Site 5
S23
M
T
S
E
L
E
S
S
L
T
S
M
D
W
L
Site 6
T25
S
E
L
E
S
S
L
T
S
M
D
W
L
P
Q
Site 7
S26
E
L
E
S
S
L
T
S
M
D
W
L
P
Q
L
Site 8
S42
M
R
A
A
I
Q
K
S
D
A
T
Q
N
A
H
Site 9
T45
A
I
Q
K
S
D
A
T
Q
N
A
H
G
T
G
Site 10
T64
N
A
L
L
D
P
N
T
T
L
D
Q
E
E
V
Site 11
Y81
H
K
D
G
K
P
P
Y
S
Y
A
S
L
I
T
Site 12
S82
K
D
G
K
P
P
Y
S
Y
A
S
L
I
T
F
Site 13
Y83
D
G
K
P
P
Y
S
Y
A
S
L
I
T
F
A
Site 14
S93
L
I
T
F
A
I
N
S
S
P
K
K
K
M
T
Site 15
S94
I
T
F
A
I
N
S
S
P
K
K
K
M
T
L
Site 16
T100
S
S
P
K
K
K
M
T
L
S
E
I
Y
Q
W
Site 17
Y114
W
I
C
D
N
F
P
Y
Y
R
E
A
G
S
G
Site 18
Y115
I
C
D
N
F
P
Y
Y
R
E
A
G
S
G
W
Site 19
S125
A
G
S
G
W
K
N
S
I
R
H
N
L
S
L
Site 20
S131
N
S
I
R
H
N
L
S
L
N
K
C
F
L
K
Site 21
S142
C
F
L
K
V
P
R
S
K
D
D
P
G
K
G
Site 22
S173
R
P
K
K
R
A
R
S
V
E
R
A
S
T
P
Site 23
S178
A
R
S
V
E
R
A
S
T
P
Y
S
I
D
S
Site 24
T179
R
S
V
E
R
A
S
T
P
Y
S
I
D
S
D
Site 25
Y181
V
E
R
A
S
T
P
Y
S
I
D
S
D
S
L
Site 26
S182
E
R
A
S
T
P
Y
S
I
D
S
D
S
L
G
Site 27
S185
S
T
P
Y
S
I
D
S
D
S
L
G
M
E
C
Site 28
Y214
V
T
N
K
V
T
L
Y
N
T
D
Q
D
G
S
Site 29
S221
Y
N
T
D
Q
D
G
S
D
S
P
R
S
S
L
Site 30
S223
T
D
Q
D
G
S
D
S
P
R
S
S
L
N
N
Site 31
S226
D
G
S
D
S
P
R
S
S
L
N
N
S
L
S
Site 32
S227
G
S
D
S
P
R
S
S
L
N
N
S
L
S
D
Site 33
S231
P
R
S
S
L
N
N
S
L
S
D
Q
S
L
A
Site 34
S233
S
S
L
N
N
S
L
S
D
Q
S
L
A
S
V
Site 35
S236
N
N
S
L
S
D
Q
S
L
A
S
V
N
L
N
Site 36
S247
V
N
L
N
S
V
G
S
V
H
S
Y
T
P
V
Site 37
S250
N
S
V
G
S
V
H
S
Y
T
P
V
T
S
H
Site 38
Y251
S
V
G
S
V
H
S
Y
T
P
V
T
S
H
P
Site 39
T252
V
G
S
V
H
S
Y
T
P
V
T
S
H
P
E
Site 40
T255
V
H
S
Y
T
P
V
T
S
H
P
E
S
V
S
Site 41
S256
H
S
Y
T
P
V
T
S
H
P
E
S
V
S
Q
Site 42
S260
P
V
T
S
H
P
E
S
V
S
Q
S
L
T
P
Site 43
S262
T
S
H
P
E
S
V
S
Q
S
L
T
P
Q
Q
Site 44
S264
H
P
E
S
V
S
Q
S
L
T
P
Q
Q
Q
P
Site 45
T266
E
S
V
S
Q
S
L
T
P
Q
Q
Q
P
Q
Y
Site 46
Y273
T
P
Q
Q
Q
P
Q
Y
N
L
P
E
R
D
K
Site 47
S285
R
D
K
Q
L
L
F
S
E
Y
N
F
E
D
L
Site 48
S293
E
Y
N
F
E
D
L
S
A
S
F
R
S
L
Y
Site 49
S295
N
F
E
D
L
S
A
S
F
R
S
L
Y
K
S
Site 50
S298
D
L
S
A
S
F
R
S
L
Y
K
S
V
F
E
Site 51
Y300
S
A
S
F
R
S
L
Y
K
S
V
F
E
Q
S
Site 52
S302
S
F
R
S
L
Y
K
S
V
F
E
Q
S
L
S
Site 53
S307
Y
K
S
V
F
E
Q
S
L
S
Q
Q
G
L
M
Site 54
S309
S
V
F
E
Q
S
L
S
Q
Q
G
L
M
N
I
Site 55
S318
Q
G
L
M
N
I
P
S
E
S
S
Q
Q
S
H
Site 56
S320
L
M
N
I
P
S
E
S
S
Q
Q
S
H
T
S
Site 57
S321
M
N
I
P
S
E
S
S
Q
Q
S
H
T
S
C
Site 58
S324
P
S
E
S
S
Q
Q
S
H
T
S
C
T
Y
Q
Site 59
T326
E
S
S
Q
Q
S
H
T
S
C
T
Y
Q
H
S
Site 60
S327
S
S
Q
Q
S
H
T
S
C
T
Y
Q
H
S
P
Site 61
T329
Q
Q
S
H
T
S
C
T
Y
Q
H
S
P
S
S
Site 62
Y330
Q
S
H
T
S
C
T
Y
Q
H
S
P
S
S
T
Site 63
S333
T
S
C
T
Y
Q
H
S
P
S
S
T
V
S
T
Site 64
S335
C
T
Y
Q
H
S
P
S
S
T
V
S
T
H
P
Site 65
S336
T
Y
Q
H
S
P
S
S
T
V
S
T
H
P
H
Site 66
T337
Y
Q
H
S
P
S
S
T
V
S
T
H
P
H
S
Site 67
S339
H
S
P
S
S
T
V
S
T
H
P
H
S
N
Q
Site 68
T340
S
P
S
S
T
V
S
T
H
P
H
S
N
Q
S
Site 69
S344
T
V
S
T
H
P
H
S
N
Q
S
S
L
S
N
Site 70
S347
T
H
P
H
S
N
Q
S
S
L
S
N
S
H
G
Site 71
S348
H
P
H
S
N
Q
S
S
L
S
N
S
H
G
S
Site 72
S350
H
S
N
Q
S
S
L
S
N
S
H
G
S
G
L
Site 73
S352
N
Q
S
S
L
S
N
S
H
G
S
G
L
N
T
Site 74
S355
S
L
S
N
S
H
G
S
G
L
N
T
T
G
S
Site 75
T359
S
H
G
S
G
L
N
T
T
G
S
N
S
V
A
Site 76
T360
H
G
S
G
L
N
T
T
G
S
N
S
V
A
Q
Site 77
S362
S
G
L
N
T
T
G
S
N
S
V
A
Q
V
S
Site 78
S364
L
N
T
T
G
S
N
S
V
A
Q
V
S
L
S
Site 79
S369
S
N
S
V
A
Q
V
S
L
S
H
P
Q
M
H
Site 80
S371
S
V
A
Q
V
S
L
S
H
P
Q
M
H
P
Q
Site 81
S380
P
Q
M
H
P
Q
P
S
P
H
P
P
H
R
P
Site 82
S397
L
P
Q
H
P
Q
R
S
P
H
P
A
P
H
P
Site 83
S408
A
P
H
P
Q
Q
H
S
Q
L
Q
S
P
H
P
Site 84
S412
Q
Q
H
S
Q
L
Q
S
P
H
P
Q
H
P
S
Site 85
S419
S
P
H
P
Q
H
P
S
P
H
Q
H
I
Q
H
Site 86
S447
P
P
P
P
Q
Q
V
S
C
N
S
G
V
S
N
Site 87
Y457
S
G
V
S
N
D
W
Y
A
T
L
D
M
L
K
Site 88
S471
K
E
S
C
R
I
A
S
S
V
N
W
S
D
V
Site 89
S472
E
S
C
R
I
A
S
S
V
N
W
S
D
V
D
Site 90
S476
I
A
S
S
V
N
W
S
D
V
D
L
S
Q
F
Site 91
S489
Q
F
Q
G
L
M
E
S
M
R
Q
A
D
L
K
Site 92
S499
Q
A
D
L
K
N
W
S
L
D
Q
V
Q
F
A
Site 93
T517
S
S
L
N
Q
F
F
T
Q
T
G
L
I
H
S
Site 94
S524
T
Q
T
G
L
I
H
S
Q
S
N
V
Q
Q
N
Site 95
S543
A
M
H
P
T
K
P
S
Q
H
I
G
T
G
N
Site 96
Y552
H
I
G
T
G
N
L
Y
I
D
S
R
Q
N
L
Site 97
S555
T
G
N
L
Y
I
D
S
R
Q
N
L
P
P
S
Site 98
S562
S
R
Q
N
L
P
P
S
V
M
P
P
P
G
Y
Site 99
Y569
S
V
M
P
P
P
G
Y
P
H
I
P
Q
A
L
Site 100
S577
P
H
I
P
Q
A
L
S
T
P
G
T
T
M
A
Site 101
T578
H
I
P
Q
A
L
S
T
P
G
T
T
M
A
G
Site 102
T581
Q
A
L
S
T
P
G
T
T
M
A
G
H
H
R
Site 103
S606
Q
A
F
Q
M
R
R
S
L
P
P
D
D
I
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation