PhosphoNET

           
Protein Info 
   
Short Name:  SLC7A11
Full Name:  Solute carrier family 7 member 11
Alias:  amino acid transport system xc-; calcium channel blocker resistance protein CCBR1; CCBR1; cystine/glutamate transporter; solute carrier family 7 (cationic amino acid transporter, y+ system) member 11; solute carrier family 7, (cationic amino acid transporter, y+ system) member 11; xCT
Type:  Transporter
Mass (Da):  55423
Number AA:  501
UniProt ID:  Q9UPY5
International Prot ID:  IPI00010474
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016021  GO:0005886   Uniprot OncoNet
Molecular Function:  GO:0015327     PhosphoSite+ KinaseNET
Biological Process:  GO:0006865  GO:0009636  GO:0055085 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S8MVRKPVVSTISKGGY
Site 2S11KPVVSTISKGGYLQG
Site 3Y15STISKGGYLQGNVNG
Site 4S26NVNGRLPSLGNKEPP
Site 5T73PKGVLQNTGSVGMSL
Site 6T103SYAELGTTIKKSGGH
Site 7S107LGTTIKKSGGHYTYI
Site 8Y111IKKSGGHYTYILEVF
Site 9S226QNFKDAFSGRDSSIT
Site 10S230DAFSGRDSSITRLPL
Site 11S231AFSGRDSSITRLPLA
Site 12T233SGRDSSITRLPLAFY
Site 13S346SRLFYVASREGHLPE
Site 14S356GHLPEILSMIHVRKH
Site 15Y412AGLIYLRYKCPDMHR
Site 16S481PRWFRIMSEKITRTL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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