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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WASF3
Full Name:
Wiskott-Aldrich syndrome protein family member 3
Alias:
Verprolin; WASP-family 3; WAVE-3
Type:
Cytoskeleton protein
Mass (Da):
55293
Number AA:
502
UniProt ID:
Q9UPY6
International Prot ID:
IPI00299003
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
Uniprot
OncoNet
Molecular Function:
GO:0003779
PhosphoSite+
KinaseNET
Biological Process:
GO:0030041
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S42
A
A
I
I
R
Q
L
S
S
L
S
K
H
A
E
Site 2
S43
A
I
I
R
Q
L
S
S
L
S
K
H
A
E
D
Site 3
S45
I
R
Q
L
S
S
L
S
K
H
A
E
D
I
F
Site 4
Y63
F
N
E
A
N
N
F
Y
I
R
A
N
S
L
Q
Site 5
S68
N
F
Y
I
R
A
N
S
L
Q
D
R
I
D
R
Site 6
T81
D
R
L
A
V
K
V
T
Q
L
D
S
T
V
E
Site 7
T86
K
V
T
Q
L
D
S
T
V
E
E
V
S
L
Q
Site 8
S91
D
S
T
V
E
E
V
S
L
Q
D
I
N
M
K
Site 9
S103
N
M
K
K
A
F
K
S
S
T
V
Q
D
Q
Q
Site 10
T105
K
K
A
F
K
S
S
T
V
Q
D
Q
Q
V
V
Site 11
S113
V
Q
D
Q
Q
V
V
S
K
N
S
I
P
N
P
Site 12
Y125
P
N
P
V
A
D
I
Y
N
Q
S
D
K
P
P
Site 13
S128
V
A
D
I
Y
N
Q
S
D
K
P
P
P
L
N
Site 14
T138
P
P
P
L
N
I
L
T
P
Y
R
D
D
K
K
Site 15
Y151
K
K
D
G
L
K
F
Y
T
D
P
S
Y
F
F
Site 16
T152
K
D
G
L
K
F
Y
T
D
P
S
Y
F
F
D
Site 17
Y156
K
F
Y
T
D
P
S
Y
F
F
D
L
W
K
E
Site 18
T169
K
E
K
M
L
Q
D
T
E
D
K
R
K
E
K
Site 19
T188
E
Q
K
R
I
D
G
T
T
R
E
V
K
K
V
Site 20
T189
Q
K
R
I
D
G
T
T
R
E
V
K
K
V
R
Site 21
S221
L
R
P
D
N
R
L
S
Q
S
V
Y
H
G
A
Site 22
S223
P
D
N
R
L
S
Q
S
V
Y
H
G
A
S
S
Site 23
Y225
N
R
L
S
Q
S
V
Y
H
G
A
S
S
E
G
Site 24
S229
Q
S
V
Y
H
G
A
S
S
E
G
S
L
S
P
Site 25
S230
S
V
Y
H
G
A
S
S
E
G
S
L
S
P
D
Site 26
S233
H
G
A
S
S
E
G
S
L
S
P
D
T
R
S
Site 27
S235
A
S
S
E
G
S
L
S
P
D
T
R
S
H
A
Site 28
T238
E
G
S
L
S
P
D
T
R
S
H
A
S
D
V
Site 29
S240
S
L
S
P
D
T
R
S
H
A
S
D
V
T
D
Site 30
T246
R
S
H
A
S
D
V
T
D
Y
S
Y
P
A
T
Site 31
Y248
H
A
S
D
V
T
D
Y
S
Y
P
A
T
P
N
Site 32
S249
A
S
D
V
T
D
Y
S
Y
P
A
T
P
N
H
Site 33
Y250
S
D
V
T
D
Y
S
Y
P
A
T
P
N
H
S
Site 34
T253
T
D
Y
S
Y
P
A
T
P
N
H
S
L
H
P
Site 35
S257
Y
P
A
T
P
N
H
S
L
H
P
Q
P
V
T
Site 36
T264
S
L
H
P
Q
P
V
T
P
S
Y
A
A
G
D
Site 37
Y267
P
Q
P
V
T
P
S
Y
A
A
G
D
V
P
P
Site 38
S279
V
P
P
H
G
P
A
S
Q
A
A
E
H
E
Y
Site 39
Y286
S
Q
A
A
E
H
E
Y
R
P
P
S
A
S
A
Site 40
S290
E
H
E
Y
R
P
P
S
A
S
A
R
H
M
A
Site 41
S292
E
Y
R
P
P
S
A
S
A
R
H
M
A
L
N
Site 42
S316
P
P
Q
A
P
E
G
S
Q
A
S
A
P
M
A
Site 43
Y337
L
P
A
Q
I
I
E
Y
Y
N
P
S
G
P
P
Site 44
Y338
P
A
Q
I
I
E
Y
Y
N
P
S
G
P
P
P
Site 45
S341
I
I
E
Y
Y
N
P
S
G
P
P
P
P
P
P
Site 46
S374
M
Q
P
P
F
P
A
S
A
S
S
T
H
A
A
Site 47
S376
P
P
F
P
A
S
A
S
S
T
H
A
A
P
P
Site 48
S377
P
F
P
A
S
A
S
S
T
H
A
A
P
P
H
Site 49
T378
F
P
A
S
A
S
S
T
H
A
A
P
P
H
P
Site 50
T393
P
S
T
G
L
L
V
T
A
P
P
P
P
G
P
Site 51
S412
P
G
P
P
G
P
G
S
S
L
S
S
S
P
M
Site 52
S413
G
P
P
G
P
G
S
S
L
S
S
S
P
M
H
Site 53
S415
P
G
P
G
S
S
L
S
S
S
P
M
H
G
P
Site 54
S416
G
P
G
S
S
L
S
S
S
P
M
H
G
P
P
Site 55
S417
P
G
S
S
L
S
S
S
P
M
H
G
P
P
V
Site 56
S438
E
P
A
Q
P
P
I
S
D
A
R
S
D
L
L
Site 57
S442
P
P
I
S
D
A
R
S
D
L
L
A
A
I
R
Site 58
T476
P
V
G
N
D
V
A
T
I
L
S
R
R
I
A
Site 59
Y486
S
R
R
I
A
V
E
Y
S
D
S
D
D
D
S
Site 60
S487
R
R
I
A
V
E
Y
S
D
S
D
D
D
S
E
Site 61
S489
I
A
V
E
Y
S
D
S
D
D
D
S
E
F
D
Site 62
S493
Y
S
D
S
D
D
D
S
E
F
D
E
N
D
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation