PhosphoNET

           
Protein Info 
   
Short Name:  SHOC2
Full Name:  Leucine-rich repeat protein SHOC-2
Alias:  Ras-binding protein Sur-8; Ras-binding sur-8; Soc2; Soc-2 suppressor of clear; Suppressor of clear; Sur8; Sur-8
Type:  Adaptor/scaffold
Mass (Da):  64888
Number AA:  582
UniProt ID:  Q9UQ13
International Prot ID:  IPI00298928
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0044424  GO:0044464 Uniprot OncoNet
Molecular Function:  GO:0005488  GO:0005515   PhosphoSite+ KinaseNET
Biological Process:  GO:0007154  GO:0007165  GO:0007166 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S11SLGKEKDSKEKDPKV
Site 2S38SGGFGKESKEKEPKT
Site 3T45SKEKEPKTKGKDAKD
Site 4S57AKDGKKDSSAAQPGV
Site 5S67AQPGVAFSVDNTIKR
Site 6T71VAFSVDNTIKRPNPA
Site 7T81RPNPAPGTRKKSSNA
Site 8S85APGTRKKSSNAEVIK
Site 9S102NKCREENSMRLDLSK
Site 10S108NSMRLDLSKRSIHIL
Site 11S111RLDLSKRSIHILPSS
Site 12S117RSIHILPSSIKELTQ
Site 13S118SIHILPSSIKELTQL
Site 14T123PSSIKELTQLTELYL
Site 15Y129LTQLTELYLYSNKLQ
Site 16Y131QLTELYLYSNKLQSL
Site 17S157TLALSENSLTSLPDS
Site 18T159ALSENSLTSLPDSLD
Site 19S160LSENSLTSLPDSLDN
Site 20S164SLTSLPDSLDNLKKL
Site 21S186NKLREIPSVVYRLDS
Site 22T205YLRFNRITTVEKDIK
Site 23T206LRFNRITTVEKDIKN
Site 24S215EKDIKNLSKLSMLSI
Site 25S218IKNLSKLSMLSIREN
Site 26S221LSKLSMLSIRENKIK
Site 27S284PDTIGNLSSLSRLGL
Site 28S285DTIGNLSSLSRLGLR
Site 29S287IGNLSSLSRLGLRYN
Site 30Y293LSRLGLRYNRLSAIP
Site 31S297GLRYNRLSAIPRSLA
Site 32S320NLENNNISTLPESLL
Site 33T321LENNNISTLPESLLS
Site 34Y346ARNCFQLYPVGGPSQ
Site 35S352LYPVGGPSQFSTIYS
Site 36T356GGPSQFSTIYSLNME
Site 37Y358PSQFSTIYSLNMEHN
Site 38S359SQFSTIYSLNMEHNR
Site 39S382FSRAKVLSKLNMKDN
Site 40S393MKDNQLTSLPLDFGT
Site 41Y469SLPNEIAYLKDLQKL
Site 42T485LTNNQLTTLPRGIGH
Site 43T497IGHLTNLTHLGLGEN
Site 44T507GLGENLLTHLPEEIG
Site 45T515HLPEEIGTLENLEEL
Site 46Y523LENLEELYLNDNPNL
Site 47S532NDNPNLHSLPFELAL
Site 48Y578FLKMQGPYRAMV___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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