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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PA2G4
Full Name:
Proliferation-associated protein 2G4
Alias:
Cell cycle protein p38-2G4 homolog; EBP1; ErbB-3 binding protein; ErbB3-binding protein 1; HG4-1; P38-2G4; Proliferation-associated 2G4, 38kDa
Type:
Nuclear receptor co-regulator; Transcription, coactivator/corepressor
Mass (Da):
43787
Number AA:
394
UniProt ID:
Q9UQ80
International Prot ID:
IPI00299000
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005730
GO:0030529
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0003700
GO:0031625
PhosphoSite+
KinaseNET
Biological Process:
GO:0007050
GO:0008283
GO:0045892
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
G
E
D
E
Q
Q
E
Site 2
T11
E
D
E
Q
Q
E
Q
T
I
A
E
D
L
V
V
Site 3
T19
I
A
E
D
L
V
V
T
K
Y
K
M
G
G
D
Site 4
Y21
E
D
L
V
V
T
K
Y
K
M
G
G
D
I
A
Site 5
S44
E
A
S
S
S
G
V
S
V
L
S
L
C
E
K
Site 6
T60
D
A
M
I
M
E
E
T
G
K
I
F
K
K
E
Site 7
S94
C
H
F
S
P
L
K
S
D
Q
D
Y
I
L
K
Site 8
Y98
P
L
K
S
D
Q
D
Y
I
L
K
E
G
D
L
Site 9
S187
T
P
I
E
G
M
L
S
H
Q
L
K
Q
H
V
Site 10
T200
H
V
I
D
G
E
K
T
I
I
Q
N
P
T
D
Site 11
T245
K
D
A
G
Q
R
T
T
I
Y
K
R
D
P
S
Site 12
Y247
A
G
Q
R
T
T
I
Y
K
R
D
P
S
K
Q
Site 13
S252
T
I
Y
K
R
D
P
S
K
Q
Y
G
L
K
M
Site 14
Y255
K
R
D
P
S
K
Q
Y
G
L
K
M
K
T
S
Site 15
T261
Q
Y
G
L
K
M
K
T
S
R
A
F
F
S
E
Site 16
S262
Y
G
L
K
M
K
T
S
R
A
F
F
S
E
V
Site 17
T279
R
F
D
A
M
P
F
T
L
R
A
F
E
D
E
Site 18
Y309
L
Q
P
F
N
V
L
Y
E
K
E
G
E
F
V
Site 19
T334
P
N
G
P
M
R
I
T
S
G
P
F
E
P
D
Site 20
S335
N
G
P
M
R
I
T
S
G
P
F
E
P
D
L
Site 21
Y343
G
P
F
E
P
D
L
Y
K
S
E
M
E
V
Q
Site 22
S345
F
E
P
D
L
Y
K
S
E
M
E
V
Q
D
A
Site 23
S360
E
L
K
A
L
L
Q
S
S
A
S
R
K
T
Q
Site 24
S361
L
K
A
L
L
Q
S
S
A
S
R
K
T
Q
K
Site 25
S363
A
L
L
Q
S
S
A
S
R
K
T
Q
K
K
K
Site 26
T366
Q
S
S
A
S
R
K
T
Q
K
K
K
K
K
K
Site 27
T377
K
K
K
K
A
S
K
T
A
E
N
A
T
S
G
Site 28
S383
K
T
A
E
N
A
T
S
G
E
T
L
E
E
N
Site 29
T386
E
N
A
T
S
G
E
T
L
E
E
N
E
A
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation