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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SPG7
Full Name:
Alias:
Spastic paraplegia 7 protein
Type:
Mass (Da):
88235
Number AA:
795
UniProt ID:
Q9UQ90
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S30
W
G
P
G
P
A
W
S
P
G
F
P
A
R
P
Site 2
Y43
R
P
G
R
G
R
P
Y
M
A
S
R
P
P
G
Site 3
S46
R
G
R
P
Y
M
A
S
R
P
P
G
D
L
A
Site 4
T98
L
W
Q
L
L
G
G
T
F
Y
F
N
T
S
R
Site 5
Y100
Q
L
L
G
G
T
F
Y
F
N
T
S
R
L
K
Site 6
T103
G
G
T
F
Y
F
N
T
S
R
L
K
Q
K
N
Site 7
S116
K
N
K
E
K
D
K
S
K
G
K
A
P
E
E
Site 8
Y138
R
E
R
D
D
Q
M
Y
R
E
R
L
R
T
L
Site 9
S166
S
T
S
G
G
S
I
S
W
N
D
F
V
H
E
Site 10
Y212
R
P
R
L
A
L
M
Y
R
M
Q
V
A
N
I
Site 11
S244
A
K
D
R
I
P
V
S
Y
K
R
T
G
F
F
Site 12
Y245
K
D
R
I
P
V
S
Y
K
R
T
G
F
F
G
Site 13
S285
T
G
R
E
G
G
F
S
A
F
N
Q
L
K
M
Site 14
T296
Q
L
K
M
A
R
F
T
I
V
D
G
K
M
G
Site 15
S307
G
K
M
G
K
G
V
S
F
K
D
V
A
G
M
Site 16
Y327
E
V
R
E
F
V
D
Y
L
K
S
P
E
R
F
Site 17
S330
E
F
V
D
Y
L
K
S
P
E
R
F
L
Q
L
Site 18
S392
L
G
A
A
R
V
R
S
L
F
K
E
A
R
A
Site 19
S418
D
A
V
G
K
K
R
S
T
T
M
S
G
F
S
Site 20
T419
A
V
G
K
K
R
S
T
T
M
S
G
F
S
N
Site 21
T420
V
G
K
K
R
S
T
T
M
S
G
F
S
N
T
Site 22
S422
K
K
R
S
T
T
M
S
G
F
S
N
T
E
E
Site 23
T432
S
N
T
E
E
E
Q
T
L
N
Q
L
L
V
E
Site 24
S495
I
F
E
Q
H
L
K
S
L
K
L
T
Q
S
S
Site 25
T499
H
L
K
S
L
K
L
T
Q
S
S
T
F
Y
S
Site 26
S501
K
S
L
K
L
T
Q
S
S
T
F
Y
S
Q
R
Site 27
S502
S
L
K
L
T
Q
S
S
T
F
Y
S
Q
R
L
Site 28
T503
L
K
L
T
Q
S
S
T
F
Y
S
Q
R
L
A
Site 29
Y505
L
T
Q
S
S
T
F
Y
S
Q
R
L
A
E
L
Site 30
S506
T
Q
S
S
T
F
Y
S
Q
R
L
A
E
L
T
Site 31
T513
S
Q
R
L
A
E
L
T
P
G
F
S
G
A
D
Site 32
S539
A
A
R
E
G
H
T
S
V
H
T
L
N
F
E
Site 33
S560
L
A
G
T
A
K
K
S
K
I
L
S
K
E
E
Site 34
S564
A
K
K
S
K
I
L
S
K
E
E
Q
K
V
V
Site 35
S635
M
A
L
G
G
R
A
S
E
A
L
S
F
N
E
Site 36
S639
G
R
A
S
E
A
L
S
F
N
E
V
T
S
G
Site 37
T655
Q
D
D
L
R
K
V
T
R
I
A
Y
S
M
V
Site 38
Y659
R
K
V
T
R
I
A
Y
S
M
V
K
Q
F
G
Site 39
S675
A
P
G
I
G
P
I
S
F
P
E
A
Q
E
G
Site 40
S692
G
I
G
R
R
P
F
S
Q
G
L
Q
Q
M
M
Site 41
T714
V
A
K
A
Y
R
H
T
E
K
V
L
Q
D
N
Site 42
T781
G
E
E
E
T
E
E
T
Q
Q
P
P
L
G
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation