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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BAIAP2
Full Name:
Brain-specific angiogenesis inhibitor 1-associated protein 2
Alias:
BAI1-associated protein 2; BAIP2; BAP2; Fas ligand-associated factor 3; Insulin receptor substrate p53; Insulin receptor substrate p53/p58; Insulin receptor substrate protein of 53 kDa
Type:
Actin binding protein
Mass (Da):
60868
Number AA:
552
UniProt ID:
Q9UQB8
International Prot ID:
IPI00180292
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0019898
GO:0030175
Uniprot
OncoNet
Molecular Function:
GO:0017124
GO:0008093
GO:0008022
PhosphoSite+
KinaseNET
Biological Process:
GO:0007409
GO:0046847
GO:0008286
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
S
L
S
R
S
E
E
M
H
R
L
T
Site 2
T13
S
E
E
M
H
R
L
T
E
N
V
Y
K
T
I
Site 3
Y17
H
R
L
T
E
N
V
Y
K
T
I
M
E
Q
F
Site 4
S64
V
K
M
G
E
L
A
S
E
S
Q
G
S
K
E
Site 5
S66
M
G
E
L
A
S
E
S
Q
G
S
K
E
L
G
Site 6
S69
L
A
S
E
S
Q
G
S
K
E
L
G
D
V
L
Site 7
S96
Q
L
E
E
M
L
K
S
F
H
N
E
L
L
T
Site 8
S113
E
Q
K
V
E
L
D
S
R
Y
L
S
A
A
L
Site 9
Y115
K
V
E
L
D
S
R
Y
L
S
A
A
L
K
K
Site 10
S117
E
L
D
S
R
Y
L
S
A
A
L
K
K
Y
Q
Site 11
Y123
L
S
A
A
L
K
K
Y
Q
T
E
Q
R
S
K
Site 12
T125
A
A
L
K
K
Y
Q
T
E
Q
R
S
K
G
D
Site 13
S148
L
K
K
L
R
K
K
S
Q
G
S
K
N
P
Q
Site 14
Y157
G
S
K
N
P
Q
K
Y
S
D
K
E
L
Q
Y
Site 15
S158
S
K
N
P
Q
K
Y
S
D
K
E
L
Q
Y
I
Site 16
Y164
Y
S
D
K
E
L
Q
Y
I
D
A
I
S
N
K
Site 17
S169
L
Q
Y
I
D
A
I
S
N
K
Q
G
E
L
E
Site 18
Y178
K
Q
G
E
L
E
N
Y
V
S
D
G
Y
K
T
Site 19
S180
G
E
L
E
N
Y
V
S
D
G
Y
K
T
A
L
Site 20
Y183
E
N
Y
V
S
D
G
Y
K
T
A
L
T
E
E
Site 21
T188
D
G
Y
K
T
A
L
T
E
E
R
R
R
F
C
Site 22
S234
Q
Q
A
C
A
D
P
S
K
I
P
E
R
A
V
Site 23
S249
Q
L
M
Q
Q
V
A
S
N
G
A
T
L
P
S
Site 24
T253
Q
V
A
S
N
G
A
T
L
P
S
A
L
S
A
Site 25
S256
S
N
G
A
T
L
P
S
A
L
S
A
S
K
S
Site 26
S259
A
T
L
P
S
A
L
S
A
S
K
S
N
L
V
Site 27
S261
L
P
S
A
L
S
A
S
K
S
N
L
V
I
S
Site 28
S263
S
A
L
S
A
S
K
S
N
L
V
I
S
D
P
Site 29
S268
S
K
S
N
L
V
I
S
D
P
I
P
G
A
K
Site 30
S291
A
P
F
V
G
R
M
S
A
Q
E
S
T
P
I
Site 31
S295
G
R
M
S
A
Q
E
S
T
P
I
M
N
G
V
Site 32
T296
R
M
S
A
Q
E
S
T
P
I
M
N
G
V
T
Site 33
Y310
T
G
P
D
G
E
D
Y
S
P
W
A
D
R
K
Site 34
S311
G
P
D
G
E
D
Y
S
P
W
A
D
R
K
A
Site 35
S323
R
K
A
A
Q
P
K
S
L
S
P
P
Q
S
Q
Site 36
S325
A
A
Q
P
K
S
L
S
P
P
Q
S
Q
S
K
Site 37
S329
K
S
L
S
P
P
Q
S
Q
S
K
L
S
D
S
Site 38
S331
L
S
P
P
Q
S
Q
S
K
L
S
D
S
Y
S
Site 39
S334
P
Q
S
Q
S
K
L
S
D
S
Y
S
N
T
L
Site 40
S336
S
Q
S
K
L
S
D
S
Y
S
N
T
L
P
V
Site 41
Y337
Q
S
K
L
S
D
S
Y
S
N
T
L
P
V
R
Site 42
S338
S
K
L
S
D
S
Y
S
N
T
L
P
V
R
K
Site 43
T340
L
S
D
S
Y
S
N
T
L
P
V
R
K
S
V
Site 44
S346
N
T
L
P
V
R
K
S
V
T
P
K
N
S
Y
Site 45
T348
L
P
V
R
K
S
V
T
P
K
N
S
Y
A
T
Site 46
Y353
S
V
T
P
K
N
S
Y
A
T
T
E
N
K
T
Site 47
T356
P
K
N
S
Y
A
T
T
E
N
K
T
L
P
R
Site 48
T360
Y
A
T
T
E
N
K
T
L
P
R
S
S
S
M
Site 49
S364
E
N
K
T
L
P
R
S
S
S
M
A
A
G
L
Site 50
S365
N
K
T
L
P
R
S
S
S
M
A
A
G
L
E
Site 51
S366
K
T
L
P
R
S
S
S
M
A
A
G
L
E
R
Site 52
S391
S
H
A
A
G
D
N
S
T
L
L
S
F
K
E
Site 53
T392
H
A
A
G
D
N
S
T
L
L
S
F
K
E
G
Site 54
S395
G
D
N
S
T
L
L
S
F
K
E
G
D
L
I
Site 55
Y415
E
A
R
D
G
W
H
Y
G
E
S
E
K
T
K
Site 56
Y431
R
G
W
F
P
F
S
Y
T
R
V
L
D
S
D
Site 57
S437
S
Y
T
R
V
L
D
S
D
G
S
D
R
L
H
Site 58
S440
R
V
L
D
S
D
G
S
D
R
L
H
M
S
L
Site 59
S446
G
S
D
R
L
H
M
S
L
Q
Q
G
K
S
S
Site 60
S452
M
S
L
Q
Q
G
K
S
S
S
T
G
N
L
L
Site 61
S453
S
L
Q
Q
G
K
S
S
S
T
G
N
L
L
D
Site 62
S454
L
Q
Q
G
K
S
S
S
T
G
N
L
L
D
K
Site 63
T455
Q
Q
G
K
S
S
S
T
G
N
L
L
D
K
D
Site 64
S475
P
P
D
Y
G
A
A
S
R
A
F
P
A
Q
T
Site 65
T482
S
R
A
F
P
A
Q
T
A
S
G
F
K
Q
R
Site 66
S484
A
F
P
A
Q
T
A
S
G
F
K
Q
R
P
Y
Site 67
Y491
S
G
F
K
Q
R
P
Y
S
V
A
V
P
A
F
Site 68
S492
G
F
K
Q
R
P
Y
S
V
A
V
P
A
F
S
Site 69
S499
S
V
A
V
P
A
F
S
Q
G
L
D
D
Y
G
Site 70
Y505
F
S
Q
G
L
D
D
Y
G
A
R
S
M
S
R
Site 71
S509
L
D
D
Y
G
A
R
S
M
S
R
N
P
F
A
Site 72
S511
D
Y
G
A
R
S
M
S
R
N
P
F
A
H
V
Site 73
T523
A
H
V
Q
L
K
P
T
V
T
N
D
R
C
D
Site 74
T525
V
Q
L
K
P
T
V
T
N
D
R
C
D
L
S
Site 75
S532
T
N
D
R
C
D
L
S
A
Q
G
P
E
G
R
Site 76
S545
G
R
E
H
G
D
G
S
A
R
T
L
A
G
R
Site 77
T548
H
G
D
G
S
A
R
T
L
A
G
R
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation