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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ERVK6
Full Name:
HERV-K_19q12 provirus ancestral Pol protein
Alias:
HERV-K(C19) Pol protein
Type:
Mass (Da):
108106
Number AA:
959
UniProt ID:
Q9WJR5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
K
K
R
R
N
R
V
S
F
L
G
A
A
T
V
Site 2
T27
P
P
K
P
I
P
L
T
W
K
T
E
K
P
V
Site 3
S65
E
K
G
H
I
E
P
S
F
S
P
W
N
S
P
Site 4
S67
G
H
I
E
P
S
F
S
P
W
N
S
P
V
F
Site 5
S71
P
S
F
S
P
W
N
S
P
V
F
V
I
Q
K
Site 6
T87
S
G
K
W
R
M
L
T
D
L
R
A
V
N
A
Site 7
S111
P
L
Q
P
G
L
P
S
L
A
M
I
P
K
D
Site 8
T177
N
S
P
T
I
C
Q
T
F
V
G
R
A
L
Q
Site 9
Y194
R
E
K
F
S
D
C
Y
I
I
H
Y
I
D
D
Site 10
Y216
K
D
K
L
I
D
C
Y
T
F
L
Q
A
E
V
Site 11
T239
S
D
K
I
Q
T
S
T
P
F
H
Y
L
E
M
Site 12
Y243
Q
T
S
T
P
F
H
Y
L
E
M
Q
I
E
N
Site 13
T264
K
I
E
I
R
K
D
T
L
K
T
L
N
D
F
Site 14
T267
I
R
K
D
T
L
K
T
L
N
D
F
Q
K
L
Site 15
T284
D
I
N
W
I
R
P
T
L
G
I
P
T
Y
A
Site 16
S297
Y
A
M
S
N
L
F
S
I
L
R
G
D
S
D
Site 17
S303
F
S
I
L
R
G
D
S
D
L
N
S
K
R
M
Site 18
S307
R
G
D
S
D
L
N
S
K
R
M
L
T
P
E
Site 19
T312
L
N
S
K
R
M
L
T
P
E
A
T
K
E
I
Site 20
S365
N
T
D
L
V
E
W
S
F
L
P
H
S
T
V
Site 21
S370
E
W
S
F
L
P
H
S
T
V
K
T
F
T
L
Site 22
T374
L
P
H
S
T
V
K
T
F
T
L
Y
L
D
Q
Site 23
Y438
V
G
I
I
D
N
H
Y
P
K
T
K
I
F
Q
Site 24
T468
E
P
L
E
N
A
L
T
V
F
T
D
G
S
S
Site 25
S474
L
T
V
F
T
D
G
S
S
N
G
K
A
A
Y
Site 26
Y481
S
S
N
G
K
A
A
Y
T
G
P
K
E
R
V
Site 27
T491
P
K
E
R
V
I
K
T
Q
Y
Q
S
A
Q
R
Site 28
Y493
E
R
V
I
K
T
Q
Y
Q
S
A
Q
R
A
E
Site 29
Y523
N
I
I
S
D
S
A
Y
V
V
Q
A
T
R
D
Site 30
S539
E
T
A
L
I
K
Y
S
M
D
D
Q
L
N
Q
Site 31
T554
L
F
N
L
L
Q
Q
T
V
R
K
R
N
F
P
Site 32
Y563
R
K
R
N
F
P
F
Y
I
T
H
I
R
A
H
Site 33
T571
I
T
H
I
R
A
H
T
N
L
P
G
P
L
T
Site 34
T578
T
N
L
P
G
P
L
T
K
A
N
E
Q
A
D
Site 35
T658
A
L
W
Q
M
D
V
T
H
V
S
S
F
G
R
Site 36
S661
Q
M
D
V
T
H
V
S
S
F
G
R
L
S
Y
Site 37
Y668
S
S
F
G
R
L
S
Y
I
H
V
T
V
D
T
Site 38
T672
R
L
S
Y
I
H
V
T
V
D
T
Y
S
H
F
Site 39
S691
C
Q
T
G
E
S
T
S
H
V
K
K
H
L
L
Site 40
T712
G
V
P
E
K
I
K
T
D
N
G
P
G
Y
C
Site 41
Y718
K
T
D
N
G
P
G
Y
C
S
K
A
F
Q
K
Site 42
Y740
S
H
T
T
G
I
P
Y
N
S
Q
G
Q
A
I
Site 43
T757
R
T
N
R
T
L
K
T
Q
L
V
K
Q
K
E
Site 44
S768
K
Q
K
E
G
G
D
S
K
E
C
T
T
P
Q
Site 45
T772
G
G
D
S
K
E
C
T
T
P
Q
M
Q
L
N
Site 46
T773
G
D
S
K
E
C
T
T
P
Q
M
Q
L
N
L
Site 47
T795
L
N
I
Y
R
N
Q
T
T
T
S
A
E
Q
H
Site 48
T797
I
Y
R
N
Q
T
T
T
S
A
E
Q
H
L
T
Site 49
T804
T
S
A
E
Q
H
L
T
G
K
K
N
S
P
H
Site 50
S809
H
L
T
G
K
K
N
S
P
H
E
G
K
L
I
Site 51
S842
G
R
G
F
A
C
V
S
P
G
E
N
Q
L
P
Site 52
Y860
P
T
R
H
L
K
F
Y
N
E
P
I
G
D
A
Site 53
S870
P
I
G
D
A
K
K
S
T
S
A
E
T
E
T
Site 54
T875
K
K
S
T
S
A
E
T
E
T
P
Q
S
S
T
Site 55
T877
S
T
S
A
E
T
E
T
P
Q
S
S
T
V
D
Site 56
S880
A
E
T
E
T
P
Q
S
S
T
V
D
S
Q
D
Site 57
S881
E
T
E
T
P
Q
S
S
T
V
D
S
Q
D
E
Site 58
S885
P
Q
S
S
T
V
D
S
Q
D
E
Q
N
G
D
Site 59
T896
Q
N
G
D
V
R
R
T
D
E
V
A
I
H
Q
Site 60
S920
T
K
E
A
D
A
V
S
Y
K
I
S
R
E
H
Site 61
S924
D
A
V
S
Y
K
I
S
R
E
H
K
G
D
T
Site 62
T931
S
R
E
H
K
G
D
T
N
P
R
E
Y
A
A
Site 63
Y936
G
D
T
N
P
R
E
Y
A
A
C
G
L
D
D
Site 64
S950
D
C
I
N
G
G
K
S
P
Y
A
C
R
S
S
Site 65
Y952
I
N
G
G
K
S
P
Y
A
C
R
S
S
C
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation