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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DMTF1
Full Name:
Alias:
Cyclin-D-interacting Myb-like protein 1
Type:
Mass (Da):
84471
Number AA:
760
UniProt ID:
Q9Y222
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
S
T
V
E
E
D
S
D
T
V
T
V
E
T
Site 2
T10
T
V
E
E
D
S
D
T
V
T
V
E
T
V
N
Site 3
T12
E
E
D
S
D
T
V
T
V
E
T
V
N
S
V
Site 4
T22
T
V
N
S
V
T
L
T
Q
D
T
E
G
N
L
Site 5
S43
N
E
A
D
E
I
D
S
E
D
S
I
E
P
P
Site 6
S46
D
E
I
D
S
E
D
S
I
E
P
P
H
K
R
Site 7
S57
P
H
K
R
L
C
L
S
S
E
D
D
Q
S
I
Site 8
S58
H
K
R
L
C
L
S
S
E
D
D
Q
S
I
D
Site 9
S63
L
S
S
E
D
D
Q
S
I
D
D
S
T
P
C
Site 10
S67
D
D
Q
S
I
D
D
S
T
P
C
I
S
V
V
Site 11
S79
S
V
V
A
L
P
L
S
E
N
D
Q
S
F
E
Site 12
S84
P
L
S
E
N
D
Q
S
F
E
V
T
M
T
A
Site 13
T88
N
D
Q
S
F
E
V
T
M
T
A
T
T
E
V
Site 14
T90
Q
S
F
E
V
T
M
T
A
T
T
E
V
A
D
Site 15
T104
D
D
E
V
T
E
G
T
V
T
Q
I
Q
I
L
Site 16
T106
E
V
T
E
G
T
V
T
Q
I
Q
I
L
Q
N
Site 17
S120
N
E
Q
L
D
E
I
S
P
L
G
N
E
E
V
Site 18
S131
N
E
E
V
S
A
V
S
Q
A
W
F
T
T
K
Site 19
S143
T
T
K
E
D
K
D
S
L
T
N
K
G
H
K
Site 20
T145
K
E
D
K
D
S
L
T
N
K
G
H
K
W
K
Site 21
Y171
L
M
N
N
I
E
R
Y
L
K
A
R
G
I
K
Site 22
T181
A
R
G
I
K
D
A
T
E
I
I
F
E
M
S
Site 23
Y196
K
D
E
R
K
D
F
Y
R
T
I
A
W
G
L
Site 24
T198
E
R
K
D
F
Y
R
T
I
A
W
G
L
N
R
Site 25
Y211
N
R
P
L
F
A
V
Y
R
R
V
L
R
M
Y
Site 26
Y218
Y
R
R
V
L
R
M
Y
D
D
R
N
H
V
G
Site 27
T228
R
N
H
V
G
K
Y
T
P
E
E
I
E
K
L
Site 28
T248
K
H
G
N
D
W
A
T
I
G
A
A
L
G
R
Site 29
S258
A
A
L
G
R
S
A
S
S
V
K
D
R
C
R
Site 30
S259
A
L
G
R
S
A
S
S
V
K
D
R
C
R
L
Site 31
T301
T
E
P
G
D
I
V
T
Q
G
V
S
W
A
A
Site 32
T315
A
V
A
E
R
V
G
T
R
S
E
K
Q
C
R
Site 33
S317
A
E
R
V
G
T
R
S
E
K
Q
C
R
S
K
Site 34
Y328
C
R
S
K
W
L
N
Y
L
N
W
K
Q
S
G
Site 35
S372
D
L
L
A
E
G
W
S
S
V
R
S
P
Q
W
Site 36
S373
L
L
A
E
G
W
S
S
V
R
S
P
Q
W
L
Site 37
S376
E
G
W
S
S
V
R
S
P
Q
W
L
R
S
K
Site 38
S424
P
T
L
L
E
N
K
S
G
S
G
V
P
N
S
Site 39
S426
L
L
E
N
K
S
G
S
G
V
P
N
S
N
T
Site 40
S431
S
G
S
G
V
P
N
S
N
T
N
S
S
V
Q
Site 41
T433
S
G
V
P
N
S
N
T
N
S
S
V
Q
H
V
Site 42
S435
V
P
N
S
N
T
N
S
S
V
Q
H
V
Q
I
Site 43
S436
P
N
S
N
T
N
S
S
V
Q
H
V
Q
I
R
Site 44
T451
V
A
R
L
E
D
N
T
A
I
S
S
S
P
M
Site 45
S471
P
V
Q
I
T
H
V
S
S
A
D
S
P
A
T
Site 46
S475
T
H
V
S
S
A
D
S
P
A
T
V
D
S
E
Site 47
T478
S
S
A
D
S
P
A
T
V
D
S
E
T
I
T
Site 48
S481
D
S
P
A
T
V
D
S
E
T
I
T
L
N
S
Site 49
T483
P
A
T
V
D
S
E
T
I
T
L
N
S
G
T
Site 50
T485
T
V
D
S
E
T
I
T
L
N
S
G
T
L
Q
Site 51
S499
Q
T
F
E
I
L
P
S
F
H
L
Q
P
T
G
Site 52
T505
P
S
F
H
L
Q
P
T
G
T
P
G
T
Y
L
Site 53
T507
F
H
L
Q
P
T
G
T
P
G
T
Y
L
L
Q
Site 54
Y511
P
T
G
T
P
G
T
Y
L
L
Q
T
S
S
S
Site 55
T515
P
G
T
Y
L
L
Q
T
S
S
S
Q
G
L
P
Site 56
S516
G
T
Y
L
L
Q
T
S
S
S
Q
G
L
P
L
Site 57
S517
T
Y
L
L
Q
T
S
S
S
Q
G
L
P
L
T
Site 58
S558
P
E
H
L
L
N
T
S
D
N
V
T
V
Q
C
Site 59
T562
L
N
T
S
D
N
V
T
V
Q
C
H
T
P
R
Site 60
T581
T
V
A
T
E
D
I
T
S
S
I
S
Q
A
E
Site 61
S582
V
A
T
E
D
I
T
S
S
I
S
Q
A
E
L
Site 62
S585
E
D
I
T
S
S
I
S
Q
A
E
L
T
V
D
Site 63
T590
S
I
S
Q
A
E
L
T
V
D
S
D
I
Q
S
Site 64
S593
Q
A
E
L
T
V
D
S
D
I
Q
S
S
D
F
Site 65
S597
T
V
D
S
D
I
Q
S
S
D
F
P
E
P
P
Site 66
S598
V
D
S
D
I
Q
S
S
D
F
P
E
P
P
D
Site 67
T611
P
D
A
L
E
A
D
T
F
P
D
E
I
H
H
Site 68
T622
E
I
H
H
P
K
M
T
V
E
P
S
F
N
D
Site 69
S626
P
K
M
T
V
E
P
S
F
N
D
A
H
V
S
Site 70
S633
S
F
N
D
A
H
V
S
K
F
S
D
Q
N
S
Site 71
S636
D
A
H
V
S
K
F
S
D
Q
N
S
T
E
L
Site 72
S640
S
K
F
S
D
Q
N
S
T
E
L
M
N
S
V
Site 73
S646
N
S
T
E
L
M
N
S
V
M
V
R
T
E
E
Site 74
S656
V
R
T
E
E
E
I
S
D
T
D
L
K
Q
E
Site 75
T658
T
E
E
E
I
S
D
T
D
L
K
Q
E
E
S
Site 76
S665
T
D
L
K
Q
E
E
S
P
S
D
L
A
S
A
Site 77
S667
L
K
Q
E
E
S
P
S
D
L
A
S
A
Y
V
Site 78
S671
E
S
P
S
D
L
A
S
A
Y
V
T
E
G
L
Site 79
Y673
P
S
D
L
A
S
A
Y
V
T
E
G
L
E
S
Site 80
T675
D
L
A
S
A
Y
V
T
E
G
L
E
S
P
T
Site 81
S680
Y
V
T
E
G
L
E
S
P
T
I
E
E
Q
V
Site 82
T690
I
E
E
Q
V
D
Q
T
I
D
D
E
T
I
L
Site 83
T695
D
Q
T
I
D
D
E
T
I
L
I
V
P
S
P
Site 84
S709
P
H
G
F
I
Q
A
S
D
V
I
D
T
E
S
Site 85
S735
L
Q
H
H
Q
E
E
S
N
I
I
G
S
S
L
Site 86
S740
E
E
S
N
I
I
G
S
S
L
G
S
P
V
S
Site 87
S741
E
S
N
I
I
G
S
S
L
G
S
P
V
S
E
Site 88
S744
I
I
G
S
S
L
G
S
P
V
S
E
D
S
K
Site 89
S747
S
S
L
G
S
P
V
S
E
D
S
K
D
V
E
Site 90
S750
G
S
P
V
S
E
D
S
K
D
V
E
D
L
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation