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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRAF3IP3
Full Name:
TRAF3-interacting JNK-activating modulator
Alias:
T3JAM; TRAF3 interacting Jun N terminal kinase (JNK) activating modulator; TRAF3 interacting protein 3; TRAF3-interacting Jun N-terminal kinase (JNK)-activating modulator; TRAF3-interacting protein 3
Type:
Adaptor/scaffold
Mass (Da):
63626
Number AA:
551
UniProt ID:
Q9Y228
International Prot ID:
IPI00719170
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
I
S
P
D
P
R
P
S
P
Site 2
S9
I
S
P
D
P
R
P
S
P
G
L
A
R
W
A
Site 3
Y19
L
A
R
W
A
E
S
Y
E
A
K
C
E
R
R
Site 4
S32
R
R
Q
E
I
R
E
S
R
R
C
R
P
N
V
Site 5
T41
R
C
R
P
N
V
T
T
C
R
Q
V
G
K
T
Site 6
T48
T
C
R
Q
V
G
K
T
L
R
I
Q
Q
R
E
Site 7
S90
Q
A
R
E
Q
G
P
S
R
R
P
G
Q
V
T
Site 8
T97
S
R
R
P
G
Q
V
T
V
L
K
E
P
L
S
Site 9
S104
T
V
L
K
E
P
L
S
C
A
R
R
I
S
S
Site 10
S110
L
S
C
A
R
R
I
S
S
P
R
E
Q
V
T
Site 11
S111
S
C
A
R
R
I
S
S
P
R
E
Q
V
T
G
Site 12
T117
S
S
P
R
E
Q
V
T
G
T
S
S
E
V
F
Site 13
S120
R
E
Q
V
T
G
T
S
S
E
V
F
P
A
Q
Site 14
S132
P
A
Q
H
P
P
P
S
G
I
C
R
D
L
S
Site 15
S139
S
G
I
C
R
D
L
S
D
H
L
S
S
Q
A
Site 16
S143
R
D
L
S
D
H
L
S
S
Q
A
G
G
L
P
Site 17
S144
D
L
S
D
H
L
S
S
Q
A
G
G
L
P
P
Site 18
T154
G
G
L
P
P
Q
D
T
P
I
K
K
P
P
K
Site 19
T166
P
P
K
H
H
R
G
T
Q
T
K
A
E
G
P
Site 20
S180
P
T
I
K
N
D
A
S
Q
Q
T
N
Y
G
V
Site 21
Y185
D
A
S
Q
Q
T
N
Y
G
V
A
V
L
D
K
Site 22
S198
D
K
E
I
I
Q
L
S
D
Y
L
K
E
A
L
Site 23
Y200
E
I
I
Q
L
S
D
Y
L
K
E
A
L
Q
R
Site 24
S229
L
S
T
L
I
Q
A
S
D
S
S
W
K
G
Q
Site 25
S231
T
L
I
Q
A
S
D
S
S
W
K
G
Q
L
N
Site 26
S232
L
I
Q
A
S
D
S
S
W
K
G
Q
L
N
E
Site 27
S248
K
L
K
G
K
L
R
S
L
E
N
Q
L
Y
T
Site 28
Y254
R
S
L
E
N
Q
L
Y
T
C
T
Q
K
Y
S
Site 29
T255
S
L
E
N
Q
L
Y
T
C
T
Q
K
Y
S
P
Site 30
Y260
L
Y
T
C
T
Q
K
Y
S
P
W
G
M
K
K
Site 31
S303
N
A
E
Q
Q
L
Q
S
T
Q
R
S
L
A
L
Site 32
T304
A
E
Q
Q
L
Q
S
T
Q
R
S
L
A
L
A
Site 33
S307
Q
L
Q
S
T
Q
R
S
L
A
L
A
E
Q
K
Site 34
S320
Q
K
C
E
E
W
R
S
Q
Y
E
A
L
K
E
Site 35
Y322
C
E
E
W
R
S
Q
Y
E
A
L
K
E
D
W
Site 36
T331
A
L
K
E
D
W
R
T
L
G
T
Q
H
R
E
Site 37
T334
E
D
W
R
T
L
G
T
Q
H
R
E
L
E
S
Site 38
S341
T
Q
H
R
E
L
E
S
Q
L
H
V
L
Q
S
Site 39
S348
S
Q
L
H
V
L
Q
S
K
L
Q
G
A
D
S
Site 40
S355
S
K
L
Q
G
A
D
S
R
D
L
Q
M
N
Q
Site 41
S389
Q
G
D
R
D
L
C
S
L
D
T
Q
D
L
Q
Site 42
T392
R
D
L
C
S
L
D
T
Q
D
L
Q
D
Q
L
Site 43
S424
Q
G
L
L
Q
N
Q
S
L
Q
L
Q
E
Q
E
Site 44
T435
Q
E
Q
E
K
L
L
T
K
K
D
Q
A
L
P
Site 45
S445
D
Q
A
L
P
V
W
S
P
K
S
F
P
N
E
Site 46
S448
L
P
V
W
S
P
K
S
F
P
N
E
V
E
P
Site 47
S489
K
E
C
R
E
L
H
S
E
L
D
N
L
S
D
Site 48
S495
H
S
E
L
D
N
L
S
D
E
Y
L
S
C
L
Site 49
Y498
L
D
N
L
S
D
E
Y
L
S
C
L
R
K
L
Site 50
S500
N
L
S
D
E
Y
L
S
C
L
R
K
L
Q
H
Site 51
S515
C
R
E
E
L
N
Q
S
Q
Q
L
P
P
R
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation