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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NOD1
Full Name:
Alias:
Caspase recruitment domain-containing protein 4
Type:
Mass (Da):
107691
Number AA:
953
UniProt ID:
Q9Y239
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
E
E
Q
G
H
S
E
M
E
I
I
P
S
Site 2
S14
S
E
M
E
I
I
P
S
E
S
H
P
H
I
Q
Site 3
S25
P
H
I
Q
L
L
K
S
N
R
E
L
L
V
T
Site 4
T32
S
N
R
E
L
L
V
T
H
I
R
N
T
Q
C
Site 5
Y49
D
N
L
L
K
N
D
Y
F
S
A
E
D
A
E
Site 6
S51
L
L
K
N
D
Y
F
S
A
E
D
A
E
I
V
Site 7
S77
K
I
L
D
L
V
Q
S
K
G
E
E
V
S
E
Site 8
S117
S
P
S
L
L
T
Q
S
K
V
V
V
N
T
D
Site 9
T123
Q
S
K
V
V
V
N
T
D
P
V
S
R
Y
T
Site 10
S127
V
V
N
T
D
P
V
S
R
Y
T
Q
Q
L
R
Site 11
T130
T
D
P
V
S
R
Y
T
Q
Q
L
R
H
H
L
Site 12
S209
G
D
A
G
V
G
K
S
M
L
L
Q
R
L
Q
Site 13
S217
M
L
L
Q
R
L
Q
S
L
W
A
T
G
R
L
Site 14
T221
R
L
Q
S
L
W
A
T
G
R
L
D
A
G
V
Site 15
Y258
Q
D
L
L
F
K
H
Y
C
Y
P
E
R
D
P
Site 16
Y260
L
L
F
K
H
Y
C
Y
P
E
R
D
P
E
E
Site 17
S291
D
G
L
D
E
L
H
S
D
L
D
L
S
R
V
Site 18
S296
L
H
S
D
L
D
L
S
R
V
P
D
S
S
C
Site 19
S301
D
L
S
R
V
P
D
S
S
C
P
W
E
P
A
Site 20
S302
L
S
R
V
P
D
S
S
C
P
W
E
P
A
H
Site 21
T331
K
G
A
S
K
L
L
T
A
R
T
G
I
E
V
Site 22
T334
S
K
L
L
T
A
R
T
G
I
E
V
P
R
Q
Site 23
S353
K
V
L
L
R
G
F
S
P
S
H
L
R
A
Y
Site 24
S355
L
L
R
G
F
S
P
S
H
L
R
A
Y
A
R
Site 25
Y360
S
P
S
H
L
R
A
Y
A
R
R
M
F
P
E
Site 26
S376
A
L
Q
D
R
L
L
S
Q
L
E
A
N
P
N
Site 27
S411
F
R
A
A
F
E
G
S
P
Q
L
P
D
C
T
Site 28
S440
L
N
R
M
Q
P
S
S
L
V
Q
R
N
T
R
Site 29
T446
S
S
L
V
Q
R
N
T
R
S
P
V
E
T
L
Site 30
S448
L
V
Q
R
N
T
R
S
P
V
E
T
L
H
A
Site 31
T452
N
T
R
S
P
V
E
T
L
H
A
G
R
D
T
Site 32
S462
A
G
R
D
T
L
C
S
L
G
Q
V
A
H
R
Site 33
S474
A
H
R
G
M
E
K
S
L
F
V
F
T
Q
E
Site 34
S512
G
P
G
G
D
Q
Q
S
Y
E
F
F
H
L
T
Site 35
Y513
P
G
G
D
Q
Q
S
Y
E
F
F
H
L
T
L
Site 36
S571
P
F
Q
C
L
Q
G
S
G
P
A
R
E
D
L
Site 37
S634
S
L
R
G
Y
L
K
S
L
P
R
V
Q
V
E
Site 38
S642
L
P
R
V
Q
V
E
S
F
N
Q
V
Q
A
M
Site 39
Y660
I
W
M
L
R
C
I
Y
E
T
Q
S
Q
K
V
Site 40
T662
M
L
R
C
I
Y
E
T
Q
S
Q
K
V
G
Q
Site 41
S664
R
C
I
Y
E
T
Q
S
Q
K
V
G
Q
L
A
Site 42
Y718
D
N
N
N
L
N
D
Y
G
V
R
E
L
Q
P
Site 43
S728
R
E
L
Q
P
C
F
S
R
L
T
V
L
R
L
Site 44
S749
D
G
G
V
K
V
L
S
E
E
L
T
K
Y
K
Site 45
T753
K
V
L
S
E
E
L
T
K
Y
K
I
V
T
Y
Site 46
Y755
L
S
E
E
L
T
K
Y
K
I
V
T
Y
L
G
Site 47
T777
D
V
G
A
R
Y
V
T
K
I
L
D
E
C
K
Site 48
S798
L
G
K
N
K
I
T
S
E
G
G
K
Y
L
A
Site 49
S813
L
A
V
K
N
S
K
S
I
S
E
V
G
M
W
Site 50
S815
V
K
N
S
K
S
I
S
E
V
G
M
W
G
N
Site 51
S841
E
A
L
R
N
H
P
S
L
T
T
L
S
L
A
Site 52
T843
L
R
N
H
P
S
L
T
T
L
S
L
A
S
N
Site 53
T844
R
N
H
P
S
L
T
T
L
S
L
A
S
N
G
Site 54
S853
S
L
A
S
N
G
I
S
T
E
G
G
K
S
L
Site 55
S859
I
S
T
E
G
G
K
S
L
A
R
A
L
Q
Q
Site 56
S869
R
A
L
Q
Q
N
T
S
L
E
I
L
W
L
T
Site 57
S922
Q
L
A
D
A
L
Q
S
N
T
G
I
T
E
I
Site 58
Y944
K
P
E
E
A
K
V
Y
E
D
E
K
R
I
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation