PhosphoNET

           
Protein Info 
   
Short Name:  LZTS1
Full Name:  Leucine zipper putative tumor suppressor 1
Alias:  F37; F37/esophageal cancer-related gene-coding leucine-zipper motif; Fez1; FEZ1; Leucine zipper, putative tumor suppressor 1
Type:  Transcription factor
Mass (Da):  66482
Number AA:  595
UniProt ID:  Q9Y250
International Prot ID:  IPI00026058
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005794  GO:0030054  GO:0043197 Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0003700   PhosphoSite+ KinaseNET
Biological Process:  GO:0007049  GO:0006355  GO:0006350 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S9GSVSSLISGHSFHSK
Site 2S12SSLISGHSFHSKHCR
Site 3S15ISGHSFHSKHCRASQ
Site 4S21HSKHCRASQYKLRKS
Site 5Y23KHCRASQYKLRKSSH
Site 6S28SQYKLRKSSHLKKLN
Site 7S29QYKLRKSSHLKKLNR
Site 8S38LKKLNRYSDGLLRFG
Site 9S47GLLRFGFSQDSGHGK
Site 10S50RFGFSQDSGHGKSSS
Site 11S55QDSGHGKSSSKMGKS
Site 12S57SGHGKSSSKMGKSED
Site 13S62SSSKMGKSEDFFYIK
Site 14Y67GKSEDFFYIKVSQKA
Site 15S71DFFYIKVSQKARGSH
Site 16S77VSQKARGSHHPDYTA
Site 17Y82RGSHHPDYTALSSGD
Site 18T83GSHHPDYTALSSGDL
Site 19S86HPDYTALSSGDLGGQ
Site 20S87PDYTALSSGDLGGQA
Site 21S101AGVDFDPSTPPKLMP
Site 22T102GVDFDPSTPPKLMPF
Site 23S110PPKLMPFSNQLEMGS
Site 24T125EKGAVRPTAFKPVLP
Site 25S140RSGAILHSSPESASH
Site 26S141SGAILHSSPESASHQ
Site 27S144ILHSSPESASHQLHP
Site 28S146HSSPESASHQLHPAP
Site 29S168ELKPGLCSGALSDSG
Site 30S172GLCSGALSDSGRNSM
Site 31S174CSGALSDSGRNSMSS
Site 32S178LSDSGRNSMSSLPTH
Site 33S180DSGRNSMSSLPTHST
Site 34S181SGRNSMSSLPTHSTS
Site 35T184NSMSSLPTHSTSSSY
Site 36S186MSSLPTHSTSSSYQL
Site 37T187SSLPTHSTSSSYQLD
Site 38S188SLPTHSTSSSYQLDP
Site 39S189LPTHSTSSSYQLDPL
Site 40S190PTHSTSSSYQLDPLV
Site 41T198YQLDPLVTPVGPTSR
Site 42S204VTPVGPTSRFGGSAH
Site 43S209PTSRFGGSAHNITQG
Site 44T214GGSAHNITQGIVLQD
Site 45S222QGIVLQDSNMMSLKA
Site 46S226LQDSNMMSLKALSFS
Site 47S231MMSLKALSFSDGGSK
Site 48S233SLKALSFSDGGSKLG
Site 49S237LSFSDGGSKLGHSNK
Site 50S242GGSKLGHSNKADKGP
Site 51S250NKADKGPSCVRSPIS
Site 52S254KGPSCVRSPISTDEC
Site 53S257SCVRSPISTDECSIQ
Site 54T258CVRSPISTDECSIQE
Site 55S262PISTDECSIQELEQK
Site 56S283ALQKLQRSFEEKELA
Site 57S292EEKELASSLAYEERP
Site 58Y295ELASSLAYEERPRRC
Site 59S321GNKLKQASQKSQRAQ
Site 60S324LKQASQKSQRAQQVL
Site 61S351QLRQELESLMKEQDL
Site 62S365LLETKLRSYEREKTS
Site 63Y366LETKLRSYEREKTSF
Site 64T371RSYEREKTSFGPALE
Site 65S372SYEREKTSFGPALEE
Site 66S388QWEVCQKSGEISLLK
Site 67S392CQKSGEISLLKQQLK
Site 68S401LKQQLKESQTEVNAK
Site 69T433LEGLELRTQDLEGAL
Site 70T492ARDMGPPTFPEDVPA
Site 71Y550QKQLQQSYVAMYQRN
Site 72Y554QQSYVAMYQRNQRLE
Site 73S572QQLARGDSAGEPLEV
Site 74Y588LEGADIPYEDIIATE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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