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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CHKB
Full Name:
Alias:
Choline kinase beta;Choline kinase-like protein;Ethanolamine kinase;Ethanolamine kinase beta;choline/ethanolamine kinase beta
Type:
Mass (Da):
45271
Number AA:
395
UniProt ID:
Q9Y259
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S26
A
K
D
G
L
Q
Q
S
K
C
P
D
T
T
P
Site 2
T31
Q
Q
S
K
C
P
D
T
T
P
K
R
R
R
A
Site 3
T32
Q
S
K
C
P
D
T
T
P
K
R
R
R
A
S
Site 4
S39
T
P
K
R
R
R
A
S
S
L
S
R
D
A
E
Site 5
S40
P
K
R
R
R
A
S
S
L
S
R
D
A
E
R
Site 6
S42
R
R
R
A
S
S
L
S
R
D
A
E
R
R
A
Site 7
Y50
R
D
A
E
R
R
A
Y
Q
W
C
R
E
Y
L
Site 8
Y72
Q
P
E
E
L
R
V
Y
P
V
S
G
G
L
S
Site 9
S75
E
L
R
V
Y
P
V
S
G
G
L
S
N
L
L
Site 10
S79
Y
P
V
S
G
G
L
S
N
L
L
F
R
C
S
Site 11
S86
S
N
L
L
F
R
C
S
L
P
D
H
L
P
S
Site 12
S93
S
L
P
D
H
L
P
S
V
G
E
E
P
R
E
Site 13
Y136
R
S
L
G
P
Q
L
Y
G
V
F
P
E
G
R
Site 14
Y147
P
E
G
R
L
E
Q
Y
I
P
S
R
P
L
K
Site 15
T191
E
P
H
W
L
F
G
T
M
E
R
Y
L
K
Q
Site 16
Y195
L
F
G
T
M
E
R
Y
L
K
Q
I
Q
D
L
Site 17
T205
Q
I
Q
D
L
P
P
T
G
L
P
E
M
N
L
Site 18
Y216
E
M
N
L
L
E
M
Y
S
L
K
D
E
M
G
Site 19
S217
M
N
L
L
E
M
Y
S
L
K
D
E
M
G
N
Site 20
S231
N
L
R
K
L
L
E
S
T
P
S
P
V
V
F
Site 21
S234
K
L
L
E
S
T
P
S
P
V
V
F
C
H
N
Site 22
S252
E
G
N
I
L
L
L
S
E
P
E
N
A
D
S
Site 23
S259
S
E
P
E
N
A
D
S
L
M
L
V
D
F
E
Site 24
Y267
L
M
L
V
D
F
E
Y
S
S
Y
N
Y
R
G
Site 25
Y270
V
D
F
E
Y
S
S
Y
N
Y
R
G
F
D
I
Site 26
Y272
F
E
Y
S
S
Y
N
Y
R
G
F
D
I
G
N
Site 27
Y296
T
H
E
E
W
P
F
Y
K
A
R
P
T
D
Y
Site 28
T301
P
F
Y
K
A
R
P
T
D
Y
P
T
Q
E
Q
Site 29
Y303
Y
K
A
R
P
T
D
Y
P
T
Q
E
Q
Q
L
Site 30
T305
A
R
P
T
D
Y
P
T
Q
E
Q
Q
L
H
F
Site 31
Y316
Q
L
H
F
I
R
H
Y
L
A
E
A
K
K
G
Site 32
S327
A
K
K
G
E
T
L
S
Q
E
E
Q
R
K
L
Site 33
Y370
M
S
T
I
E
F
G
Y
L
D
Y
A
Q
S
R
Site 34
Y373
I
E
F
G
Y
L
D
Y
A
Q
S
R
F
Q
F
Site 35
Y381
A
Q
S
R
F
Q
F
Y
F
Q
Q
K
G
Q
L
Site 36
T389
F
Q
Q
K
G
Q
L
T
S
V
H
S
S
S
_
Site 37
S390
Q
Q
K
G
Q
L
T
S
V
H
S
S
S
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation