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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PLAA
Full Name:
Phospholipase A-2-activating protein
Alias:
DOA1; FLJ11281; FLJ12699; phospholipase A-2-activating; phospholipase A2-activating protein; PLA2P; PLAP
Type:
Activator protein
Mass (Da):
87160
Number AA:
795
UniProt ID:
Q9Y263
International Prot ID:
IPI00218465
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0016005
GO:0008047
GO:0016004
PhosphoSite+
KinaseNET
Biological Process:
GO:0006644
GO:0007165
GO:0006644
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
G
A
T
R
Y
R
L
S
C
S
L
R
G
H
E
Site 2
S13
T
R
Y
R
L
S
C
S
L
R
G
H
E
L
D
Site 3
S36
Y
P
P
G
A
F
V
S
V
S
R
D
R
T
T
Site 4
S38
P
G
A
F
V
S
V
S
R
D
R
T
T
R
L
Site 5
T42
V
S
V
S
R
D
R
T
T
R
L
W
A
P
D
Site 6
T43
S
V
S
R
D
R
T
T
R
L
W
A
P
D
S
Site 7
S50
T
R
L
W
A
P
D
S
P
N
R
S
F
T
E
Site 8
S54
A
P
D
S
P
N
R
S
F
T
E
M
H
C
M
Site 9
T56
D
S
P
N
R
S
F
T
E
M
H
C
M
S
G
Site 10
Y106
L
D
S
P
M
P
L
Y
I
L
K
G
H
K
N
Site 11
T114
I
L
K
G
H
K
N
T
V
C
S
L
S
S
G
Site 12
S117
G
H
K
N
T
V
C
S
L
S
S
G
K
F
G
Site 13
S119
K
N
T
V
C
S
L
S
S
G
K
F
G
T
L
Site 14
T125
L
S
S
G
K
F
G
T
L
L
S
G
S
W
D
Site 15
S128
G
K
F
G
T
L
L
S
G
S
W
D
T
T
A
Site 16
T134
L
S
G
S
W
D
T
T
A
K
V
W
L
N
D
Site 17
T174
L
T
G
S
A
D
K
T
V
K
L
W
K
A
G
Site 18
T186
K
A
G
R
C
E
R
T
F
S
G
H
E
D
C
Site 19
S188
G
R
C
E
R
T
F
S
G
H
E
D
C
V
R
Site 20
T220
S
I
R
R
W
Q
I
T
G
E
C
L
E
V
Y
Site 21
Y227
T
G
E
C
L
E
V
Y
Y
G
H
T
N
Y
I
Site 22
Y235
Y
G
H
T
N
Y
I
Y
S
I
S
V
F
P
N
Site 23
T248
P
N
C
R
D
F
V
T
T
A
E
D
R
S
L
Site 24
T249
N
C
R
D
F
V
T
T
A
E
D
R
S
L
R
Site 25
S254
V
T
T
A
E
D
R
S
L
R
I
W
K
H
G
Site 26
T266
K
H
G
E
C
A
Q
T
I
R
L
P
A
Q
S
Site 27
T298
D
G
I
I
R
V
F
T
E
S
E
D
R
T
A
Site 28
S300
I
I
R
V
F
T
E
S
E
D
R
T
A
S
A
Site 29
T304
F
T
E
S
E
D
R
T
A
S
A
E
E
I
K
Site 30
S306
E
S
E
D
R
T
A
S
A
E
E
I
K
A
F
Site 31
S318
K
A
F
E
K
E
L
S
H
A
T
I
D
S
K
Site 32
S324
L
S
H
A
T
I
D
S
K
T
G
D
L
G
D
Site 33
T326
H
A
T
I
D
S
K
T
G
D
L
G
D
I
N
Site 34
Y365
D
G
E
K
V
E
A
Y
Q
W
S
V
S
E
G
Site 35
S391
S
G
A
N
Q
Q
T
S
G
K
V
L
Y
E
G
Site 36
Y396
Q
T
S
G
K
V
L
Y
E
G
K
E
F
D
Y
Site 37
Y403
Y
E
G
K
E
F
D
Y
V
F
S
I
D
V
N
Site 38
S406
K
E
F
D
Y
V
F
S
I
D
V
N
E
G
G
Site 39
S415
D
V
N
E
G
G
P
S
Y
K
L
P
Y
N
T
Site 40
Y416
V
N
E
G
G
P
S
Y
K
L
P
Y
N
T
S
Site 41
S423
Y
K
L
P
Y
N
T
S
D
D
P
W
L
T
A
Site 42
T429
T
S
D
D
P
W
L
T
A
Y
N
F
L
Q
K
Site 43
Y431
D
D
P
W
L
T
A
Y
N
F
L
Q
K
N
D
Site 44
S466
M
L
G
L
G
N
P
S
F
S
D
P
F
T
G
Site 45
S468
G
L
G
N
P
S
F
S
D
P
F
T
G
G
G
Site 46
T472
P
S
F
S
D
P
F
T
G
G
G
R
Y
V
P
Site 47
Y477
P
F
T
G
G
G
R
Y
V
P
G
S
S
G
S
Site 48
S481
G
G
R
Y
V
P
G
S
S
G
S
S
N
T
L
Site 49
S482
G
R
Y
V
P
G
S
S
G
S
S
N
T
L
P
Site 50
S485
V
P
G
S
S
G
S
S
N
T
L
P
T
A
D
Site 51
T490
G
S
S
N
T
L
P
T
A
D
P
F
T
G
A
Site 52
T495
L
P
T
A
D
P
F
T
G
A
G
R
Y
V
P
Site 53
Y500
P
F
T
G
A
G
R
Y
V
P
G
S
A
S
M
Site 54
S504
A
G
R
Y
V
P
G
S
A
S
M
G
T
T
M
Site 55
S506
R
Y
V
P
G
S
A
S
M
G
T
T
M
A
G
Site 56
T509
P
G
S
A
S
M
G
T
T
M
A
G
V
D
P
Site 57
T510
G
S
A
S
M
G
T
T
M
A
G
V
D
P
F
Site 58
T518
M
A
G
V
D
P
F
T
G
N
S
A
Y
R
S
Site 59
S521
V
D
P
F
T
G
N
S
A
Y
R
S
A
A
S
Site 60
Y523
P
F
T
G
N
S
A
Y
R
S
A
A
S
K
T
Site 61
S525
T
G
N
S
A
Y
R
S
A
A
S
K
T
M
N
Site 62
Y534
A
S
K
T
M
N
I
Y
F
P
K
K
E
A
V
Site 63
T561
K
L
K
E
L
N
G
T
A
P
E
E
K
K
L
Site 64
T569
A
P
E
E
K
K
L
T
E
D
D
L
I
L
L
Site 65
S587
L
S
L
I
C
N
S
S
S
E
K
P
T
V
Q
Site 66
S588
S
L
I
C
N
S
S
S
E
K
P
T
V
Q
Q
Site 67
T592
N
S
S
S
E
K
P
T
V
Q
Q
L
Q
I
L
Site 68
S678
A
G
Q
K
L
M
M
S
Q
R
E
S
L
M
S
Site 69
S682
L
M
M
S
Q
R
E
S
L
M
S
H
A
I
E
Site 70
S685
S
Q
R
E
S
L
M
S
H
A
I
E
L
K
S
Site 71
S692
S
H
A
I
E
L
K
S
G
S
N
K
N
I
H
Site 72
S694
A
I
E
L
K
S
G
S
N
K
N
I
H
I
A
Site 73
S757
G
T
L
I
S
D
D
S
N
A
V
Q
L
A
K
Site 74
S770
A
K
S
L
G
V
D
S
Q
I
K
K
Y
S
S
Site 75
Y775
V
D
S
Q
I
K
K
Y
S
S
V
S
E
P
A
Site 76
S776
D
S
Q
I
K
K
Y
S
S
V
S
E
P
A
K
Site 77
S777
S
Q
I
K
K
Y
S
S
V
S
E
P
A
K
V
Site 78
S779
I
K
K
Y
S
S
V
S
E
P
A
K
V
S
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation