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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RUVBL1
Full Name:
RuvB-like 1
Alias:
49 kDa TATA box-binding protein-interacting protein
Type:
Mass (Da):
50210
Number AA:
456
UniProt ID:
Q9Y265
International Prot ID:
IPI00021187
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000123
GO:0005634
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003678
GO:0003824
PhosphoSite+
KinaseNET
Biological Process:
GO:0000003
GO:0001558
GO:0006139
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
K
I
E
E
V
K
S
T
T
K
T
Q
R
I
Site 2
T12
E
V
K
S
T
T
K
T
Q
R
I
A
S
H
S
Site 3
S17
T
K
T
Q
R
I
A
S
H
S
H
V
K
G
L
Site 4
S19
T
Q
R
I
A
S
H
S
H
V
K
G
L
G
L
Site 5
S29
K
G
L
G
L
D
E
S
G
L
A
K
Q
A
A
Site 6
S103
M
V
G
S
E
V
Y
S
T
E
I
K
K
T
E
Site 7
T104
V
G
S
E
V
Y
S
T
E
I
K
K
T
E
V
Site 8
T109
Y
S
T
E
I
K
K
T
E
V
L
M
E
N
F
Site 9
T127
I
G
L
R
I
K
E
T
K
E
V
Y
E
G
E
Site 10
T136
E
V
Y
E
G
E
V
T
E
L
T
P
C
E
T
Site 11
T139
E
G
E
V
T
E
L
T
P
C
E
T
E
N
P
Site 12
T143
T
E
L
T
P
C
E
T
E
N
P
M
G
G
Y
Site 13
T153
P
M
G
G
Y
G
K
T
I
S
H
V
I
I
G
Site 14
T163
H
V
I
I
G
L
K
T
A
K
G
T
K
Q
L
Site 15
S175
K
Q
L
K
L
D
P
S
I
F
E
S
L
Q
K
Site 16
S179
L
D
P
S
I
F
E
S
L
Q
K
E
R
V
E
Site 17
Y192
V
E
A
G
D
V
I
Y
I
E
A
N
S
G
A
Site 18
T208
K
R
Q
G
R
C
D
T
Y
A
T
E
F
D
L
Site 19
Y209
R
Q
G
R
C
D
T
Y
A
T
E
F
D
L
E
Site 20
Y220
F
D
L
E
A
E
E
Y
V
P
L
P
K
G
D
Site 21
S258
Q
G
G
Q
D
I
L
S
M
M
G
Q
L
M
K
Site 22
Y286
I
N
K
V
V
N
K
Y
I
D
Q
G
I
A
E
Site 23
T341
G
N
C
V
I
R
G
T
E
D
I
T
S
P
H
Site 24
T345
I
R
G
T
E
D
I
T
S
P
H
G
I
P
L
Site 25
S346
R
G
T
E
D
I
T
S
P
H
G
I
P
L
D
Site 26
T363
D
R
V
M
I
I
R
T
M
L
Y
T
P
Q
E
Site 27
Y366
M
I
I
R
T
M
L
Y
T
P
Q
E
M
K
Q
Site 28
T367
I
I
R
T
M
L
Y
T
P
Q
E
M
K
Q
I
Site 29
T381
I
I
K
I
R
A
Q
T
E
G
I
N
I
S
E
Site 30
S387
Q
T
E
G
I
N
I
S
E
E
A
L
N
H
L
Site 31
T401
L
G
E
I
G
T
K
T
T
L
R
Y
S
V
Q
Site 32
T402
G
E
I
G
T
K
T
T
L
R
Y
S
V
Q
L
Site 33
S406
T
K
T
T
L
R
Y
S
V
Q
L
L
T
P
A
Site 34
S424
A
K
I
N
G
K
D
S
I
E
K
E
H
V
E
Site 35
Y438
E
E
I
S
E
L
F
Y
D
A
K
S
S
A
K
Site 36
S442
E
L
F
Y
D
A
K
S
S
A
K
I
L
A
D
Site 37
Y454
L
A
D
Q
Q
D
K
Y
M
K
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation