KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZNF443
Full Name:
Zinc finger protein 443
Alias:
Krueppel-type zinc finger protein ZK1; Kruppel-type zinc finger (C2H2); ZK1; ZN443
Type:
Mass (Da):
77550
Number AA:
UniProt ID:
Q9Y2A4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006917
GO:0006355
GO:0006950
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y29
G
P
C
Q
K
N
L
Y
K
D
V
M
Q
E
T
Site 2
Y56
D
Q
N
I
E
D
Q
Y
R
Y
P
R
K
N
L
Site 3
Y58
N
I
E
D
Q
Y
R
Y
P
R
K
N
L
R
C
Site 4
T78
F
I
E
S
K
D
G
T
Q
C
G
E
T
S
S
Site 5
S85
T
Q
C
G
E
T
S
S
Q
I
Q
D
S
I
V
Site 6
S90
T
S
S
Q
I
Q
D
S
I
V
T
K
N
T
L
Site 7
S105
P
G
V
G
P
C
E
S
S
M
R
G
E
K
V
Site 8
S106
G
V
G
P
C
E
S
S
M
R
G
E
K
V
M
Site 9
Y121
G
H
S
S
L
N
C
Y
I
R
V
G
A
G
H
Site 10
Y133
A
G
H
K
P
H
E
Y
H
E
C
G
E
K
P
Site 11
T142
E
C
G
E
K
P
D
T
H
K
Q
R
G
K
A
Site 12
S151
K
Q
R
G
K
A
F
S
Y
H
N
S
F
Q
T
Site 13
Y152
Q
R
G
K
A
F
S
Y
H
N
S
F
Q
T
H
Site 14
S155
K
A
F
S
Y
H
N
S
F
Q
T
H
E
R
L
Site 15
T164
Q
T
H
E
R
L
H
T
G
K
K
P
Y
D
C
Site 16
Y169
L
H
T
G
K
K
P
Y
D
C
K
E
C
G
K
Site 17
S177
D
C
K
E
C
G
K
S
F
S
S
L
G
N
L
Site 18
S179
K
E
C
G
K
S
F
S
S
L
G
N
L
Q
R
Site 19
S180
E
C
G
K
S
F
S
S
L
G
N
L
Q
R
H
Site 20
Y197
V
Q
R
G
D
G
P
Y
K
C
K
L
C
G
K
Site 21
T218
L
L
H
M
H
E
R
T
H
T
G
E
K
P
Y
Site 22
T220
H
M
H
E
R
T
H
T
G
E
K
P
Y
E
C
Site 23
Y225
T
H
T
G
E
K
P
Y
E
C
K
Q
C
S
K
Site 24
S235
K
Q
C
S
K
A
F
S
F
Y
S
S
Y
L
R
Site 25
S238
S
K
A
F
S
F
Y
S
S
Y
L
R
H
E
R
Site 26
S239
K
A
F
S
F
Y
S
S
Y
L
R
H
E
R
T
Site 27
Y240
A
F
S
F
Y
S
S
Y
L
R
H
E
R
T
H
Site 28
T246
S
Y
L
R
H
E
R
T
H
T
G
E
K
P
Y
Site 29
T248
L
R
H
E
R
T
H
T
G
E
K
P
Y
E
C
Site 30
Y265
C
S
K
A
F
P
F
Y
S
S
Y
L
R
H
E
Site 31
S266
S
K
A
F
P
F
Y
S
S
Y
L
R
H
E
R
Site 32
Y268
A
F
P
F
Y
S
S
Y
L
R
H
E
R
T
H
Site 33
T276
L
R
H
E
R
T
H
T
G
E
K
P
Y
K
C
Site 34
S287
P
Y
K
C
K
Q
C
S
K
A
F
P
D
S
S
Site 35
S293
C
S
K
A
F
P
D
S
S
S
C
L
I
H
E
Site 36
S294
S
K
A
F
P
D
S
S
S
C
L
I
H
E
R
Site 37
S295
K
A
F
P
D
S
S
S
C
L
I
H
E
R
T
Site 38
T302
S
C
L
I
H
E
R
T
H
T
G
E
K
P
Y
Site 39
T304
L
I
H
E
R
T
H
T
G
E
K
P
Y
T
C
Site 40
Y309
T
H
T
G
E
K
P
Y
T
C
K
Q
C
G
K
Site 41
T310
H
T
G
E
K
P
Y
T
C
K
Q
C
G
K
A
Site 42
S319
K
Q
C
G
K
A
F
S
V
S
G
S
L
Q
R
Site 43
S323
K
A
F
S
V
S
G
S
L
Q
R
H
E
T
T
Site 44
T329
G
S
L
Q
R
H
E
T
T
H
S
A
E
K
P
Site 45
S332
Q
R
H
E
T
T
H
S
A
E
K
P
Y
A
C
Site 46
Y337
T
H
S
A
E
K
P
Y
A
C
Q
Q
C
G
K
Site 47
T360
Q
R
H
M
I
R
H
T
G
N
G
P
H
K
C
Site 48
S378
G
K
G
F
D
C
P
S
S
L
Q
S
H
E
R
Site 49
S379
K
G
F
D
C
P
S
S
L
Q
S
H
E
R
T
Site 50
S382
D
C
P
S
S
L
Q
S
H
E
R
T
H
T
G
Site 51
T386
S
L
Q
S
H
E
R
T
H
T
G
E
K
P
Y
Site 52
T388
Q
S
H
E
R
T
H
T
G
E
K
P
Y
E
C
Site 53
Y393
T
H
T
G
E
K
P
Y
E
C
K
Q
C
G
K
Site 54
S403
K
Q
C
G
K
A
L
S
H
R
S
S
F
R
S
Site 55
S406
G
K
A
L
S
H
R
S
S
F
R
S
H
M
I
Site 56
S407
K
A
L
S
H
R
S
S
F
R
S
H
M
I
M
Site 57
S434
G
K
A
F
V
Y
P
S
V
F
Q
R
H
E
R
Site 58
T444
Q
R
H
E
R
T
H
T
A
E
K
P
Y
K
C
Site 59
Y458
C
K
Q
C
G
K
A
Y
R
I
S
S
S
L
R
Site 60
S461
C
G
K
A
Y
R
I
S
S
S
L
R
R
H
E
Site 61
S462
G
K
A
Y
R
I
S
S
S
L
R
R
H
E
T
Site 62
S463
K
A
Y
R
I
S
S
S
L
R
R
H
E
T
T
Site 63
T469
S
S
L
R
R
H
E
T
T
H
T
G
E
K
P
Site 64
T470
S
L
R
R
H
E
T
T
H
T
G
E
K
P
Y
Site 65
T472
R
R
H
E
T
T
H
T
G
E
K
P
Y
K
C
Site 66
Y504
T
H
T
G
E
K
P
Y
E
C
K
E
C
G
K
Site 67
S514
K
E
C
G
K
A
F
S
R
F
R
Y
L
S
R
Site 68
Y518
K
A
F
S
R
F
R
Y
L
S
R
H
K
R
T
Site 69
S520
F
S
R
F
R
Y
L
S
R
H
K
R
T
H
T
Site 70
T525
Y
L
S
R
H
K
R
T
H
T
G
E
K
P
Y
Site 71
T527
S
R
H
K
R
T
H
T
G
E
K
P
Y
E
C
Site 72
Y532
T
H
T
G
E
K
P
Y
E
C
K
T
C
R
K
Site 73
S555
K
V
H
E
R
I
H
S
G
E
K
P
Y
E
C
Site 74
Y560
I
H
S
G
E
K
P
Y
E
C
K
E
C
G
K
Site 75
Y588
I
H
M
R
E
K
S
Y
E
C
P
Q
C
G
K
Site 76
T598
P
Q
C
G
K
A
F
T
H
S
R
F
L
Q
G
Site 77
T611
Q
G
H
E
K
T
H
T
G
E
N
P
Y
E
C
Site 78
Y616
T
H
T
G
E
N
P
Y
E
C
K
E
C
G
K
Site 79
S627
E
C
G
K
A
F
A
S
L
S
S
L
H
R
H
Site 80
S629
G
K
A
F
A
S
L
S
S
L
H
R
H
K
K
Site 81
S630
K
A
F
A
S
L
S
S
L
H
R
H
K
K
T
Site 82
T642
K
K
T
H
W
K
K
T
H
T
G
E
N
P
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation