KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
SEC15L2
Full Name:
Exocyst complex component 6B
Alias:
EXC6B; EXOC6B; Exocyst complex component Sec15B; KIAA0919; SEC15B; SEC15-like protein 2
Type:
Unknown function
Mass (Da):
78216
Number AA:
672
UniProt ID:
Q9Y2D4
International Prot ID:
IPI00294133
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000145
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0015031
GO:0006904
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
G
K
M
A
E
A
E
S
L
E
T
A
A
E
H
Site 2
S27
R
I
L
R
E
I
E
S
T
D
T
A
C
I
G
Site 3
T30
R
E
I
E
S
T
D
T
A
C
I
G
P
T
L
Site 4
S39
C
I
G
P
T
L
R
S
V
Y
D
G
E
E
H
Site 5
Y41
G
P
T
L
R
S
V
Y
D
G
E
E
H
G
R
Site 6
T55
R
F
M
E
K
L
E
T
R
I
R
N
H
D
R
Site 7
Y72
E
K
M
C
N
F
H
Y
Q
G
F
V
D
S
I
Site 8
T99
L
K
N
Q
V
T
D
T
N
R
K
L
Q
H
E
Site 9
S128
R
L
Q
Q
R
N
I
S
A
T
V
D
K
L
M
Site 10
T130
Q
Q
R
N
I
S
A
T
V
D
K
L
M
L
C
Site 11
T153
K
L
R
D
Q
M
K
T
K
R
H
Y
P
A
L
Site 12
Y157
Q
M
K
T
K
R
H
Y
P
A
L
K
T
L
E
Site 13
T162
R
H
Y
P
A
L
K
T
L
E
H
L
E
H
T
Site 14
Y170
L
E
H
L
E
H
T
Y
L
P
Q
V
S
H
Y
Site 15
S198
R
E
E
I
K
D
V
S
M
S
D
L
K
D
F
Site 16
S200
E
I
K
D
V
S
M
S
D
L
K
D
F
L
E
Site 17
S208
D
L
K
D
F
L
E
S
I
R
K
H
S
D
K
Site 18
S213
L
E
S
I
R
K
H
S
D
K
I
G
E
T
A
Site 19
S242
L
Q
Q
P
R
I
G
S
K
R
K
S
K
K
D
Site 20
S246
R
I
G
S
K
R
K
S
K
K
D
A
Y
I
I
Site 21
Y251
R
K
S
K
K
D
A
Y
I
I
F
D
T
E
I
Site 22
T256
D
A
Y
I
I
F
D
T
E
I
E
S
T
S
P
Site 23
S260
I
F
D
T
E
I
E
S
T
S
P
K
S
E
Q
Site 24
T261
F
D
T
E
I
E
S
T
S
P
K
S
E
Q
D
Site 25
S262
D
T
E
I
E
S
T
S
P
K
S
E
Q
D
S
Site 26
S265
I
E
S
T
S
P
K
S
E
Q
D
S
G
I
L
Site 27
S269
S
P
K
S
E
Q
D
S
G
I
L
D
V
E
D
Site 28
S293
A
Q
D
L
V
D
F
S
P
V
Y
R
C
L
H
Site 29
T310
S
V
L
G
A
R
E
T
F
E
N
Y
Y
R
K
Site 30
Y314
A
R
E
T
F
E
N
Y
Y
R
K
Q
R
R
K
Site 31
S331
R
L
V
L
Q
P
P
S
N
M
H
E
T
L
D
Site 32
T336
P
P
S
N
M
H
E
T
L
D
G
Y
R
K
Y
Site 33
Y340
M
H
E
T
L
D
G
Y
R
K
Y
F
N
Q
I
Site 34
Y343
T
L
D
G
Y
R
K
Y
F
N
Q
I
V
G
F
Site 35
Y369
Q
G
L
V
N
R
A
Y
I
D
E
L
W
E
M
Site 36
T387
K
T
I
A
A
L
R
T
H
S
S
Y
C
S
D
Site 37
S389
I
A
A
L
R
T
H
S
S
Y
C
S
D
P
N
Site 38
S390
A
A
L
R
T
H
S
S
Y
C
S
D
P
N
L
Site 39
Y391
A
L
R
T
H
S
S
Y
C
S
D
P
N
L
V
Site 40
S393
R
T
H
S
S
Y
C
S
D
P
N
L
V
L
D
Site 41
Y433
L
L
E
I
R
D
Q
Y
S
E
T
L
L
K
K
Site 42
S434
L
E
I
R
D
Q
Y
S
E
T
L
L
K
K
W
Site 43
S451
I
F
R
N
I
L
D
S
D
N
Y
S
P
I
P
Site 44
Y454
N
I
L
D
S
D
N
Y
S
P
I
P
V
T
S
Site 45
S455
I
L
D
S
D
N
Y
S
P
I
P
V
T
S
E
Site 46
Y465
P
V
T
S
E
E
M
Y
K
K
V
V
G
Q
F
Site 47
S491
F
P
K
K
F
P
F
S
E
F
V
P
K
V
Y
Site 48
Y498
S
E
F
V
P
K
V
Y
N
Q
I
K
E
F
I
Site 49
Y506
N
Q
I
K
E
F
I
Y
A
C
L
K
F
S
E
Site 50
T520
E
D
L
H
L
S
S
T
E
V
D
D
M
I
R
Site 51
S529
V
D
D
M
I
R
K
S
T
N
L
L
L
T
R
Site 52
T530
D
D
M
I
R
K
S
T
N
L
L
L
T
R
T
Site 53
T535
K
S
T
N
L
L
L
T
R
T
L
S
N
S
L
Site 54
T537
T
N
L
L
L
T
R
T
L
S
N
S
L
Q
N
Site 55
S541
L
T
R
T
L
S
N
S
L
Q
N
V
I
K
R
Site 56
Y572
H
L
E
K
S
C
K
Y
L
E
E
F
I
T
N
Site 57
T590
V
L
P
E
T
V
H
T
T
K
L
Y
G
T
T
Site 58
T598
T
K
L
Y
G
T
T
T
F
K
D
A
R
H
A
Site 59
Y611
H
A
A
E
E
E
I
Y
T
N
L
N
Q
K
I
Site 60
T612
A
A
E
E
E
I
Y
T
N
L
N
Q
K
I
D
Site 61
Y627
Q
F
L
Q
L
A
D
Y
D
W
M
T
G
D
L
Site 62
T631
L
A
D
Y
D
W
M
T
G
D
L
G
N
K
A
Site 63
S639
G
D
L
G
N
K
A
S
D
Y
L
V
D
L
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation