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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SSX2IP
Full Name:
Afadin- and alpha-actinin-binding protein
Alias:
ADIP; Afadin DIL domain-interacting protein; SSX2-interacting protein; Synovial sarcoma, X breakpoint 2 interacting protein
Type:
Adhesion protein
Mass (Da):
71236
Number AA:
614
UniProt ID:
Q9Y2D8
International Prot ID:
IPI00470669
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0030054
GO:0032991
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
GO:0009987
GO:0022610
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
G
D
W
M
T
V
T
D
P
G
L
S
S
E
Site 2
S13
T
V
T
D
P
G
L
S
S
E
S
K
T
I
S
Site 3
S14
V
T
D
P
G
L
S
S
E
S
K
T
I
S
Q
Site 4
S16
D
P
G
L
S
S
E
S
K
T
I
S
Q
Y
T
Site 5
T18
G
L
S
S
E
S
K
T
I
S
Q
Y
T
S
E
Site 6
S20
S
S
E
S
K
T
I
S
Q
Y
T
S
E
T
K
Site 7
S24
K
T
I
S
Q
Y
T
S
E
T
K
M
S
P
S
Site 8
S29
Y
T
S
E
T
K
M
S
P
S
S
L
Y
S
Q
Site 9
S31
S
E
T
K
M
S
P
S
S
L
Y
S
Q
Q
V
Site 10
S32
E
T
K
M
S
P
S
S
L
Y
S
Q
Q
V
L
Site 11
S35
M
S
P
S
S
L
Y
S
Q
Q
V
L
C
S
S
Site 12
S41
Y
S
Q
Q
V
L
C
S
S
I
P
L
S
K
N
Site 13
T58
S
F
F
S
A
F
C
T
E
D
N
I
E
Q
S
Site 14
T74
S
Y
L
D
Q
E
L
T
T
F
G
F
P
S
L
Site 15
T75
Y
L
D
Q
E
L
T
T
F
G
F
P
S
L
Y
Site 16
S80
L
T
T
F
G
F
P
S
L
Y
E
E
S
K
G
Site 17
Y82
T
F
G
F
P
S
L
Y
E
E
S
K
G
K
E
Site 18
T122
L
A
Q
E
N
V
E
T
Q
N
L
K
L
G
S
Site 19
S129
T
Q
N
L
K
L
G
S
D
M
D
H
L
Q
S
Site 20
S136
S
D
M
D
H
L
Q
S
C
Y
S
K
L
K
E
Site 21
S139
D
H
L
Q
S
C
Y
S
K
L
K
E
Q
L
E
Site 22
T147
K
L
K
E
Q
L
E
T
S
R
R
E
M
I
G
Site 23
S148
L
K
E
Q
L
E
T
S
R
R
E
M
I
G
L
Site 24
Y205
M
K
R
K
E
R
E
Y
N
K
L
K
E
R
L
Site 25
Y231
I
A
M
D
I
L
N
Y
V
G
R
A
D
G
K
Site 26
S241
R
A
D
G
K
R
G
S
W
R
T
G
K
T
E
Site 27
T244
G
K
R
G
S
W
R
T
G
K
T
E
A
R
N
Site 28
Y256
A
R
N
E
D
E
M
Y
K
I
L
L
N
D
Y
Site 29
Y263
Y
K
I
L
L
N
D
Y
E
Y
R
Q
K
Q
I
Site 30
Y265
I
L
L
N
D
Y
E
Y
R
Q
K
Q
I
L
M
Site 31
S290
Q
M
K
K
E
M
I
S
L
L
S
P
Q
K
K
Site 32
S293
K
E
M
I
S
L
L
S
P
Q
K
K
K
P
R
Site 33
S306
P
R
E
R
V
D
D
S
T
G
T
V
I
S
D
Site 34
T307
R
E
R
V
D
D
S
T
G
T
V
I
S
D
V
Site 35
S312
D
S
T
G
T
V
I
S
D
V
E
E
D
A
G
Site 36
S322
E
E
D
A
G
E
L
S
R
E
S
M
W
D
L
Site 37
S325
A
G
E
L
S
R
E
S
M
W
D
L
S
C
E
Site 38
S330
R
E
S
M
W
D
L
S
C
E
T
V
R
E
Q
Site 39
S341
V
R
E
Q
L
T
N
S
I
R
K
Q
W
R
I
Site 40
S351
K
Q
W
R
I
L
K
S
H
V
E
K
L
D
N
Site 41
S361
E
K
L
D
N
Q
V
S
K
V
H
L
E
G
F
Site 42
S375
F
N
D
E
D
V
I
S
R
Q
D
H
E
Q
E
Site 43
T399
Q
C
K
E
M
I
K
T
Q
Q
Q
L
L
Q
Q
Site 44
T416
A
T
A
Y
D
D
D
T
T
S
L
L
R
D
C
Site 45
T417
T
A
Y
D
D
D
T
T
S
L
L
R
D
C
Y
Site 46
S418
A
Y
D
D
D
T
T
S
L
L
R
D
C
Y
L
Site 47
Y424
T
S
L
L
R
D
C
Y
L
L
E
E
K
E
R
Site 48
S437
E
R
L
K
E
E
W
S
L
F
K
E
Q
K
K
Site 49
S452
N
F
E
R
E
R
R
S
F
T
E
A
A
I
R
Site 50
T454
E
R
E
R
R
S
F
T
E
A
A
I
R
L
G
Site 51
S473
A
F
E
E
E
R
A
S
W
L
K
Q
Q
F
L
Site 52
S497
S
E
N
V
K
L
F
S
A
F
S
G
S
S
D
Site 53
S500
V
K
L
F
S
A
F
S
G
S
S
D
W
D
N
Site 54
S521
Q
P
Q
K
K
P
H
S
V
S
N
G
S
P
V
Site 55
S523
Q
K
K
P
H
S
V
S
N
G
S
P
V
C
M
Site 56
S526
P
H
S
V
S
N
G
S
P
V
C
M
S
K
L
Site 57
S531
N
G
S
P
V
C
M
S
K
L
T
K
S
L
P
Site 58
S536
C
M
S
K
L
T
K
S
L
P
A
S
P
S
T
Site 59
S540
L
T
K
S
L
P
A
S
P
S
T
S
D
F
C
Site 60
S542
K
S
L
P
A
S
P
S
T
S
D
F
C
Q
T
Site 61
S544
L
P
A
S
P
S
T
S
D
F
C
Q
T
R
S
Site 62
S551
S
D
F
C
Q
T
R
S
C
I
S
E
H
S
S
Site 63
S554
C
Q
T
R
S
C
I
S
E
H
S
S
I
N
V
Site 64
S557
R
S
C
I
S
E
H
S
S
I
N
V
L
N
I
Site 65
S584
E
C
T
N
Q
K
W
S
V
A
S
R
P
G
S
Site 66
S587
N
Q
K
W
S
V
A
S
R
P
G
S
Q
E
G
Site 67
S591
S
V
A
S
R
P
G
S
Q
E
G
C
Y
S
G
Site 68
Y596
P
G
S
Q
E
G
C
Y
S
G
C
S
L
S
Y
Site 69
S597
G
S
Q
E
G
C
Y
S
G
C
S
L
S
Y
T
Site 70
S600
E
G
C
Y
S
G
C
S
L
S
Y
T
N
S
H
Site 71
S602
C
Y
S
G
C
S
L
S
Y
T
N
S
H
V
E
Site 72
T604
S
G
C
S
L
S
Y
T
N
S
H
V
E
K
D
Site 73
S606
C
S
L
S
Y
T
N
S
H
V
E
K
D
D
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation