PhosphoNET

           
Protein Info 
   
Short Name:  SLC9A8
Full Name:  Solute carrier family 9 (sodium,hydrogen exchanger), member 8
Alias:  DKFZp686C03237; FLJ42500; KIAA0939; MGC138418; NHE8; SL9A8; Solute carrier family 9 (sodium/hydrogen exchanger) member 8; Solute carrier family 9 (sodium/hydrogen exchanger), member 8
Type:  Ion channel, sodium/hydrogen exchanger
Mass (Da):  65422
Number AA:  581
UniProt ID:  Q9Y2E8
International Prot ID:  IPI00183933
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005794  GO:0016021   Uniprot OncoNet
Molecular Function:  GO:0031402  GO:0015385   PhosphoSite+ KinaseNET
Biological Process:  GO:0006885  GO:0006814  GO:0055085 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T15EERFPNTTHEGFNVT
Site 2S58AQQEEQSSGMTIFFS
Site 3S138LPPIIFESGYSLHKG
Site 4Y140PIIFESGYSLHKGNF
Site 5S183LGQADVISKLNMTDS
Site 6T256SDVSGWQTFLQALDY
Site 7T294KHIDLRKTPSLEFGM
Site 8Y334SGIVMSHYTHHNLSP
Site 9S492NKKDVNLSKTEKMGN
Site 10T494KDVNLSKTEKMGNTV
Site 11T500KTEKMGNTVESEHLS
Site 12S507TVESEHLSELTEEEY
Site 13Y514SELTEEEYEAHYIRR
Site 14Y518EEEYEAHYIRRQDLK
Site 15T540PFFTRRLTQEDLHHG
Site 16T544PFFTRRLTQEDLHHG
Site 17Y563KTLTNKWYEEVRQGP
Site 18S571EEVRQGPSGSEDDEQ
Site 19S573VRQGPSGSEDDEQEL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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