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Updated November 2019
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Protein Info
Short Name:
KIAA0947
Full Name:
Uncharacterized protein KIAA0947
Alias:
K0947; LOC23379
Type:
Unknown function
Mass (Da):
247889
Number AA:
2266
UniProt ID:
Q9Y2F5
International Prot ID:
IPI00738216
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
M
P
G
E
T
H
S
A
A
P
G
T
A
A
Site 2
T13
T
H
S
A
A
P
G
T
A
A
D
L
S
R
C
Site 3
S18
P
G
T
A
A
D
L
S
R
C
Q
G
C
A
S
Site 4
S25
S
R
C
Q
G
C
A
S
L
Q
Q
N
L
N
E
Site 5
S69
Q
F
A
R
R
E
N
S
N
L
H
H
Q
V
E
Site 6
S83
E
E
M
L
Q
K
I
S
P
L
Q
K
C
Q
E
Site 7
S94
K
C
Q
E
E
L
G
S
L
K
A
E
L
E
E
Site 8
S104
A
E
L
E
E
K
K
S
S
L
K
L
Y
Q
D
Site 9
S105
E
L
E
E
K
K
S
S
L
K
L
Y
Q
D
T
Site 10
Y109
K
K
S
S
L
K
L
Y
Q
D
T
H
Q
E
Y
Site 11
Y116
Y
Q
D
T
H
Q
E
Y
A
R
V
K
E
E
C
Site 12
S126
V
K
E
E
C
L
K
S
D
A
Q
K
K
K
L
Site 13
T168
L
E
K
E
F
K
K
T
Q
E
R
L
D
E
F
Site 14
S176
Q
E
R
L
D
E
F
S
K
Q
K
N
E
K
E
Site 15
T189
K
E
L
R
H
I
G
T
Q
I
S
S
D
S
Y
Site 16
S192
R
H
I
G
T
Q
I
S
S
D
S
Y
G
S
I
Site 17
S193
H
I
G
T
Q
I
S
S
D
S
Y
G
S
I
D
Site 18
S195
G
T
Q
I
S
S
D
S
Y
G
S
I
D
K
R
Site 19
Y196
T
Q
I
S
S
D
S
Y
G
S
I
D
K
R
K
Site 20
T218
L
W
L
C
V
N
T
T
H
R
L
P
G
E
G
Site 21
T238
E
K
P
A
K
A
I
T
S
S
R
V
P
G
E
Site 22
S239
K
P
A
K
A
I
T
S
S
R
V
P
G
E
D
Site 23
S240
P
A
K
A
I
T
S
S
R
V
P
G
E
D
G
Site 24
T248
R
V
P
G
E
D
G
T
L
P
P
T
Q
G
S
Site 25
T252
E
D
G
T
L
P
P
T
Q
G
S
P
L
R
T
Site 26
S255
T
L
P
P
T
Q
G
S
P
L
R
T
S
N
V
Site 27
T259
T
Q
G
S
P
L
R
T
S
N
V
Q
T
C
L
Site 28
S260
Q
G
S
P
L
R
T
S
N
V
Q
T
C
L
T
Site 29
T264
L
R
T
S
N
V
Q
T
C
L
T
K
L
S
M
Site 30
S288
N
V
E
K
Q
S
S
S
G
T
N
C
S
S
D
Site 31
T290
E
K
Q
S
S
S
G
T
N
C
S
S
D
H
V
Site 32
S293
S
S
S
G
T
N
C
S
S
D
H
V
F
N
E
Site 33
S294
S
S
G
T
N
C
S
S
D
H
V
F
N
E
N
Site 34
S310
N
L
E
V
L
V
Q
S
H
R
D
G
G
S
T
Site 35
S316
Q
S
H
R
D
G
G
S
T
E
F
V
D
H
D
Site 36
T317
S
H
R
D
G
G
S
T
E
F
V
D
H
D
H
Site 37
S345
K
L
P
P
P
L
L
S
P
V
P
S
P
P
P
Site 38
S349
P
L
L
S
P
V
P
S
P
P
P
M
S
S
P
Site 39
S354
V
P
S
P
P
P
M
S
S
P
H
P
G
S
L
Site 40
S355
P
S
P
P
P
M
S
S
P
H
P
G
S
L
P
Site 41
S360
M
S
S
P
H
P
G
S
L
P
S
S
F
A
P
Site 42
S364
H
P
G
S
L
P
S
S
F
A
P
E
T
Y
F
Site 43
T369
P
S
S
F
A
P
E
T
Y
F
G
E
Y
T
D
Site 44
Y374
P
E
T
Y
F
G
E
Y
T
D
S
S
D
N
D
Site 45
S377
Y
F
G
E
Y
T
D
S
S
D
N
D
S
V
Q
Site 46
S378
F
G
E
Y
T
D
S
S
D
N
D
S
V
Q
L
Site 47
S382
T
D
S
S
D
N
D
S
V
Q
L
R
N
S
A
Site 48
S388
D
S
V
Q
L
R
N
S
A
E
S
V
S
E
D
Site 49
S391
Q
L
R
N
S
A
E
S
V
S
E
D
D
T
T
Site 50
S393
R
N
S
A
E
S
V
S
E
D
D
T
T
E
S
Site 51
T397
E
S
V
S
E
D
D
T
T
E
S
Q
N
Y
F
Site 52
T398
S
V
S
E
D
D
T
T
E
S
Q
N
Y
F
G
Site 53
S400
S
E
D
D
T
T
E
S
Q
N
Y
F
G
S
L
Site 54
Y403
D
T
T
E
S
Q
N
Y
F
G
S
L
R
K
N
Site 55
S406
E
S
Q
N
Y
F
G
S
L
R
K
N
K
G
S
Site 56
S413
S
L
R
K
N
K
G
S
G
T
W
E
E
K
P
Site 57
T415
R
K
N
K
G
S
G
T
W
E
E
K
P
K
S
Site 58
S422
T
W
E
E
K
P
K
S
H
E
A
I
Q
A
L
Site 59
T444
V
T
T
S
G
L
E
T
F
T
A
T
L
R
E
Site 60
T446
T
S
G
L
E
T
F
T
A
T
L
R
E
S
S
Site 61
T448
G
L
E
T
F
T
A
T
L
R
E
S
S
A
T
Site 62
S452
F
T
A
T
L
R
E
S
S
A
T
H
S
L
V
Site 63
S453
T
A
T
L
R
E
S
S
A
T
H
S
L
V
G
Site 64
T455
T
L
R
E
S
S
A
T
H
S
L
V
G
E
K
Site 65
S457
R
E
S
S
A
T
H
S
L
V
G
E
K
H
W
Site 66
T465
L
V
G
E
K
H
W
T
T
A
S
R
S
M
S
Site 67
T466
V
G
E
K
H
W
T
T
A
S
R
S
M
S
D
Site 68
S468
E
K
H
W
T
T
A
S
R
S
M
S
D
R
K
Site 69
S470
H
W
T
T
A
S
R
S
M
S
D
R
K
R
D
Site 70
S472
T
T
A
S
R
S
M
S
D
R
K
R
D
I
L
Site 71
T484
D
I
L
H
E
T
K
T
Q
M
E
V
R
E
M
Site 72
S494
E
V
R
E
M
D
K
S
V
Q
T
E
K
T
I
Site 73
T500
K
S
V
Q
T
E
K
T
I
H
K
L
T
R
G
Site 74
S514
G
L
C
I
E
R
L
S
A
S
P
A
Q
E
K
Site 75
S516
C
I
E
R
L
S
A
S
P
A
Q
E
K
E
A
Site 76
S528
K
E
A
A
P
G
K
S
E
L
C
S
S
P
L
Site 77
S532
P
G
K
S
E
L
C
S
S
P
L
G
K
R
P
Site 78
S533
G
K
S
E
L
C
S
S
P
L
G
K
R
P
L
Site 79
S546
P
L
N
E
L
M
E
S
E
G
K
T
V
L
S
Site 80
T550
L
M
E
S
E
G
K
T
V
L
S
K
M
M
G
Site 81
S553
S
E
G
K
T
V
L
S
K
M
M
G
S
P
K
Site 82
S558
V
L
S
K
M
M
G
S
P
K
S
E
F
T
K
Site 83
S561
K
M
M
G
S
P
K
S
E
F
T
K
W
T
R
Site 84
T573
W
T
R
I
N
E
I
T
S
E
P
D
R
I
T
Site 85
T580
T
S
E
P
D
R
I
T
V
S
G
H
F
H
R
Site 86
S582
E
P
D
R
I
T
V
S
G
H
F
H
R
L
S
Site 87
S589
S
G
H
F
H
R
L
S
R
E
L
E
K
E
K
Site 88
T599
L
E
K
E
K
E
D
T
Q
G
F
T
L
G
E
Site 89
T603
K
E
D
T
Q
G
F
T
L
G
E
S
P
E
S
Site 90
S607
Q
G
F
T
L
G
E
S
P
E
S
E
D
D
D
Site 91
S610
T
L
G
E
S
P
E
S
E
D
D
D
S
G
D
Site 92
S615
P
E
S
E
D
D
D
S
G
D
G
M
D
V
A
Site 93
T628
V
A
G
L
D
I
E
T
S
F
S
S
S
S
T
Site 94
S629
A
G
L
D
I
E
T
S
F
S
S
S
S
T
L
Site 95
S640
S
S
T
L
V
A
L
S
V
G
S
N
P
Q
S
Site 96
S643
L
V
A
L
S
V
G
S
N
P
Q
S
S
S
G
Site 97
S647
S
V
G
S
N
P
Q
S
S
S
G
L
D
C
G
Site 98
S648
V
G
S
N
P
Q
S
S
S
G
L
D
C
G
N
Site 99
S649
G
S
N
P
Q
S
S
S
G
L
D
C
G
N
D
Site 100
T657
G
L
D
C
G
N
D
T
D
I
T
T
K
V
F
Site 101
T660
C
G
N
D
T
D
I
T
T
K
V
F
S
T
E
Site 102
T661
G
N
D
T
D
I
T
T
K
V
F
S
T
E
P
Site 103
S671
F
S
T
E
P
H
H
S
E
H
K
L
Q
T
K
Site 104
T679
E
H
K
L
Q
T
K
T
L
N
T
L
H
L
Q
Site 105
S687
L
N
T
L
H
L
Q
S
E
P
P
E
C
S
I
Site 106
S702
G
G
N
N
L
E
N
S
L
C
A
L
S
P
E
Site 107
S707
E
N
S
L
C
A
L
S
P
E
L
G
A
S
N
Site 108
S713
L
S
P
E
L
G
A
S
N
F
N
D
Q
K
S
Site 109
S720
S
N
F
N
D
Q
K
S
S
G
I
E
Y
T
K
Site 110
Y725
Q
K
S
S
G
I
E
Y
T
K
V
V
K
G
L
Site 111
T733
T
K
V
V
K
G
L
T
K
I
H
S
L
P
R
Site 112
S737
K
G
L
T
K
I
H
S
L
P
R
S
V
F
M
Site 113
S741
K
I
H
S
L
P
R
S
V
F
M
K
A
T
K
Site 114
S754
T
K
D
G
Q
C
E
S
Q
D
P
R
I
E
L
Site 115
T762
Q
D
P
R
I
E
L
T
L
N
K
P
D
F
T
Site 116
T769
T
L
N
K
P
D
F
T
S
L
I
G
S
Q
A
Site 117
S770
L
N
K
P
D
F
T
S
L
I
G
S
Q
A
A
Site 118
S788
S
G
L
G
F
V
K
S
T
S
W
H
H
S
D
Site 119
S790
L
G
F
V
K
S
T
S
W
H
H
S
D
L
L
Site 120
S794
K
S
T
S
W
H
H
S
D
L
L
R
K
G
G
Site 121
S804
L
R
K
G
G
E
E
S
L
R
A
K
S
E
H
Site 122
S809
E
E
S
L
R
A
K
S
E
H
E
Q
K
T
S
Site 123
S816
S
E
H
E
Q
K
T
S
H
Q
L
Q
K
A
M
Site 124
T832
F
L
Q
N
R
G
P
T
P
K
P
D
L
L
R
Site 125
T849
N
N
P
V
E
F
K
T
T
A
S
V
L
P
N
Site 126
T850
N
P
V
E
F
K
T
T
A
S
V
L
P
N
Q
Site 127
S859
S
V
L
P
N
Q
V
S
V
I
T
K
Q
T
R
Site 128
S872
T
R
P
E
K
V
Q
S
A
K
L
E
H
L
R
Site 129
T886
R
P
H
R
V
E
P
T
L
V
T
E
N
S
G
Site 130
S892
P
T
L
V
T
E
N
S
G
N
K
T
G
M
S
Site 131
T896
T
E
N
S
G
N
K
T
G
M
S
T
I
A
K
Site 132
S899
S
G
N
K
T
G
M
S
T
I
A
K
C
D
G
Site 133
T911
C
D
G
E
R
D
D
T
T
Q
N
I
T
E
V
Site 134
T912
D
G
E
R
D
D
T
T
Q
N
I
T
E
V
A
Site 135
S925
V
A
A
V
K
S
I
S
P
E
V
S
A
S
R
Site 136
S929
K
S
I
S
P
E
V
S
A
S
R
R
K
L
D
Site 137
S931
I
S
P
E
V
S
A
S
R
R
K
L
D
F
N
Site 138
S939
R
R
K
L
D
F
N
S
P
G
G
S
S
P
V
Site 139
S943
D
F
N
S
P
G
G
S
S
P
V
E
N
S
D
Site 140
S944
F
N
S
P
G
G
S
S
P
V
E
N
S
D
C
Site 141
S949
G
S
S
P
V
E
N
S
D
C
S
T
N
S
R
Site 142
S952
P
V
E
N
S
D
C
S
T
N
S
R
L
S
F
Site 143
T953
V
E
N
S
D
C
S
T
N
S
R
L
S
F
S
Site 144
S955
N
S
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S
A
V
Site 296
S1891
N
E
E
R
S
C
S
S
P
A
V
S
A
V
S
Site 297
S1903
A
V
S
Q
L
P
L
S
P
K
E
T
V
E
S
Site 298
T1907
L
P
L
S
P
K
E
T
V
E
S
H
D
K
A
Site 299
S1910
S
P
K
E
T
V
E
S
H
D
K
A
I
A
N
Site 300
S1926
L
K
K
I
A
E
F
S
F
D
L
L
P
V
I
Site 301
Y1938
P
V
I
R
S
H
V
Y
V
G
N
I
S
K
K
Site 302
Y1957
D
Q
E
K
E
V
V
Y
E
F
S
T
T
K
K
Site 303
Y1989
K
I
S
M
D
H
N
Y
I
H
A
L
C
R
V
Site 304
S2016
R
A
R
L
F
C
Y
S
L
L
K
E
D
F
P
Site 305
S2025
L
K
E
D
F
P
E
S
E
K
L
T
L
F
I
Site 306
T2097
T
I
Q
L
C
P
K
T
E
F
Q
P
S
E
K
Site 307
S2102
P
K
T
E
F
Q
P
S
E
K
F
G
E
D
L
Site 308
S2110
E
K
F
G
E
D
L
S
D
N
T
W
E
Y
I
Site 309
T2113
G
E
D
L
S
D
N
T
W
E
Y
I
F
A
I
Site 310
S2187
G
L
K
E
G
F
P
S
A
V
K
N
I
S
S
Site 311
S2226
A
L
C
D
L
S
P
S
N
P
A
E
I
S
K
Site 312
S2243
E
A
W
R
R
E
A
S
K
S
V
P
S
A
I
Site 313
S2245
W
R
R
E
A
S
K
S
V
P
S
A
I
V
S
Site 314
S2261
L
E
E
V
S
A
L
S
T
E
E
L
G
_
_
Site 315
T2262
E
E
V
S
A
L
S
T
E
E
L
G
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation