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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Nlp
Full Name:
Ninein-like protein
Alias:
KIAA0980; NINLP
Type:
Centrosomal protein, microtubule organizing protein
Mass (Da):
156344
Number AA:
1382
UniProt ID:
Q9Y2I6
International Prot ID:
IPI00294173
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005813
GO:0005829
GO:0005874
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
D
E
E
E
N
H
Y
V
S
Q
L
R
E
V
Site 2
S10
E
E
E
N
H
Y
V
S
Q
L
R
E
V
Y
S
Site 3
Y16
V
S
Q
L
R
E
V
Y
S
S
C
D
T
T
G
Site 4
S17
S
Q
L
R
E
V
Y
S
S
C
D
T
T
G
T
Site 5
S18
Q
L
R
E
V
Y
S
S
C
D
T
T
G
T
G
Site 6
T21
E
V
Y
S
S
C
D
T
T
G
T
G
F
L
D
Site 7
T22
V
Y
S
S
C
D
T
T
G
T
G
F
L
D
R
Site 8
S83
S
N
A
G
V
R
P
S
D
E
D
S
S
S
L
Site 9
S87
V
R
P
S
D
E
D
S
S
S
L
E
S
A
A
Site 10
S88
R
P
S
D
E
D
S
S
S
L
E
S
A
A
S
Site 11
S89
P
S
D
E
D
S
S
S
L
E
S
A
A
S
S
Site 12
S92
E
D
S
S
S
L
E
S
A
A
S
S
A
I
P
Site 13
S95
S
S
L
E
S
A
A
S
S
A
I
P
P
K
Y
Site 14
S96
S
L
E
S
A
A
S
S
A
I
P
P
K
Y
V
Site 15
Y102
S
S
A
I
P
P
K
Y
V
N
G
S
K
W
Y
Site 16
Y109
Y
V
N
G
S
K
W
Y
G
R
R
S
R
P
E
Site 17
S113
S
K
W
Y
G
R
R
S
R
P
E
L
C
D
A
Site 18
T122
P
E
L
C
D
A
A
T
E
A
R
R
V
P
E
Site 19
S135
P
E
Q
Q
T
Q
A
S
L
K
S
H
L
W
R
Site 20
S138
Q
T
Q
A
S
L
K
S
H
L
W
R
S
A
S
Site 21
S143
L
K
S
H
L
W
R
S
A
S
L
E
S
V
E
Site 22
S145
S
H
L
W
R
S
A
S
L
E
S
V
E
S
P
Site 23
S148
W
R
S
A
S
L
E
S
V
E
S
P
K
S
D
Site 24
S151
A
S
L
E
S
V
E
S
P
K
S
D
E
E
A
Site 25
S154
E
S
V
E
S
P
K
S
D
E
E
A
E
S
T
Site 26
S160
K
S
D
E
E
A
E
S
T
K
E
A
Q
N
E
Site 27
T161
S
D
E
E
A
E
S
T
K
E
A
Q
N
E
L
Site 28
S180
G
Q
L
Q
T
W
D
S
E
D
F
G
S
P
Q
Site 29
S185
W
D
S
E
D
F
G
S
P
Q
K
S
C
S
P
Site 30
S189
D
F
G
S
P
Q
K
S
C
S
P
S
F
D
T
Site 31
S191
G
S
P
Q
K
S
C
S
P
S
F
D
T
P
E
Site 32
S193
P
Q
K
S
C
S
P
S
F
D
T
P
E
S
Q
Site 33
T196
S
C
S
P
S
F
D
T
P
E
S
Q
I
R
G
Site 34
S199
P
S
F
D
T
P
E
S
Q
I
R
G
V
W
E
Site 35
S213
E
E
L
G
V
G
S
S
G
H
L
S
E
Q
E
Site 36
S254
Q
D
G
D
G
K
V
S
L
E
E
F
Q
L
G
Site 37
S274
P
A
L
L
L
E
S
S
T
R
V
K
P
S
K
Site 38
S280
S
S
T
R
V
K
P
S
K
A
W
S
H
Y
Q
Site 39
S284
V
K
P
S
K
A
W
S
H
Y
Q
V
P
E
E
Site 40
Y286
P
S
K
A
W
S
H
Y
Q
V
P
E
E
S
G
Site 41
T296
P
E
E
S
G
C
H
T
T
T
T
S
S
L
V
Site 42
T297
E
E
S
G
C
H
T
T
T
T
S
S
L
V
S
Site 43
T298
E
S
G
C
H
T
T
T
T
S
S
L
V
S
L
Site 44
S313
C
S
S
L
R
L
F
S
S
I
D
D
G
S
G
Site 45
S314
S
S
L
R
L
F
S
S
I
D
D
G
S
G
F
Site 46
S319
F
S
S
I
D
D
G
S
G
F
A
F
P
D
Q
Site 47
S345
N
G
R
E
I
L
Q
S
L
D
F
S
V
D
E
Site 48
T369
A
L
D
N
E
L
M
T
V
D
S
A
V
Q
Q
Site 49
S426
K
E
M
D
D
C
H
S
T
L
E
Q
L
T
E
Site 50
T427
E
M
D
D
C
H
S
T
L
E
Q
L
T
E
K
Site 51
S448
Q
G
Y
R
E
R
L
S
L
L
R
S
E
V
E
Site 52
S452
E
R
L
S
L
L
R
S
E
V
E
A
E
R
E
Site 53
T491
A
G
L
R
E
K
L
T
L
A
L
K
E
N
S
Site 54
S512
V
E
V
V
E
K
L
S
D
S
E
R
L
A
L
Site 55
S514
V
V
E
K
L
S
D
S
E
R
L
A
L
K
L
Site 56
S585
R
L
P
K
N
R
H
S
P
S
W
S
P
D
G
Site 57
S587
P
K
N
R
H
S
P
S
W
S
P
D
G
R
R
Site 58
S589
N
R
H
S
P
S
W
S
P
D
G
R
R
R
Q
Site 59
T638
D
L
R
T
Q
L
E
T
K
V
N
Y
Y
E
R
Site 60
Y642
Q
L
E
T
K
V
N
Y
Y
E
R
E
I
A
A
Site 61
Y643
L
E
T
K
V
N
Y
Y
E
R
E
I
A
A
L
Site 62
S670
Q
A
R
R
R
E
V
S
V
L
E
G
Q
K
A
Site 63
S686
L
E
E
L
H
E
K
S
Q
E
V
I
W
G
L
Site 64
T700
L
Q
E
Q
L
Q
D
T
A
R
G
P
E
P
E
Site 65
S728
G
L
A
L
R
H
H
S
H
L
Q
Q
I
R
R
Site 66
S742
R
E
A
E
A
E
L
S
G
E
L
S
G
L
G
Site 67
T758
L
P
A
R
R
D
L
T
L
E
L
E
E
P
P
Site 68
S773
Q
G
P
L
P
R
G
S
Q
R
S
E
Q
L
E
Site 69
S776
L
P
R
G
S
Q
R
S
E
Q
L
E
L
E
R
Site 70
S792
L
K
L
Q
P
C
A
S
E
K
R
A
Q
M
C
Site 71
S801
K
R
A
Q
M
C
V
S
L
A
L
E
E
E
E
Site 72
S821
G
K
R
V
D
G
P
S
L
E
A
E
M
Q
A
Site 73
S869
A
P
G
D
G
R
E
S
E
E
A
A
G
A
G
Site 74
T885
R
R
R
Q
A
Q
D
T
E
A
T
Q
S
P
A
Site 75
T888
Q
A
Q
D
T
E
A
T
Q
S
P
A
P
A
P
Site 76
S890
Q
D
T
E
A
T
Q
S
P
A
P
A
P
A
P
Site 77
S899
A
P
A
P
A
P
A
S
H
G
P
S
E
R
W
Site 78
S903
A
P
A
S
H
G
P
S
E
R
W
S
R
M
Q
Site 79
T946
R
E
L
P
L
L
G
T
E
R
D
A
S
Q
T
Site 80
S951
L
G
T
E
R
D
A
S
Q
T
Q
P
R
M
W
Site 81
T953
T
E
R
D
A
S
Q
T
Q
P
R
M
W
E
P
Site 82
S967
P
P
L
R
P
A
A
S
C
R
G
Q
A
E
R
Site 83
S985
I
Q
E
E
R
A
R
S
W
S
R
G
T
Q
E
Site 84
S987
E
E
R
A
R
S
W
S
R
G
T
Q
E
Q
A
Site 85
T990
A
R
S
W
S
R
G
T
Q
E
Q
A
S
E
Q
Site 86
S1013
E
P
G
C
H
K
H
S
V
E
V
A
R
R
G
Site 87
S1021
V
E
V
A
R
R
G
S
L
P
S
H
L
Q
L
Site 88
S1024
A
R
R
G
S
L
P
S
H
L
Q
L
A
D
P
Site 89
S1090
R
L
E
F
H
R
L
S
E
E
N
T
L
L
K
Site 90
T1094
H
R
L
S
E
E
N
T
L
L
K
N
D
L
G
Site 91
S1112
Q
E
L
E
A
A
E
S
T
H
D
A
Q
R
K
Site 92
S1133
K
D
K
E
K
A
C
S
E
M
E
V
L
N
R
Site 93
Y1145
L
N
R
Q
N
Q
N
Y
K
D
Q
L
S
Q
L
Site 94
S1150
Q
N
Y
K
D
Q
L
S
Q
L
N
V
R
V
L
Site 95
S1164
L
Q
L
G
Q
E
A
S
T
H
Q
A
Q
N
E
Site 96
T1176
Q
N
E
E
H
R
V
T
I
Q
M
L
T
Q
S
Site 97
S1183
T
I
Q
M
L
T
Q
S
L
E
E
V
V
R
S
Site 98
S1190
S
L
E
E
V
V
R
S
G
Q
Q
Q
S
D
Q
Site 99
S1220
Q
S
L
Q
L
P
W
S
E
L
T
Q
T
L
E
Site 100
T1225
P
W
S
E
L
T
Q
T
L
E
E
S
Q
D
Q
Site 101
S1267
A
E
L
H
R
L
L
S
L
Q
G
E
Q
A
R
Site 102
S1326
Q
F
E
K
N
T
K
S
D
L
L
L
K
E
L
Site 103
T1347
L
V
R
A
L
Q
A
T
E
E
K
Q
R
G
A
Site 104
S1373
R
A
L
N
K
L
V
S
R
I
A
P
A
A
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation