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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AMOTL2
Full Name:
Angiomotin-like protein 2
Alias:
AMOL2; Angiomotin like 2; Angiomotin-like 2; LCCP; Leman coiled-coil; Leman coiled-coil protein
Type:
Adhesion
Mass (Da):
85750
Number AA:
779
UniProt ID:
Q9Y2J4
International Prot ID:
IPI00032236
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
R
T
L
E
D
S
S
G
T
V
L
H
R
Site 2
Y22
L
I
Q
E
Q
L
R
Y
G
N
L
T
E
T
R
Site 3
T26
Q
L
R
Y
G
N
L
T
E
T
R
T
L
L
A
Site 4
T45
A
L
R
G
G
A
G
T
G
G
T
G
S
P
Q
Site 5
T48
G
G
A
G
T
G
G
T
G
S
P
Q
A
S
L
Site 6
S50
A
G
T
G
G
T
G
S
P
Q
A
S
L
E
I
Site 7
S54
G
T
G
S
P
Q
A
S
L
E
I
L
A
P
E
Site 8
S63
E
I
L
A
P
E
D
S
Q
V
L
Q
Q
A
T
Site 9
Y92
H
L
A
E
N
T
L
Y
R
L
C
P
Q
P
S
Site 10
S99
Y
R
L
C
P
Q
P
S
K
G
E
E
L
P
T
Site 11
T106
S
K
G
E
E
L
P
T
Y
E
E
A
K
A
H
Site 12
Y107
K
G
E
E
L
P
T
Y
E
E
A
K
A
H
S
Site 13
S140
P
R
G
A
P
G
G
S
R
R
Q
D
E
A
L
Site 14
S157
L
R
H
G
H
V
R
S
L
S
E
R
L
L
Q
Site 15
S159
H
G
H
V
R
S
L
S
E
R
L
L
Q
L
S
Site 16
S166
S
E
R
L
L
Q
L
S
L
E
R
N
G
A
R
Site 17
S176
R
N
G
A
R
A
P
S
H
M
S
S
S
H
S
Site 18
S179
A
R
A
P
S
H
M
S
S
S
H
S
F
P
Q
Site 19
S180
R
A
P
S
H
M
S
S
S
H
S
F
P
Q
L
Site 20
S181
A
P
S
H
M
S
S
S
H
S
F
P
Q
L
A
Site 21
S183
S
H
M
S
S
S
H
S
F
P
Q
L
A
R
N
Site 22
S206
P
P
A
E
G
P
E
S
R
G
P
P
P
Q
Y
Site 23
Y213
S
R
G
P
P
P
Q
Y
P
H
V
V
L
A
H
Site 24
Y231
T
A
V
T
D
P
R
Y
R
A
R
G
S
P
H
Site 25
S236
P
R
Y
R
A
R
G
S
P
H
F
Q
H
A
E
Site 26
Y264
Q
Q
Q
Q
Q
Y
Q
Y
L
Q
Q
S
Q
E
H
Site 27
S268
Q
Y
Q
Y
L
Q
Q
S
Q
E
H
P
P
P
P
Site 28
S287
L
G
H
G
P
L
S
S
L
S
P
P
A
V
E
Site 29
S289
H
G
P
L
S
S
L
S
P
P
A
V
E
G
P
Site 30
S298
P
A
V
E
G
P
V
S
A
Q
A
S
S
A
T
Site 31
S302
G
P
V
S
A
Q
A
S
S
A
T
S
G
S
A
Site 32
S303
P
V
S
A
Q
A
S
S
A
T
S
G
S
A
H
Site 33
S306
A
Q
A
S
S
A
T
S
G
S
A
H
L
A
Q
Site 34
S338
L
Q
R
E
L
E
S
S
A
E
K
A
G
R
I
Site 35
S350
G
R
I
E
K
L
E
S
E
I
Q
R
L
S
E
Site 36
S356
E
S
E
I
Q
R
L
S
E
A
H
E
S
L
T
Site 37
S361
R
L
S
E
A
H
E
S
L
T
R
A
S
S
K
Site 38
T363
S
E
A
H
E
S
L
T
R
A
S
S
K
R
E
Site 39
S366
H
E
S
L
T
R
A
S
S
K
R
E
A
L
E
Site 40
S367
E
S
L
T
R
A
S
S
K
R
E
A
L
E
K
Site 41
T375
K
R
E
A
L
E
K
T
M
R
N
K
M
D
S
Site 42
S382
T
M
R
N
K
M
D
S
E
M
R
R
L
Q
D
Site 43
S400
D
L
R
E
R
L
E
S
A
N
R
R
L
A
S
Site 44
S407
S
A
N
R
R
L
A
S
K
T
Q
E
A
Q
A
Site 45
T409
N
R
R
L
A
S
K
T
Q
E
A
Q
A
G
S
Site 46
Y482
E
L
R
K
K
Q
A
Y
V
E
K
V
E
R
L
Site 47
T512
Q
L
E
L
R
L
R
T
R
L
E
Q
E
L
K
Site 48
S534
Q
A
G
A
P
G
G
S
S
G
S
G
G
S
P
Site 49
S535
A
G
A
P
G
G
S
S
G
S
G
G
S
P
E
Site 50
S540
G
S
S
G
S
G
G
S
P
E
L
S
A
L
R
Site 51
S544
S
G
G
S
P
E
L
S
A
L
R
L
S
E
Q
Site 52
S549
E
L
S
A
L
R
L
S
E
Q
L
R
E
K
E
Site 53
T567
L
A
L
E
A
D
M
T
K
W
E
Q
K
Y
L
Site 54
Y573
M
T
K
W
E
Q
K
Y
L
E
E
R
A
M
R
Site 55
T596
T
A
A
A
Q
R
D
T
T
L
I
R
H
S
P
Site 56
T597
A
A
A
Q
R
D
T
T
L
I
R
H
S
P
Q
Site 57
S602
D
T
T
L
I
R
H
S
P
Q
P
S
P
S
S
Site 58
S606
I
R
H
S
P
Q
P
S
P
S
S
S
F
N
E
Site 59
S608
H
S
P
Q
P
S
P
S
S
S
F
N
E
G
L
Site 60
S609
S
P
Q
P
S
P
S
S
S
F
N
E
G
L
L
Site 61
S610
P
Q
P
S
P
S
S
S
F
N
E
G
L
L
T
Site 62
T617
S
F
N
E
G
L
L
T
G
G
H
R
H
Q
E
Site 63
S650
I
K
V
L
Q
Q
R
S
R
R
D
P
G
K
A
Site 64
S661
P
G
K
A
I
Q
G
S
L
R
P
A
K
S
V
Site 65
S667
G
S
L
R
P
A
K
S
V
P
S
V
F
A
A
Site 66
T679
F
A
A
A
A
A
G
T
Q
G
W
Q
G
L
S
Site 67
S686
T
Q
G
W
Q
G
L
S
S
S
E
R
Q
T
A
Site 68
S687
Q
G
W
Q
G
L
S
S
S
E
R
Q
T
A
D
Site 69
S688
G
W
Q
G
L
S
S
S
E
R
Q
T
A
D
A
Site 70
T692
L
S
S
S
E
R
Q
T
A
D
A
P
A
R
L
Site 71
T700
A
D
A
P
A
R
L
T
T
D
R
A
P
T
E
Site 72
T701
D
A
P
A
R
L
T
T
D
R
A
P
T
E
E
Site 73
T706
L
T
T
D
R
A
P
T
E
E
P
V
V
T
A
Site 74
T712
P
T
E
E
P
V
V
T
A
P
P
A
A
H
A
Site 75
S723
A
A
H
A
K
H
G
S
R
D
G
S
T
Q
T
Site 76
S727
K
H
G
S
R
D
G
S
T
Q
T
D
G
P
P
Site 77
T728
H
G
S
R
D
G
S
T
Q
T
D
G
P
P
D
Site 78
T730
S
R
D
G
S
T
Q
T
D
G
P
P
D
S
T
Site 79
S736
Q
T
D
G
P
P
D
S
T
S
T
C
L
P
P
Site 80
T737
T
D
G
P
P
D
S
T
S
T
C
L
P
P
E
Site 81
S738
D
G
P
P
D
S
T
S
T
C
L
P
P
E
P
Site 82
S747
C
L
P
P
E
P
D
S
L
L
G
C
S
S
S
Site 83
S753
D
S
L
L
G
C
S
S
S
Q
R
A
A
S
L
Site 84
S754
S
L
L
G
C
S
S
S
Q
R
A
A
S
L
D
Site 85
S759
S
S
S
Q
R
A
A
S
L
D
S
V
A
T
S
Site 86
S762
Q
R
A
A
S
L
D
S
V
A
T
S
R
V
Q
Site 87
S766
S
L
D
S
V
A
T
S
R
V
Q
D
L
S
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation