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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PADI2
Full Name:
Alias:
PAD-H19;Peptidylarginine deiminase II;Protein-arginine deiminase type II
Type:
Mass (Da):
75564
Number AA:
665
UniProt ID:
Q9Y2J8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
L
R
E
R
T
V
R
L
Q
Y
G
S
Site 2
Y11
E
R
T
V
R
L
Q
Y
G
S
R
V
E
A
V
Site 3
S31
Y
L
W
T
D
V
Y
S
A
A
P
A
G
A
Q
Site 4
T39
A
A
P
A
G
A
Q
T
F
S
L
K
H
S
E
Site 5
S41
P
A
G
A
Q
T
F
S
L
K
H
S
E
H
V
Site 6
T63
G
E
A
E
E
V
A
T
N
G
K
Q
R
W
L
Site 7
S72
G
K
Q
R
W
L
L
S
P
S
T
T
L
R
V
Site 8
S74
Q
R
W
L
L
S
P
S
T
T
L
R
V
T
M
Site 9
T75
R
W
L
L
S
P
S
T
T
L
R
V
T
M
S
Site 10
T76
W
L
L
S
P
S
T
T
L
R
V
T
M
S
Q
Site 11
T80
P
S
T
T
L
R
V
T
M
S
Q
A
S
T
E
Site 12
S82
T
T
L
R
V
T
M
S
Q
A
S
T
E
A
S
Site 13
S85
R
V
T
M
S
Q
A
S
T
E
A
S
S
D
K
Site 14
T86
V
T
M
S
Q
A
S
T
E
A
S
S
D
K
V
Site 15
S89
S
Q
A
S
T
E
A
S
S
D
K
V
T
V
N
Site 16
S90
Q
A
S
T
E
A
S
S
D
K
V
T
V
N
Y
Site 17
T94
E
A
S
S
D
K
V
T
V
N
Y
Y
D
E
E
Site 18
Y97
S
D
K
V
T
V
N
Y
Y
D
E
E
G
S
I
Site 19
Y98
D
K
V
T
V
N
Y
Y
D
E
E
G
S
I
P
Site 20
S139
K
N
N
P
K
K
A
S
W
T
W
G
P
E
G
Site 21
T141
N
P
K
K
A
S
W
T
W
G
P
E
G
Q
G
Site 22
T159
L
V
N
C
D
R
E
T
P
W
L
P
K
E
D
Site 23
Y173
D
C
R
D
E
K
V
Y
S
K
E
D
L
K
D
Site 24
S174
C
R
D
E
K
V
Y
S
K
E
D
L
K
D
M
Site 25
S182
K
E
D
L
K
D
M
S
Q
M
I
L
R
T
K
Site 26
Y226
N
P
F
F
G
Q
R
Y
I
H
I
L
G
R
R
Site 27
Y236
I
L
G
R
R
K
L
Y
H
V
V
K
Y
T
G
Site 28
Y241
K
L
Y
H
V
V
K
Y
T
G
G
S
A
E
L
Site 29
Y341
E
L
K
V
C
F
Q
Y
L
N
R
G
D
R
W
Site 30
S371
G
F
P
V
V
L
D
S
P
R
D
G
N
L
K
Site 31
S401
T
R
E
P
L
F
E
S
V
T
S
L
D
S
F
Site 32
T403
E
P
L
F
E
S
V
T
S
L
D
S
F
G
N
Site 33
S407
E
S
V
T
S
L
D
S
F
G
N
L
E
V
S
Site 34
T418
L
E
V
S
P
P
V
T
V
N
G
K
T
Y
P
Site 35
S438
I
G
S
S
F
P
L
S
G
G
R
R
M
T
K
Site 36
T444
L
S
G
G
R
R
M
T
K
V
V
R
D
F
L
Site 37
S464
Q
A
P
V
E
L
Y
S
D
W
L
T
V
G
H
Site 38
T468
E
L
Y
S
D
W
L
T
V
G
H
V
D
E
F
Site 39
S522
F
K
G
L
G
G
M
S
S
K
R
I
T
I
N
Site 40
S523
K
G
L
G
G
M
S
S
K
R
I
T
I
N
K
Site 41
T527
G
M
S
S
K
R
I
T
I
N
K
I
L
S
N
Site 42
S533
I
T
I
N
K
I
L
S
N
E
S
L
V
Q
E
Site 43
S536
N
K
I
L
S
N
E
S
L
V
Q
E
N
L
Y
Site 44
Y543
S
L
V
Q
E
N
L
Y
F
Q
R
C
L
D
W
Site 45
T562
L
K
K
E
L
G
L
T
E
Q
D
I
I
D
L
Site 46
T649
L
G
E
V
H
C
G
T
N
V
R
R
K
P
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation