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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZBTB1
Full Name:
Zinc finger and BTB domain-containing protein 1
Alias:
KIAA0997; L2; Zinc finger and BTB domain containing 1
Type:
Unknown function
Mass (Da):
82016
Number AA:
713
UniProt ID:
Q9Y2K1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
K
P
S
H
S
S
Y
V
L
Q
Q
L
Site 2
Y9
A
K
P
S
H
S
S
Y
V
L
Q
Q
L
N
N
Site 3
S66
S
T
A
Q
L
N
L
S
N
M
K
I
S
A
E
Site 4
T89
M
Y
L
G
K
I
M
T
A
P
S
S
F
E
Q
Site 5
S93
K
I
M
T
A
P
S
S
F
E
Q
F
K
V
A
Site 6
Y107
A
M
N
Y
L
Q
L
Y
N
V
P
D
C
L
E
Site 7
S122
D
I
Q
D
A
D
C
S
S
S
K
C
S
S
S
Site 8
S123
I
Q
D
A
D
C
S
S
S
K
C
S
S
S
A
Site 9
S124
Q
D
A
D
C
S
S
S
K
C
S
S
S
A
S
Site 10
S127
D
C
S
S
S
K
C
S
S
S
A
S
S
K
Q
Site 11
S128
C
S
S
S
K
C
S
S
S
A
S
S
K
Q
N
Site 12
S129
S
S
S
K
C
S
S
S
A
S
S
K
Q
N
S
Site 13
S131
S
K
C
S
S
S
A
S
S
K
Q
N
S
K
M
Site 14
S132
K
C
S
S
S
A
S
S
K
Q
N
S
K
M
I
Site 15
S136
S
A
S
S
K
Q
N
S
K
M
I
F
G
V
R
Site 16
Y145
M
I
F
G
V
R
M
Y
E
D
T
V
A
R
N
Site 17
T148
G
V
R
M
Y
E
D
T
V
A
R
N
G
N
E
Site 18
T166
W
C
A
E
P
S
S
T
V
N
T
P
H
N
R
Site 19
T169
E
P
S
S
T
V
N
T
P
H
N
R
E
A
D
Site 20
S179
N
R
E
A
D
E
E
S
L
Q
L
G
N
F
P
Site 21
S196
L
F
D
V
C
K
K
S
S
V
S
K
L
S
T
Site 22
S197
F
D
V
C
K
K
S
S
V
S
K
L
S
T
P
Site 23
S202
K
S
S
V
S
K
L
S
T
P
K
E
R
V
S
Site 24
T203
S
S
V
S
K
L
S
T
P
K
E
R
V
S
R
Site 25
S209
S
T
P
K
E
R
V
S
R
R
F
G
R
S
F
Site 26
S215
V
S
R
R
F
G
R
S
F
T
C
D
S
C
G
Site 27
T217
R
R
F
G
R
S
F
T
C
D
S
C
G
F
G
Site 28
S226
D
S
C
G
F
G
F
S
C
E
K
L
L
D
E
Site 29
T237
L
L
D
E
H
V
L
T
C
T
N
R
H
L
Y
Site 30
T239
D
E
H
V
L
T
C
T
N
R
H
L
Y
Q
N
Site 31
Y244
T
C
T
N
R
H
L
Y
Q
N
T
R
S
Y
H
Site 32
Y250
L
Y
Q
N
T
R
S
Y
H
R
I
V
D
I
R
Site 33
S262
D
I
R
D
G
K
D
S
N
I
K
A
E
F
G
Site 34
S273
A
E
F
G
E
K
D
S
S
K
T
F
S
A
Q
Site 35
S274
E
F
G
E
K
D
S
S
K
T
F
S
A
Q
T
Site 36
T276
G
E
K
D
S
S
K
T
F
S
A
Q
T
D
K
Site 37
S278
K
D
S
S
K
T
F
S
A
Q
T
D
K
Y
R
Site 38
Y284
F
S
A
Q
T
D
K
Y
R
G
D
T
S
Q
A
Site 39
T288
T
D
K
Y
R
G
D
T
S
Q
A
A
D
D
S
Site 40
S289
D
K
Y
R
G
D
T
S
Q
A
A
D
D
S
A
Site 41
S295
T
S
Q
A
A
D
D
S
A
S
T
T
G
S
R
Site 42
S297
Q
A
A
D
D
S
A
S
T
T
G
S
R
K
S
Site 43
T299
A
D
D
S
A
S
T
T
G
S
R
K
S
S
T
Site 44
S301
D
S
A
S
T
T
G
S
R
K
S
S
T
V
E
Site 45
S304
S
T
T
G
S
R
K
S
S
T
V
E
S
E
I
Site 46
S305
T
T
G
S
R
K
S
S
T
V
E
S
E
I
A
Site 47
T306
T
G
S
R
K
S
S
T
V
E
S
E
I
A
S
Site 48
S309
R
K
S
S
T
V
E
S
E
I
A
S
E
E
K
Site 49
S313
T
V
E
S
E
I
A
S
E
E
K
S
R
A
A
Site 50
S317
E
I
A
S
E
E
K
S
R
A
A
E
R
K
R
Site 51
T336
M
E
P
E
D
I
P
T
D
E
L
K
D
F
N
Site 52
T348
D
F
N
I
I
K
V
T
D
K
D
C
N
E
S
Site 53
S355
T
D
K
D
C
N
E
S
T
D
N
D
E
L
E
Site 54
T356
D
K
D
C
N
E
S
T
D
N
D
E
L
E
D
Site 55
Y370
D
E
P
E
E
P
F
Y
R
Y
Y
V
E
E
D
Site 56
Y372
P
E
E
P
F
Y
R
Y
Y
V
E
E
D
V
S
Site 57
Y373
E
E
P
F
Y
R
Y
Y
V
E
E
D
V
S
I
Site 58
S379
Y
Y
V
E
E
D
V
S
I
K
K
S
G
R
K
Site 59
S383
E
D
V
S
I
K
K
S
G
R
K
T
L
K
P
Site 60
T387
I
K
K
S
G
R
K
T
L
K
P
R
M
S
V
Site 61
S393
K
T
L
K
P
R
M
S
V
S
A
D
E
R
G
Site 62
S395
L
K
P
R
M
S
V
S
A
D
E
R
G
G
L
Site 63
S411
N
M
R
P
P
N
N
S
S
P
V
Q
E
D
A
Site 64
S412
M
R
P
P
N
N
S
S
P
V
Q
E
D
A
E
Site 65
T431
E
L
C
G
L
T
I
T
E
E
D
L
S
S
H
Site 66
S436
T
I
T
E
E
D
L
S
S
H
Y
L
A
K
H
Site 67
S437
I
T
E
E
D
L
S
S
H
Y
L
A
K
H
I
Site 68
Y439
E
E
D
L
S
S
H
Y
L
A
K
H
I
E
N
Site 69
T477
C
G
E
P
Q
D
L
T
M
N
G
L
G
N
T
Site 70
S498
E
E
N
P
D
E
Q
S
E
I
R
D
M
F
V
Site 71
Y516
D
D
F
R
D
N
H
Y
Q
I
N
S
I
Q
K
Site 72
T545
N
C
G
Q
R
F
E
T
E
N
L
V
V
E
H
Site 73
S564
L
D
Q
D
M
F
K
S
A
I
M
E
E
N
E
Site 74
Y588
N
L
C
G
K
G
F
Y
Q
R
C
H
L
R
E
Site 75
Y597
R
C
H
L
R
E
H
Y
T
V
H
T
K
E
K
Site 76
T601
R
E
H
Y
T
V
H
T
K
E
K
Q
F
V
C
Site 77
Y634
M
H
K
G
M
A
R
Y
V
C
S
I
C
D
Q
Site 78
S703
N
L
R
K
D
M
R
S
H
Y
N
A
K
H
L
Site 79
Y705
R
K
D
M
R
S
H
Y
N
A
K
H
L
K
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation