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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRCH1
Full Name:
Protein TRS85 homologue
Alias:
Calponin homology domain-containing 1; CHDC1; Leucine-rich repeat and calponin homology domain-containing 1; Neuronal protein 81; NP81
Type:
Golgi apparatus protein
Mass (Da):
80885
Number AA:
728
UniProt ID:
Q9Y2L9
International Prot ID:
IPI00783220
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
A
T
P
G
S
E
P
Q
P
F
V
P
Site 2
T39
H
H
Q
H
H
G
G
T
G
A
P
G
G
A
G
Site 3
S79
N
S
G
G
L
N
L
S
A
R
K
L
K
E
F
Site 4
T89
K
L
K
E
F
P
R
T
A
A
P
G
H
D
L
Site 5
S97
A
A
P
G
H
D
L
S
D
T
V
Q
A
D
L
Site 6
T99
P
G
H
D
L
S
D
T
V
Q
A
D
L
S
K
Site 7
S105
D
T
V
Q
A
D
L
S
K
N
R
L
V
E
V
Site 8
Y128
S
L
E
I
L
N
L
Y
H
N
C
I
R
V
I
Site 9
Y147
V
N
L
Q
M
L
T
Y
L
N
L
S
R
N
Q
Site 10
S156
N
L
S
R
N
Q
L
S
A
L
P
A
C
L
C
Site 11
S179
A
S
N
N
K
L
G
S
L
P
E
E
I
G
Q
Site 12
S212
Q
Q
I
G
Q
L
K
S
L
R
E
L
N
V
R
Site 13
Y222
E
L
N
V
R
R
N
Y
L
K
V
L
P
Q
E
Site 14
S270
L
E
N
N
P
L
Q
S
P
P
A
Q
I
C
T
Site 15
Y301
I
K
T
A
D
S
L
Y
L
H
T
M
E
R
P
Site 16
S321
V
E
D
G
K
K
D
S
D
S
G
V
G
S
D
Site 17
S323
D
G
K
K
D
S
D
S
G
V
G
S
D
N
G
Site 18
S327
D
S
D
S
G
V
G
S
D
N
G
D
K
R
L
Site 19
S335
D
N
G
D
K
R
L
S
A
T
E
P
S
D
E
Site 20
S340
R
L
S
A
T
E
P
S
D
E
D
T
V
S
L
Site 21
T344
T
E
P
S
D
E
D
T
V
S
L
N
V
P
M
Site 22
S346
P
S
D
E
D
T
V
S
L
N
V
P
M
S
N
Site 23
S352
V
S
L
N
V
P
M
S
N
I
M
E
E
E
Q
Site 24
S365
E
Q
I
I
K
E
D
S
C
H
R
L
S
P
V
Site 25
S370
E
D
S
C
H
R
L
S
P
V
K
G
E
F
H
Site 26
S390
E
P
S
L
L
G
D
S
T
N
S
G
E
E
R
Site 27
T391
P
S
L
L
G
D
S
T
N
S
G
E
E
R
D
Site 28
T401
G
E
E
R
D
Q
F
T
D
R
A
D
G
L
H
Site 29
Y414
L
H
S
E
F
M
N
Y
K
A
R
A
E
D
C
Site 30
S469
L
Q
D
P
N
G
L
S
T
D
I
T
E
R
S
Site 31
T473
N
G
L
S
T
D
I
T
E
R
S
V
L
N
L
Site 32
S476
S
T
D
I
T
E
R
S
V
L
N
L
Y
P
M
Site 33
Y481
E
R
S
V
L
N
L
Y
P
M
G
S
A
E
A
Site 34
S494
E
A
L
E
L
Q
D
S
A
L
N
G
Q
I
Q
Site 35
S505
G
Q
I
Q
L
E
T
S
P
V
C
E
V
Q
S
Site 36
T515
C
E
V
Q
S
D
L
T
L
Q
S
N
G
S
Q
Site 37
S518
Q
S
D
L
T
L
Q
S
N
G
S
Q
Y
S
P
Site 38
S521
L
T
L
Q
S
N
G
S
Q
Y
S
P
N
E
I
Site 39
S524
Q
S
N
G
S
Q
Y
S
P
N
E
I
R
E
N
Site 40
S532
P
N
E
I
R
E
N
S
P
A
V
S
P
T
T
Site 41
S536
R
E
N
S
P
A
V
S
P
T
T
N
S
T
A
Site 42
T538
N
S
P
A
V
S
P
T
T
N
S
T
A
P
F
Site 43
T539
S
P
A
V
S
P
T
T
N
S
T
A
P
F
G
Site 44
S541
A
V
S
P
T
T
N
S
T
A
P
F
G
L
K
Site 45
S551
P
F
G
L
K
P
R
S
V
F
L
R
P
Q
R
Site 46
S562
R
P
Q
R
N
L
E
S
I
D
P
Q
F
T
I
Site 47
T568
N
S
P
A
V
S
P
T
T
N
S
T
A
P
F
Site 48
S589
L
V
E
Q
L
R
E
S
I
E
M
R
L
K
V
Site 49
S623
V
N
H
I
R
P
R
S
V
A
S
I
H
V
P
Site 50
S638
S
P
A
V
P
K
L
S
M
A
K
C
R
R
N
Site 51
T680
D
F
R
H
I
R
K
T
V
D
T
L
L
A
L
Site 52
T683
H
I
R
K
T
V
D
T
L
L
A
L
G
E
K
Site 53
S696
E
K
A
P
P
P
T
S
A
L
R
S
R
D
L
Site 54
S700
P
P
T
S
A
L
R
S
R
D
L
I
G
F
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation