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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MTMR15
Full Name:
Alias:
FANCD2/FANCI-associated nuclease 1;Myotubularin-related protein 15
Type:
Mass (Da):
114225
Number AA:
1017
UniProt ID:
Q9Y2M0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
D
K
K
R
P
R
R
S
L
S
I
S
K
N
K
Site 2
S18
K
R
P
R
R
S
L
S
I
S
K
N
K
K
K
Site 3
S20
P
R
R
S
L
S
I
S
K
N
K
K
K
A
S
Site 4
S27
S
K
N
K
K
K
A
S
N
S
I
I
S
C
F
Site 5
Y54
C
S
K
M
V
P
R
Y
D
L
N
R
H
L
D
Site 6
T98
S
V
T
L
E
D
V
T
P
K
K
S
P
P
P
Site 7
S102
E
D
V
T
P
K
K
S
P
P
P
K
T
N
L
Site 8
T107
K
K
S
P
P
P
K
T
N
L
T
P
G
Q
S
Site 9
T110
P
P
P
K
T
N
L
T
P
G
Q
S
D
S
A
Site 10
S114
T
N
L
T
P
G
Q
S
D
S
A
K
R
E
V
Site 11
S116
L
T
P
G
Q
S
D
S
A
K
R
E
V
K
Q
Site 12
S126
R
E
V
K
Q
K
I
S
P
Y
F
K
S
N
D
Site 13
S146
Q
D
E
L
R
N
R
S
V
K
V
I
C
L
G
Site 14
S154
V
K
V
I
C
L
G
S
L
A
S
K
L
S
R
Site 15
S160
G
S
L
A
S
K
L
S
R
K
Y
V
K
A
K
Site 16
Y163
A
S
K
L
S
R
K
Y
V
K
A
K
K
S
I
Site 17
S169
K
Y
V
K
A
K
K
S
I
D
K
D
E
E
F
Site 18
S179
K
D
E
E
F
A
G
S
S
P
Q
S
S
K
S
Site 19
S180
D
E
E
F
A
G
S
S
P
Q
S
S
K
S
T
Site 20
S183
F
A
G
S
S
P
Q
S
S
K
S
T
V
V
K
Site 21
S184
A
G
S
S
P
Q
S
S
K
S
T
V
V
K
S
Site 22
S186
S
S
P
Q
S
S
K
S
T
V
V
K
S
L
I
Site 23
T187
S
P
Q
S
S
K
S
T
V
V
K
S
L
I
D
Site 24
S191
S
K
S
T
V
V
K
S
L
I
D
N
S
S
E
Site 25
S196
V
K
S
L
I
D
N
S
S
E
I
E
D
E
D
Site 26
S197
K
S
L
I
D
N
S
S
E
I
E
D
E
D
Q
Site 27
S220
E
N
V
F
K
C
D
S
L
K
E
E
C
I
P
Site 28
S234
P
E
H
M
V
R
G
S
K
I
M
E
A
E
S
Site 29
S241
S
K
I
M
E
A
E
S
Q
K
A
T
R
E
C
Site 30
S251
A
T
R
E
C
E
K
S
A
L
T
P
G
F
S
Site 31
T254
E
C
E
K
S
A
L
T
P
G
F
S
D
N
A
Site 32
S266
D
N
A
I
M
L
F
S
P
D
F
T
L
R
N
Site 33
T270
M
L
F
S
P
D
F
T
L
R
N
T
L
K
S
Site 34
T274
P
D
F
T
L
R
N
T
L
K
S
T
S
E
D
Site 35
S277
T
L
R
N
T
L
K
S
T
S
E
D
S
L
V
Site 36
T278
L
R
N
T
L
K
S
T
S
E
D
S
L
V
K
Site 37
S279
R
N
T
L
K
S
T
S
E
D
S
L
V
K
Q
Site 38
S282
L
K
S
T
S
E
D
S
L
V
K
Q
E
C
I
Site 39
T307
H
C
E
E
V
K
M
T
V
A
S
E
A
K
I
Site 40
S317
S
E
A
K
I
Q
L
S
D
S
E
A
K
S
H
Site 41
S319
A
K
I
Q
L
S
D
S
E
A
K
S
H
S
S
Site 42
S323
L
S
D
S
E
A
K
S
H
S
S
A
D
D
A
Site 43
S326
S
E
A
K
S
H
S
S
A
D
D
A
S
A
W
Site 44
S331
H
S
S
A
D
D
A
S
A
W
S
N
I
Q
E
Site 45
S354
L
N
N
D
I
P
H
S
I
P
L
E
Q
G
S
Site 46
S361
S
I
P
L
E
Q
G
S
S
C
N
G
P
G
Q
Site 47
S362
I
P
L
E
Q
G
S
S
C
N
G
P
G
Q
T
Site 48
Y374
G
Q
T
T
G
H
P
Y
Y
L
R
S
F
L
V
Site 49
Y375
Q
T
T
G
H
P
Y
Y
L
R
S
F
L
V
V
Site 50
Y408
K
G
I
V
T
K
F
Y
Q
L
S
A
T
G
Q
Site 51
S411
V
T
K
F
Y
Q
L
S
A
T
G
Q
K
L
Y
Site 52
T413
K
F
Y
Q
L
S
A
T
G
Q
K
L
Y
V
R
Site 53
Y418
S
A
T
G
Q
K
L
Y
V
R
L
F
Q
R
K
Site 54
S427
R
L
F
Q
R
K
L
S
W
I
K
M
T
K
L
Site 55
S460
A
G
F
L
Q
T
E
S
E
L
Q
E
L
S
E
Site 56
S466
E
S
E
L
Q
E
L
S
E
V
L
E
L
L
S
Site 57
T483
E
L
K
S
L
A
K
T
F
H
L
V
N
P
N
Site 58
S508
L
K
L
A
K
Q
R
S
V
C
T
W
G
K
N
Site 59
S557
L
L
F
S
L
T
D
S
M
E
D
E
D
A
A
Site 60
S586
L
G
R
M
E
F
P
S
Y
T
I
N
R
K
T
Site 61
Y587
G
R
M
E
F
P
S
Y
T
I
N
R
K
T
H
Site 62
T588
R
M
E
F
P
S
Y
T
I
N
R
K
T
H
I
Site 63
T593
S
Y
T
I
N
R
K
T
H
I
F
Q
D
R
D
Site 64
Y605
D
R
D
D
L
I
R
Y
A
A
A
T
H
M
L
Site 65
S646
N
R
L
K
N
H
P
S
L
R
C
H
E
D
L
Site 66
S692
E
A
V
R
E
L
E
S
L
L
S
Q
R
I
Y
Site 67
S695
R
E
L
E
S
L
L
S
Q
R
I
Y
C
P
D
Site 68
Y699
S
L
L
S
Q
R
I
Y
C
P
D
S
R
G
R
Site 69
S745
V
R
T
G
H
R
L
S
L
Y
Q
R
A
V
R
Site 70
Y747
T
G
H
R
L
S
L
Y
Q
R
A
V
R
L
R
Site 71
S756
R
A
V
R
L
R
E
S
P
S
C
K
K
F
K
Site 72
S758
V
R
L
R
E
S
P
S
C
K
K
F
K
H
L
Site 73
T809
G
E
A
A
D
P
T
T
V
L
C
S
V
E
E
Site 74
Y822
E
E
L
A
L
A
H
Y
R
R
S
G
F
D
Q
Site 75
S825
A
L
A
H
Y
R
R
S
G
F
D
Q
G
I
H
Site 76
S836
Q
G
I
H
G
E
G
S
T
F
S
T
L
Y
G
Site 77
S874
P
L
D
L
C
T
D
S
F
F
T
S
R
R
P
Site 78
S878
C
T
D
S
F
F
T
S
R
R
P
A
L
E
A
Site 79
S897
I
H
D
A
P
E
E
S
L
R
A
W
V
A
A
Site 80
S915
E
Q
E
G
R
V
A
S
L
V
S
W
D
R
F
Site 81
T923
L
V
S
W
D
R
F
T
S
L
Q
Q
A
Q
D
Site 82
S924
V
S
W
D
R
F
T
S
L
Q
Q
A
Q
D
L
Site 83
S966
P
D
L
V
V
W
N
S
Q
S
R
H
F
K
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation